| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artesunate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.13408 |
| LMO7 | LIM domain 7 | 0.128157 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.100327 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0906768 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0717631 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0707319 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0700577 |
| HMGA2 | high mobility group AT-hook 2 | 0.0673631 |
| FLNB | filamin B, beta | 0.0598211 |
| MCL1 | myeloid cell leukemia 1 | 0.059297 |
| VEGFA | vascular endothelial growth factor A | 0.058417 |
| COL5A1 | collagen, type V, alpha 1 | 0.0537766 |
| SEPTIN9 | septin 9 | 0.0536953 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0534464 |
| YTHDC1 | YTH domain containing 1 | 0.05243 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0511953 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.050926 |
| PCBP2 | poly(rC) binding protein 2 | 0.0506541 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0500842 |
| GLIS3 | GLIS family zinc finger 3 | 0.049886 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0496792 |
| KRT17 | keratin 17, type I | 0.0490743 |
| AHNAK | AHNAK nucleoprotein | 0.0487841 |
| PDLIM5 | PDZ and LIM domain 5 | 0.047093 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0469168 |
| SMAD3 | SMAD family member 3 | 0.046834 |
| RNF213 | ring finger protein 213 | 0.0468016 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0460628 |
| CANX | calnexin | 0.0459445 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0448829 |
| INTS6 | integrator complex subunit 6 | 0.0443786 |
| ATOSA | atos homolog A | 0.0442884 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0442784 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0441031 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0437145 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0428329 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0423649 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0422485 |
| DNMBP | dynamin binding protein | 0.041361 |
| MYO9B | myosin IXB | 0.041313 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0408438 |
| EFNB2 | ephrin-B2 | 0.0407624 |
| CLIC4 | chloride intracellular channel 4 | 0.0405197 |
| WWC2 | WW and C2 domain containing 2 | 0.0403138 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0398586 |
| PAPOLA | poly(A) polymerase alpha | 0.0394988 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0392144 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0380777 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379109 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0377102 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0376092 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0374118 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0370336 |
| IPO7 | importin 7 | 0.0370221 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0369853 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.036053 |
| TLK1 | tousled-like kinase 1 | 0.0359797 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0357532 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0356651 |
| RPL4 | ribosomal protein L4 | 0.0353307 |
| FAM168A | family with sequence similarity 168, member A | 0.0352559 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0351758 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0350705 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0347846 |
| ZNF638 | zinc finger protein 638 | 0.0344928 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0340523 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0337762 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0333294 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0331478 |
| USP53 | ubiquitin specific peptidase 53 | 0.033081 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0330792 |
| LDHA | lactate dehydrogenase A | 0.0330613 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0330228 |
| COL5A2 | collagen, type V, alpha 2 | 0.0329728 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0329174 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0328691 |
| VCL | vinculin | 0.0327937 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0327731 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0326329 |
| ADAR | adenosine deaminase, RNA-specific | 0.0326077 |
| PHF21A | PHD finger protein 21A | 0.0321661 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0321522 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0320694 |
| ATF6 | activating transcription factor 6 | 0.0319978 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.031961 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0319441 |
| COLEC11 | collectin sub-family member 11 | 0.0318936 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0317198 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0315177 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0314491 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0314226 |
| DTNA | dystrobrevin, alpha | 0.0313642 |
| USP47 | ubiquitin specific peptidase 47 | 0.0313212 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0312027 |
| HDLBP | high density lipoprotein binding protein | 0.031166 |
| FHIT | fragile histidine triad | 0.0310175 |
| FOXO1 | forkhead box O1 | 0.0306259 |
| APP | amyloid beta (A4) precursor protein | 0.0304309 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0302334 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 0.0301668 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182161 |
| FTL | ferritin, light polypeptide | -0.0973175 |
| TMSB10 | thymosin beta 10 | -0.0935677 |
| MT2A | metallothionein 2A | -0.0844744 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0825481 |
| VIM | vimentin | -0.0726653 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0721256 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0716366 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0675573 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0641792 |
| B2M | beta-2-microglobulin | -0.0634856 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0623294 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0567045 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0559809 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0557793 |
| STC1 | stanniocalcin 1 | -0.0554944 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0541496 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0517809 |
| MUC16 | mucin 16, cell surface associated | -0.0501933 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0499829 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0498789 |
| SPAG9 | sperm associated antigen 9 | -0.0489638 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0480654 |
| FN1 | fibronectin 1 | -0.0475884 |
| RIGI | RNA sensor RIG-I | -0.0468669 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0468375 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0466894 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0464815 |
| SRPK2 | SRSF protein kinase 2 | -0.0460916 |
| SETD5 | SET domain containing 5 | -0.0455341 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0450996 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0447797 |
| PERP | PERP, TP53 apoptosis effector | -0.0445309 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0440503 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0417323 |
| TAOK3 | TAO kinase 3 | -0.041379 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0411989 |
| NBEAL1 | neurobeachin-like 1 | -0.0410323 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0407244 |
| MYO1E | myosin IE | -0.0407223 |
| ABLIM1 | actin binding LIM protein 1 | -0.0403248 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0397479 |
| RPL35A | ribosomal protein L35a | -0.0395318 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0388962 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0388193 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0371959 |
| PTMA | prothymosin, alpha | -0.0370903 |
| MSI2 | musashi RNA-binding protein 2 | -0.0370022 |
| CUX1 | cut-like homeobox 1 | -0.0369343 |
| RAD51B | RAD51 paralog B | -0.0362777 |
| MYO9A | myosin IXA | -0.0362668 |
| NEK7 | NIMA-related kinase 7 | -0.0359866 |
| ASPH | aspartate beta-hydroxylase | -0.035958 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0359039 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0358689 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0358545 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0357842 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0353114 |
| LAMB3 | laminin, beta 3 | -0.0352511 |
| CCNI | cyclin I | -0.0351661 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0345951 |
| OSMR | oncostatin M receptor | -0.0344866 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0344608 |
| MED13L | mediator complex subunit 13-like | -0.0344521 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.033939 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.033281 |
| ENO1 | enolase 1, (alpha) | -0.0332732 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0331785 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330913 |
| UBC | ubiquitin C | -0.0330006 |
| ACTG1 | actin gamma 1 | -0.0326627 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0325782 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0324977 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0324198 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.032302 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0321237 |
| PARD3 | par-3 family cell polarity regulator | -0.0319778 |
| SDC4 | syndecan 4 | -0.0316187 |
| OGA | O-GlcNAcase | -0.031546 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0315371 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0314672 |
| RPLP1 | ribosomal protein, large, P1 | -0.0313495 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0312429 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0311878 |
| GOLGA4 | golgin A4 | -0.0310181 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0309785 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0309625 |
| JUP | junction plakoglobin | -0.0309269 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0308606 |
| RPL31 | ribosomal protein L31 | -0.0307892 |
| SVIL | supervillin | -0.0302643 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.030205 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0293965 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.02933 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0292453 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0289648 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0287066 |
| UBE3A | ubiquitin protein ligase E3A | -0.0286688 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0285237 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0284506 |
