| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.160014 |
| SMAD3 | SMAD family member 3 | 0.128227 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0991781 |
| VEGFA | vascular endothelial growth factor A | 0.0921042 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0915662 |
| NAV2 | neuron navigator 2 | 0.0892731 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0812236 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0752209 |
| LDHA | lactate dehydrogenase A | 0.0722561 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0704862 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0679918 |
| TGM2 | transglutaminase 2 | 0.0670961 |
| FAM20C | family with sequence similarity 20, member C | 0.066032 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0605532 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0594287 |
| MCL1 | myeloid cell leukemia 1 | 0.0585432 |
| RPL3 | ribosomal protein L3 | 0.0559169 |
| LOXL2 | lysyl oxidase-like 2 | 0.0553888 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0538961 |
| PCBP2 | poly(rC) binding protein 2 | 0.0522956 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0494137 |
| FLNB | filamin B, beta | 0.0471869 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0443507 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0429867 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0426938 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0423098 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0421207 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0404613 |
| SEPTIN9 | septin 9 | 0.0389975 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0387958 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0385235 |
| NDRG1 | N-myc downstream regulated 1 | 0.0384503 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0378151 |
| FAM107B | family with sequence similarity 107, member B | 0.0377829 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0375363 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0356504 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0349415 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0344482 |
| BRD2 | bromodomain containing 2 | 0.0339633 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0321759 |
| FLNA | filamin A, alpha | 0.032031 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0317933 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.031445 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0313119 |
| ADD3 | adducin 3 (gamma) | 0.0312833 |
| MYO10 | myosin X | 0.0311373 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.030695 |
| PLEC | plectin | 0.0305335 |
| ECE1 | endothelin converting enzyme 1 | 0.0305116 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0303497 |
| CEP250 | centrosomal protein 250kDa | 0.0303461 |
| MSN | moesin | 0.0299526 |
| CPNE1 | copine I | 0.0298391 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0293858 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0290514 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0285104 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0276948 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0269474 |
| TUT7 | terminal uridylyl transferase 7 | 0.0269258 |
| SIK3 | SIK family kinase 3 | 0.026761 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0267363 |
| CD44 | CD44 molecule (Indian blood group) | 0.0267147 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0264078 |
| OPTN | optineurin | 0.0263885 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.026297 |
| COPA | coatomer protein complex, subunit alpha | 0.0260539 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0254839 |
| CANX | calnexin | 0.0252015 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0251908 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0251202 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0246748 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0246022 |
| HDLBP | high density lipoprotein binding protein | 0.0241613 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0239074 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0238016 |
| ATXN1 | ataxin 1 | 0.0237196 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0234723 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0232791 |
| ANGPTL4 | angiopoietin-like 4 | 0.0231657 |
| APP | amyloid beta (A4) precursor protein | 0.0231184 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0231147 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0230725 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0230118 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.022949 |
| RPL13A | ribosomal protein L13a | 0.0228498 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.0227869 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0226449 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0226093 |
| PFKP | phosphofructokinase, platelet | 0.0224138 |
| ADAR | adenosine deaminase, RNA-specific | 0.02188 |
| TNS1 | tensin 1 | 0.0218373 |
| NPTN | neuroplastin | 0.0216066 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0215948 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0212733 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0212247 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0209848 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0207834 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.020422 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0203743 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0199728 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.240411 |
| FN1 | fibronectin 1 | -0.159515 |
| DPYD | dihydropyrimidine dehydrogenase | -0.115447 |
| TMSB10 | thymosin beta 10 | -0.106914 |
| NRG1 | neuregulin 1 | -0.103397 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.102075 |
| CDH13 | cadherin 13 | -0.0969997 |
| HMGA2 | high mobility group AT-hook 2 | -0.0965488 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0957268 |
| GPC6 | glypican 6 | -0.0884597 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0801348 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0714429 |
| DST | dystonin | -0.0707404 |
| USP34 | ubiquitin specific peptidase 34 | -0.0685492 |
| GLCCI1 | glucocorticoid induced 1 | -0.0667596 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0612821 |
| ZNF804A | zinc finger protein 804A | -0.0600093 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0598325 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0559759 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0558151 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0549075 |
| LOX | lysyl oxidase | -0.054206 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0525175 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0525025 |
| MECOM | MDS1 and EVI1 complex locus | -0.0475691 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0467857 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0452906 |
| CDK14 | cyclin-dependent kinase 14 | -0.0443603 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0437639 |
| MEF2A | myocyte enhancer factor 2A | -0.043758 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0435908 |
| STC1 | stanniocalcin 1 | -0.043256 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0430909 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0427854 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0420707 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0420421 |
| OXR1 | oxidation resistance 1 | -0.0413665 |
| PTMA | prothymosin, alpha | -0.038274 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0381172 |
| OSMR | oncostatin M receptor | -0.0379909 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0378271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0370216 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0369232 |
| PRR16 | proline rich 16 | -0.0364113 |
| VIM | vimentin | -0.0361597 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0332722 |
| GLIS3 | GLIS family zinc finger 3 | -0.0329865 |
| DIAPH2 | diaphanous-related formin 2 | -0.0328459 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0324524 |
| CUX1 | cut-like homeobox 1 | -0.0324037 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0313976 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0312136 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0310179 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0310125 |
| VRK2 | vaccinia related kinase 2 | -0.0309988 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0307361 |
| NAV3 | neuron navigator 3 | -0.0306287 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.03061 |
| IER3 | immediate early response 3 | -0.030555 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0301867 |
| MTSS1 | metastasis suppressor 1 | -0.0295824 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0295318 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0289885 |
| ETV6 | ets variant 6 | -0.0283948 |
| JMJD1C | jumonji domain containing 1C | -0.0280789 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0279561 |
| CFAP20DC | CFAP20 domain containing | -0.0279558 |
| S100A6 | S100 calcium binding protein A6 | -0.0277768 |
| NF1 | neurofibromin 1 | -0.0276437 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0272668 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0269373 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0267663 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0266687 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0261032 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0260815 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0260472 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0259174 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0254239 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0248657 |
| ANTXR1 | anthrax toxin receptor 1 | -0.024353 |
| PRRX1 | paired related homeobox 1 | -0.0238456 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0237886 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237435 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0234462 |
| VCL | vinculin | -0.0234041 |
| ASPH | aspartate beta-hydroxylase | -0.0231701 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0230761 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0229064 |
| KYNU | kynureninase | -0.0226785 |
| CP | ceruloplasmin (ferroxidase) | -0.0225249 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0224007 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0223149 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0223056 |
| MX2 | MX dynamin-like GTPase 2 | -0.0222612 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0221987 |
| SYT1 | synaptotagmin I | -0.0221097 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0220245 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.022014 |
| BMERB1 | bMERB domain containing 1 | -0.0217579 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0217521 |
