| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artesunate_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.25682 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.150104 |
| LDHA | lactate dehydrogenase A | 0.132143 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.112095 |
| MT2A | metallothionein 2A | 0.0933908 |
| RPL3 | ribosomal protein L3 | 0.0864946 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0757345 |
| CAPRIN2 | caprin family member 2 | 0.074761 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0733489 |
| RUNX1 | runt-related transcription factor 1 | 0.0730327 |
| TXNRD1 | thioredoxin reductase 1 | 0.0712935 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0712214 |
| EZR | ezrin | 0.0711546 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0611251 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0588626 |
| ANGPTL4 | angiopoietin-like 4 | 0.0586012 |
| RPS4X | ribosomal protein S4, X-linked | 0.0575187 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0571239 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0555231 |
| ADAR | adenosine deaminase, RNA-specific | 0.0544313 |
| TPM4 | tropomyosin 4 | 0.0527582 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0518688 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0508761 |
| RPL13A | ribosomal protein L13a | 0.0488911 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0480918 |
| HLA-B | major histocompatibility complex, class I, B | 0.0472924 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0458925 |
| PLEC | plectin | 0.0458044 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0451085 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0445576 |
| SLK | STE20-like kinase | 0.0440313 |
| YBX3 | Y box binding protein 3 | 0.0440173 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0435446 |
| RPL18A | ribosomal protein L18a | 0.0425163 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0419155 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0418455 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0410462 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0409965 |
| SVIL | supervillin | 0.0403162 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0401075 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0396908 |
| APP | amyloid beta (A4) precursor protein | 0.0395024 |
| CEP250 | centrosomal protein 250kDa | 0.0391682 |
| KRT18 | keratin 18, type I | 0.0389751 |
| TMSB4X | thymosin beta 4, X-linked | 0.0388972 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0388117 |
| RPL37 | ribosomal protein L37 | 0.038747 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0384626 |
| H1-0 | H1.0 linker histone | 0.0380819 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0378252 |
| PYGL | phosphorylase, glycogen, liver | 0.0374739 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0365398 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0359942 |
| ACTN1 | actinin, alpha 1 | 0.0352078 |
| VEGFA | vascular endothelial growth factor A | 0.0351738 |
| F2R | coagulation factor II (thrombin) receptor | 0.0349744 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0348682 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0347169 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0347047 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0346314 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0342938 |
| PLAU | plasminogen activator, urokinase | 0.0337729 |
| SDC4 | syndecan 4 | 0.0335821 |
| RTTN | rotatin | 0.0333635 |
| ERBIN | erbb2 interacting protein | 0.0333465 |
| MT1X | metallothionein 1X | 0.0327995 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0324087 |
| TPM3 | tropomyosin 3 | 0.032142 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0319351 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0317324 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311469 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0299506 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0296715 |
| PGK1 | phosphoglycerate kinase 1 | 0.029243 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0289622 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0285908 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.028239 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0279326 |
| USP11 | ubiquitin specific peptidase 11 | 0.0277848 |
| MT1E | metallothionein 1E | 0.0276631 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0274541 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0274215 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0274045 |
| MSN | moesin | 0.0273658 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.027232 |
| SPAG9 | sperm associated antigen 9 | 0.0272 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0271336 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0270872 |
| IER2 | immediate early response 2 | 0.0270728 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0270494 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0269536 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0261627 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0260817 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0260152 |
| AREG | amphiregulin | 0.0258142 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0257769 |
| FLNB | filamin B, beta | 0.0257469 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0255273 |
| HLA-A | major histocompatibility complex, class I, A | 0.0254838 |
| RPL11 | ribosomal protein L11 | 0.0254332 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.144575 |
| TMSB10 | thymosin beta 10 | -0.134559 |
| VIM | vimentin | -0.119316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113044 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112915 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.111626 |
| EHBP1 | EH domain binding protein 1 | -0.104743 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.100361 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0940887 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0840124 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0823405 |
| CD44 | CD44 molecule (Indian blood group) | -0.0726275 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0705322 |
| TP63 | tumor protein p63 | -0.0693595 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0630935 |
| EFNA5 | ephrin-A5 | -0.061791 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0616937 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0574425 |
| CADM2 | cell adhesion molecule 2 | -0.0560905 |
| EGFR | epidermal growth factor receptor | -0.0521301 |
| TNS3 | tensin 3 | -0.0520869 |
| MYOF | myoferlin | -0.0506395 |
| INTS6 | integrator complex subunit 6 | -0.0449429 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0442211 |
| RPS27A | ribosomal protein S27a | -0.0432448 |
| EPHA4 | EPH receptor A4 | -0.0424769 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0399412 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0394899 |
| AHNAK | AHNAK nucleoprotein | -0.0387925 |
| AEBP2 | AE binding protein 2 | -0.0385466 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0368076 |
| HDAC9 | histone deacetylase 9 | -0.0367988 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0367357 |
| MAP4 | microtubule-associated protein 4 | -0.0351921 |
| LRRC49 | leucine rich repeat containing 49 | -0.0341442 |
| PTMA | prothymosin, alpha | -0.0339377 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.033827 |
| NEK10 | NIMA-related kinase 10 | -0.0337464 |
| RPS24 | ribosomal protein S24 | -0.0337224 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0335104 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0331277 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0324243 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0318374 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0313726 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0313493 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0309228 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0308466 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0308105 |
| PLSCR1 | phospholipid scramblase 1 | -0.0305835 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0305759 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0300164 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0297098 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0295603 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0294002 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0291613 |
| FNIP1 | folliculin interacting protein 1 | -0.028369 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0283489 |
| USP34 | ubiquitin specific peptidase 34 | -0.0283042 |
| UBC | ubiquitin C | -0.0282181 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0281096 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0279854 |
| SP100 | SP100 nuclear antigen | -0.0279639 |
| TMEM123 | transmembrane protein 123 | -0.0279271 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0279086 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0275685 |
| DYM | dymeclin | -0.0272288 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0267928 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0266961 |
| WASF2 | WAS protein family, member 2 | -0.0266912 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266655 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0261932 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0253014 |
| ANXA1 | annexin A1 | -0.0252376 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0252375 |
| DENND1A | DENN/MADD domain containing 1A | -0.0249614 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0241757 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0239388 |
| SNX14 | sorting nexin 14 | -0.0236352 |
| RACK1 | receptor for activated C kinase 1 | -0.0236028 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0234395 |
| NAV2 | neuron navigator 2 | -0.0233884 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0229014 |
| RPL7A | ribosomal protein L7a | -0.0227249 |
| RPL36A | ribosomal protein L36a | -0.0227198 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0226995 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0226576 |
| HMGA1 | high mobility group AT-hook 1 | -0.0225446 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0223402 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0220956 |
| UBAP2 | ubiquitin associated protein 2 | -0.0218594 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0218303 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0216205 |
| HOMER1 | homer scaffolding protein 1 | -0.0215406 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0215375 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0214398 |
| FBXO11 | F-box protein 11 | -0.0211153 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0210957 |
| RPL31 | ribosomal protein L31 | -0.0209743 |
| ACTG1 | actin gamma 1 | -0.0208357 |
| RPS6 | ribosomal protein S6 | -0.0207418 |
