| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.276605 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.18548 |
| MCL1 | myeloid cell leukemia 1 | 0.125449 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.125302 |
| KRT18 | keratin 18, type I | 0.0854788 |
| RPL3 | ribosomal protein L3 | 0.0822196 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0787196 |
| YBX3 | Y box binding protein 3 | 0.07755 |
| TXNRD1 | thioredoxin reductase 1 | 0.0707056 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0681525 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0664819 |
| TPM3 | tropomyosin 3 | 0.058836 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0587044 |
| ADAR | adenosine deaminase, RNA-specific | 0.0565967 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0561866 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0554445 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0537396 |
| GRAMD1B | GRAM domain containing 1B | 0.0506249 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0504272 |
| LDHA | lactate dehydrogenase A | 0.0499676 |
| RPS4X | ribosomal protein S4, X-linked | 0.0443698 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0436825 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0425323 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0411769 |
| FLNA | filamin A, alpha | 0.040911 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0402411 |
| ACTN1 | actinin, alpha 1 | 0.0402331 |
| TPM2 | tropomyosin 2 (beta) | 0.037294 |
| SET | SET nuclear proto-oncogene | 0.036994 |
| CTTN | cortactin | 0.0366284 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0363687 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0363192 |
| PLEC | plectin | 0.0352074 |
| MKI67 | marker of proliferation Ki-67 | 0.0349958 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.034279 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0341348 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0336902 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0333534 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0331533 |
| OGA | O-GlcNAcase | 0.0329953 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0327919 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0327641 |
| TPM4 | tropomyosin 4 | 0.0323515 |
| MAGEA4 | melanoma antigen family A4 | 0.0318445 |
| CEP250 | centrosomal protein 250kDa | 0.0317183 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0315362 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0307327 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0304327 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0302215 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0289817 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.028368 |
| BRD2 | bromodomain containing 2 | 0.0280721 |
| APP | amyloid beta (A4) precursor protein | 0.0277925 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0275902 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0274484 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0271567 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0270198 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0268989 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0262558 |
| RRM2 | ribonucleotide reductase M2 | 0.0253242 |
| CPNE1 | copine I | 0.025301 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0249882 |
| DENR | density-regulated protein | 0.024957 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0248142 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0247742 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0244437 |
| CAPRIN2 | caprin family member 2 | 0.0244331 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0242204 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0240961 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0239238 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0236653 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0236442 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0236014 |
| CANX | calnexin | 0.0233872 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233522 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.022581 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0222799 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0222509 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0221867 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0221163 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0219712 |
| IPO7 | importin 7 | 0.0218498 |
| HOMER1 | homer scaffolding protein 1 | 0.0209128 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0208518 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0208499 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0207245 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0206994 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0205053 |
| TPI1 | triosephosphate isomerase 1 | 0.0204654 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0203863 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0202681 |
| TLN1 | talin 1 | 0.0202083 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0198259 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0196963 |
| ZYX | zyxin | 0.0196205 |
| ACTG1 | actin gamma 1 | 0.0195781 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0192898 |
| RPL13A | ribosomal protein L13a | 0.0191849 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0191641 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0187557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128857 |
| RAD51B | RAD51 paralog B | -0.113988 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0800912 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0701511 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0694012 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0601271 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0556839 |
| TMSB10 | thymosin beta 10 | -0.0518666 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0503696 |
| ATXN1 | ataxin 1 | -0.0502579 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0453088 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0444933 |
| AFF3 | AF4/FMR2 family, member 3 | -0.043362 |
| HMGA2 | high mobility group AT-hook 2 | -0.0429445 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0418299 |
| EGFR | epidermal growth factor receptor | -0.041638 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0386817 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0379202 |
| USP34 | ubiquitin specific peptidase 34 | -0.0372273 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0372018 |
| NF1 | neurofibromin 1 | -0.0367127 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.035097 |
| EGR1 | early growth response 1 | -0.034417 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.034123 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0341149 |
| PTK2 | protein tyrosine kinase 2 | -0.0336712 |
| CUX1 | cut-like homeobox 1 | -0.0335644 |
| TMEM165 | transmembrane protein 165 | -0.032542 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0321918 |
| PFN1 | profilin 1 | -0.0317004 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0315048 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0310953 |
| RYR3 | ryanodine receptor 3 | -0.0289358 |
| WASF2 | WAS protein family, member 2 | -0.0287663 |
| VIM | vimentin | -0.0283361 |
| AEBP2 | AE binding protein 2 | -0.0280567 |
| RPL35A | ribosomal protein L35a | -0.0279224 |
| RSF1 | remodeling and spacing factor 1 | -0.0276397 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.027515 |
| EXOC4 | exocyst complex component 4 | -0.0272509 |
| WDR70 | WD repeat domain 70 | -0.0270675 |
| PDE10A | phosphodiesterase 10A | -0.0270405 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0268085 |
| SBF2 | SET binding factor 2 | -0.0268077 |
| RPS27 | ribosomal protein S27 | -0.0261273 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0261183 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0257888 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0257297 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0256876 |
| GPHN | gephyrin | -0.0251525 |
| RPS8 | ribosomal protein S8 | -0.0251206 |
| RPL37A | ribosomal protein L37a | -0.0250565 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0250102 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0247957 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0245507 |
| RPS29 | ribosomal protein S29 | -0.0244547 |
| DIAPH2 | diaphanous-related formin 2 | -0.0243944 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0238992 |
| FMN1 | formin 1 | -0.023373 |
| PTMA | prothymosin, alpha | -0.02314 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0229244 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0228568 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0224728 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0223749 |
| HDAC8 | histone deacetylase 8 | -0.02221 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0220234 |
| RPLP2 | ribosomal protein, large, P2 | -0.0219948 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.021968 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0217359 |
| RPS21 | ribosomal protein S21 | -0.0215185 |
| RPLP1 | ribosomal protein, large, P1 | -0.0214399 |
| RPS15 | ribosomal protein S15 | -0.0212256 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0211202 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0209073 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.020851 |
| RPS19 | ribosomal protein S19 | -0.0206598 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0206002 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0205973 |
| MAP4 | microtubule-associated protein 4 | -0.020496 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0204502 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0203651 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.020321 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.020314 |
| POTEF | POTE ankyrin domain family, member F | -0.0199328 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0199126 |
| MFSD4B | major facilitator superfamily domain containing 4B | -0.0197494 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0195176 |
| TAPBP | TAP binding protein (tapasin) | -0.0193845 |
| KIAA1328 | KIAA1328 | -0.0192842 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0192373 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0191858 |
| RPL32 | ribosomal protein L32 | -0.0189987 |
| CCDC91 | coiled-coil domain containing 91 | -0.0189771 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0186032 |
| LATS2 | large tumor suppressor kinase 2 | -0.0185464 |
| ZNF292 | zinc finger protein 292 | -0.0184997 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0183806 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0181959 |
| EHBP1 | EH domain binding protein 1 | -0.0180849 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0180783 |
