| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.210811 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.192193 |
| GRAMD1B | GRAM domain containing 1B | 0.178346 |
| LDHA | lactate dehydrogenase A | 0.177134 |
| PM20D1 | peptidase M20 domain containing 1 | 0.167299 |
| RPL3 | ribosomal protein L3 | 0.121998 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.110687 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.106092 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0813317 |
| FAM107B | family with sequence similarity 107, member B | 0.0759848 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.074551 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0699398 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0697181 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.06969 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.067879 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0667859 |
| TPM3 | tropomyosin 3 | 0.0652445 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0647276 |
| FGB | fibrinogen beta chain | 0.0645565 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0644466 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0626844 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0610928 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0598836 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0581353 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0570546 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0569707 |
| FLNA | filamin A, alpha | 0.0566643 |
| SVIL | supervillin | 0.056454 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0557498 |
| BRD2 | bromodomain containing 2 | 0.055297 |
| ACTN1 | actinin, alpha 1 | 0.0546913 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0542077 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0541767 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0526978 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0510608 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0496689 |
| WWOX | WW domain containing oxidoreductase | 0.0490982 |
| PCBP2 | poly(rC) binding protein 2 | 0.0487193 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0480667 |
| HDGF | hepatoma-derived growth factor | 0.0477482 |
| APP | amyloid beta (A4) precursor protein | 0.0470069 |
| TXNRD1 | thioredoxin reductase 1 | 0.0456534 |
| KYNU | kynureninase | 0.0436702 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.043397 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0427079 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0411399 |
| POTEF | POTE ankyrin domain family, member F | 0.0398108 |
| RPL13A | ribosomal protein L13a | 0.0389735 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0389647 |
| MSN | moesin | 0.0388835 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.038418 |
| FNDC3B | fibronectin type III domain containing 3B | 0.037979 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0377435 |
| RPL18A | ribosomal protein L18a | 0.0373597 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0372505 |
| ATXN1 | ataxin 1 | 0.0370713 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0362955 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0362671 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0361239 |
| IL6 | interleukin 6 | 0.0355891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0347129 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0346323 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0331962 |
| PLS3 | plastin 3 | 0.0329853 |
| ADAR | adenosine deaminase, RNA-specific | 0.0315866 |
| CMIP | c-Maf inducing protein | 0.0314563 |
| ASPH | aspartate beta-hydroxylase | 0.0309068 |
| CALR | calreticulin | 0.0308708 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0307779 |
| RPS4X | ribosomal protein S4, X-linked | 0.0303245 |
| CD99 | CD99 molecule | 0.030018 |
| MYOF | myoferlin | 0.0300125 |
| HLA-A | major histocompatibility complex, class I, A | 0.029881 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0290534 |
| INHBA | inhibin, beta A | 0.0284079 |
| CANX | calnexin | 0.0282201 |
| PLEC | plectin | 0.027981 |
| RAD51B | RAD51 paralog B | 0.0278536 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0277296 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.027701 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0275074 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0274922 |
| EGR1 | early growth response 1 | 0.0270492 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0268902 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0268151 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0267131 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0266568 |
| PFKP | phosphofructokinase, platelet | 0.0261061 |
| KRT18 | keratin 18, type I | 0.0258151 |
| DOCK5 | dedicator of cytokinesis 5 | 0.025785 |
| PRDX1 | peroxiredoxin 1 | 0.0257363 |
| BMP6 | bone morphogenetic protein 6 | 0.0256779 |
| RRM2 | ribonucleotide reductase M2 | 0.0255767 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0254228 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0253056 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0246099 |
| TPI1 | triosephosphate isomerase 1 | 0.0244031 |
| AXL | AXL receptor tyrosine kinase | 0.0243171 |
| VEGFA | vascular endothelial growth factor A | 0.024167 |
| CPNE1 | copine I | 0.0238149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.120958 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102314 |
| MT2A | metallothionein 2A | -0.0929346 |
| TMSB10 | thymosin beta 10 | -0.0865761 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0834755 |
| IGF2 | insulin-like growth factor 2 | -0.0758461 |
| IER3 | immediate early response 3 | -0.0704657 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0697589 |
| PTMA | prothymosin, alpha | -0.0687213 |
| CAVIN1 | caveolae associated protein 1 | -0.0576755 |
| ACTG1 | actin gamma 1 | -0.0475942 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0473741 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0439054 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0436311 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0376964 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0376066 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0368385 |
| RPS6 | ribosomal protein S6 | -0.0350468 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0349644 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0343095 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0335295 |
| USP3 | ubiquitin specific peptidase 3 | -0.0320798 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0320791 |
| S100A10 | S100 calcium binding protein A10 | -0.0313073 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0313008 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0312426 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0308843 |
| PFDN2 | prefoldin subunit 2 | -0.0308037 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0304973 |
| NOP58 | NOP58 ribonucleoprotein | -0.0300217 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0286712 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0285252 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0281749 |
| S100A6 | S100 calcium binding protein A6 | -0.0279926 |
| RPS27A | ribosomal protein S27a | -0.0277764 |
| RPS24 | ribosomal protein S24 | -0.0276579 |
| PUM2 | pumilio RNA-binding family member 2 | -0.027129 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0270639 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0268727 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0267748 |
| RPS2 | ribosomal protein S2 | -0.0267736 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0267433 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0267309 |
| RPL36 | ribosomal protein L36 | -0.0266468 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0260348 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0257827 |
| FTL | ferritin, light polypeptide | -0.0257531 |
| ZNF292 | zinc finger protein 292 | -0.0253853 |
| RPL34 | ribosomal protein L34 | -0.0252061 |
| RHEB | Ras homolog enriched in brain | -0.0251871 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0248945 |
| RPS25 | ribosomal protein S25 | -0.0244346 |
| RACK1 | receptor for activated C kinase 1 | -0.0243193 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0242295 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0240686 |
| RPL26 | ribosomal protein L26 | -0.0240115 |
| GOLT1B | golgi transport 1B | -0.0238673 |
| WASF2 | WAS protein family, member 2 | -0.0238366 |
| TMEM123 | transmembrane protein 123 | -0.0237122 |
| HMGA1 | high mobility group AT-hook 1 | -0.0235289 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0235063 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0234945 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0233721 |
| DENND4A | DENN/MADD domain containing 4A | -0.0229829 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0229412 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0225708 |
| RPS8 | ribosomal protein S8 | -0.0225086 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0223988 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0222631 |
| RPS16 | ribosomal protein S16 | -0.022211 |
| IMMT | inner membrane protein, mitochondrial | -0.0220847 |
| WDR43 | WD repeat domain 43 | -0.022004 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0215937 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0213888 |
| PARK7 | parkinson protein 7 | -0.0213509 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0213263 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.021176 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0211295 |
| RPL38 | ribosomal protein L38 | -0.0210926 |
| ABI1 | abl-interactor 1 | -0.0209445 |
| SEPTIN7 | septin 7 | -0.0205781 |
| AK1 | adenylate kinase 1 | -0.0205549 |
| MATR3 | matrin 3 | -0.0205212 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0204242 |
| PHF20 | PHD finger protein 20 | -0.0202101 |
| SRGN | serglycin | -0.0200188 |
| RTN4 | reticulon 4 | -0.019908 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0198731 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0197244 |
| CDK6 | cyclin-dependent kinase 6 | -0.0196597 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0196311 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.019514 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0194987 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0194475 |
| RPLP1 | ribosomal protein, large, P1 | -0.019335 |
| TLK1 | tousled-like kinase 1 | -0.0193126 |
| TPD52 | tumor protein D52 | -0.0193044 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0191799 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0191055 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0190246 |
