| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artesunate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.176121 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.165012 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.154124 |
| LDHA | lactate dehydrogenase A | 0.15212 |
| PLEC | plectin | 0.149459 |
| VEGFA | vascular endothelial growth factor A | 0.137106 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.116487 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.111914 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0924215 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0915799 |
| LAMB3 | laminin, beta 3 | 0.0808776 |
| RPL3 | ribosomal protein L3 | 0.0742263 |
| AHNAK | AHNAK nucleoprotein | 0.0739744 |
| CANX | calnexin | 0.0737731 |
| ERBIN | erbb2 interacting protein | 0.0709263 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0691648 |
| DSPP | dentin sialophosphoprotein | 0.0656599 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0629242 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0615202 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0605038 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0593226 |
| FTL | ferritin, light polypeptide | 0.0581041 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0568742 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0568406 |
| FBXO32 | F-box protein 32 | 0.0558865 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0556899 |
| MCL1 | myeloid cell leukemia 1 | 0.055508 |
| MSN | moesin | 0.0552675 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0549394 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0544817 |
| MAP1B | microtubule-associated protein 1B | 0.0541403 |
| FLNB | filamin B, beta | 0.053353 |
| UBC | ubiquitin C | 0.0518379 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0517717 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0502438 |
| EFNA5 | ephrin-A5 | 0.0490473 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0484047 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0481812 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0474772 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0471855 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0468943 |
| APP | amyloid beta (A4) precursor protein | 0.0463728 |
| HLA-A | major histocompatibility complex, class I, A | 0.0462854 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0459825 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0449709 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0448888 |
| LMO7 | LIM domain 7 | 0.0448017 |
| CTSB | cathepsin B | 0.0443134 |
| FLNA | filamin A, alpha | 0.0437019 |
| KRT18 | keratin 18, type I | 0.0429636 |
| MYO6 | myosin VI | 0.0427771 |
| RNF213 | ring finger protein 213 | 0.0425385 |
| RAI14 | retinoic acid induced 14 | 0.042442 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0416341 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0413382 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0410104 |
| GOLGB1 | golgin B1 | 0.040985 |
| TPM3 | tropomyosin 3 | 0.0406575 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0402303 |
| TPM4 | tropomyosin 4 | 0.0402007 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0398706 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0393023 |
| CTBP2 | C-terminal binding protein 2 | 0.0383038 |
| MYO5B | myosin VB | 0.0377066 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0376994 |
| TXNIP | thioredoxin interacting protein | 0.0373186 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.037287 |
| MX1 | MX dynamin-like GTPase 1 | 0.0363484 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0353186 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0350744 |
| ADAR | adenosine deaminase, RNA-specific | 0.0349163 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.034848 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0346966 |
| TMF1 | TATA element modulatory factor 1 | 0.0340763 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0339258 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0336834 |
| RCOR1 | REST corepressor 1 | 0.0335056 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0334319 |
| MYO10 | myosin X | 0.0333816 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0330524 |
| RBM47 | RNA binding motif protein 47 | 0.0330229 |
| ARRDC3 | arrestin domain containing 3 | 0.0329814 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.032973 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0328725 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0325662 |
| FNBP4 | formin binding protein 4 | 0.0322042 |
| HDLBP | high density lipoprotein binding protein | 0.0320798 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0320026 |
| RPL18A | ribosomal protein L18a | 0.0318822 |
| EZR | ezrin | 0.0312332 |
| HDGF | hepatoma-derived growth factor | 0.0307237 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0306773 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.029784 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0297475 |
| MYO1E | myosin IE | 0.0296679 |
| LASP1 | LIM and SH3 protein 1 | 0.0294535 |
| PCBP2 | poly(rC) binding protein 2 | 0.0291206 |
| JUP | junction plakoglobin | 0.0290772 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0288384 |
| FNBP1L | formin binding protein 1-like | 0.0288326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.251092 |
| FN1 | fibronectin 1 | -0.124138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.111546 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0834118 |
| HMGA1 | high mobility group AT-hook 1 | -0.0777948 |
| ASPH | aspartate beta-hydroxylase | -0.0732247 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0550194 |
| TMSB10 | thymosin beta 10 | -0.0522962 |
| TFG | TRK-fused gene | -0.0517191 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0512972 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0495994 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0482205 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0475633 |
| S100A6 | S100 calcium binding protein A6 | -0.0470294 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0466768 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0464232 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0449577 |
| ZNF292 | zinc finger protein 292 | -0.0445226 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0433706 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0408978 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0405752 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0398179 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0387036 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0383368 |
| RACK1 | receptor for activated C kinase 1 | -0.0371543 |
| RPL34 | ribosomal protein L34 | -0.0370648 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0361891 |
| RPL9 | ribosomal protein L9 | -0.0354986 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0348896 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0346396 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0345125 |
| RPLP0 | ribosomal protein, large, P0 | -0.0332566 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0326963 |
| GOLGA4 | golgin A4 | -0.0325713 |
| RPL32 | ribosomal protein L32 | -0.0320556 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0314244 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0313338 |
| RYBP | RING1 and YY1 binding protein | -0.0311864 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0309301 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0307699 |
| RPS24 | ribosomal protein S24 | -0.0306733 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0303763 |
| QKI | QKI, KH domain containing, RNA binding | -0.029979 |
| RPS23 | ribosomal protein S23 | -0.0299778 |
| FAM162A | family with sequence similarity 162, member A | -0.0299201 |
| ANXA5 | annexin A5 | -0.0298762 |
| RPL30 | ribosomal protein L30 | -0.0295566 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0291599 |
| RHEB | Ras homolog enriched in brain | -0.0286965 |
| PAPOLA | poly(A) polymerase alpha | -0.0284102 |
| PEG10 | paternally expressed 10 | -0.0284028 |
| MATR3 | matrin 3 | -0.0279875 |
| TMEM263 | transmembrane protein 263 | -0.0279586 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0274986 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0272872 |
| RPS8 | ribosomal protein S8 | -0.0271681 |
| RPS2 | ribosomal protein S2 | -0.0270082 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0268642 |
| MIS18BP1 | MIS18 binding protein 1 | -0.026791 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0266473 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0265776 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0262421 |
| RPS6 | ribosomal protein S6 | -0.0261929 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.025882 |
| EREG | epiregulin | -0.0257537 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0255512 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0254202 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0249843 |
| AREG | amphiregulin | -0.0249114 |
| SEPTIN7 | septin 7 | -0.0245575 |
| CDC73 | cell division cycle 73 | -0.0244541 |
| RNF145 | ring finger protein 145 | -0.0243792 |
| IL6ST | interleukin 6 signal transducer | -0.024331 |
| FAM13A | family with sequence similarity 13, member A | -0.0239399 |
| CCNI | cyclin I | -0.0237638 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.023598 |
| TXNRD1 | thioredoxin reductase 1 | -0.0234693 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0234129 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0234024 |
| RPL12 | ribosomal protein L12 | -0.0233027 |
| CCNL1 | cyclin L1 | -0.0231644 |
| S100A10 | S100 calcium binding protein A10 | -0.0227056 |
| USP3 | ubiquitin specific peptidase 3 | -0.0226988 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0226975 |
| RLF | rearranged L-myc fusion | -0.0225772 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0224242 |
| CDK17 | cyclin-dependent kinase 17 | -0.022331 |
| TUBA1B | tubulin, alpha 1b | -0.0222172 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.022182 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0219032 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0217978 |
| RPL35A | ribosomal protein L35a | -0.0214166 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0212548 |
| TRAM1 | translocation associated membrane protein 1 | -0.0210729 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.02102 |
| HMGB2 | high mobility group box 2 | -0.0209416 |
| ATP13A3 | ATPase type 13A3 | -0.0207479 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0206797 |
| CHMP2B | charged multivesicular body protein 2B | -0.0206078 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0202752 |
