| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.174679 |
| LAMA4 | laminin, alpha 4 | 0.144913 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.139267 |
| WWOX | WW domain containing oxidoreductase | 0.119165 |
| PCBP2 | poly(rC) binding protein 2 | 0.0972233 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0957318 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0943761 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0826776 |
| EFNA5 | ephrin-A5 | 0.0824805 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0808436 |
| MYOF | myoferlin | 0.0803363 |
| DSPP | dentin sialophosphoprotein | 0.0800028 |
| RPL3 | ribosomal protein L3 | 0.0782217 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0761269 |
| OGA | O-GlcNAcase | 0.0760671 |
| FAT1 | FAT atypical cadherin 1 | 0.076034 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0723654 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0710732 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0684835 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0684294 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.067089 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0663519 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0651899 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0647611 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0637515 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0636092 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0628767 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0626614 |
| FLNB | filamin B, beta | 0.0615931 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0598563 |
| CTBP2 | C-terminal binding protein 2 | 0.0592051 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0591736 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0587929 |
| SLMAP | sarcolemma associated protein | 0.0587606 |
| COL5A2 | collagen, type V, alpha 2 | 0.0584662 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0577455 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0567417 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0564639 |
| HDLBP | high density lipoprotein binding protein | 0.0559618 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0555136 |
| GRB10 | growth factor receptor-bound protein 10 | 0.055441 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0547918 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0541711 |
| RBM39 | RNA binding motif protein 39 | 0.0539788 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0538441 |
| MYO10 | myosin X | 0.0535408 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0531709 |
| OXSR1 | oxidative stress responsive 1 | 0.0529649 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0523511 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0517341 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0514579 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0511774 |
| MYO1E | myosin IE | 0.0500989 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0491752 |
| ASPH | aspartate beta-hydroxylase | 0.0477102 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0469964 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0461992 |
| USP34 | ubiquitin specific peptidase 34 | 0.0460339 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0457421 |
| PRKCA | protein kinase C, alpha | 0.0455417 |
| EGFR | epidermal growth factor receptor | 0.0451879 |
| DST | dystonin | 0.0451206 |
| SMAD3 | SMAD family member 3 | 0.0448803 |
| SBF2 | SET binding factor 2 | 0.0445056 |
| SPAG9 | sperm associated antigen 9 | 0.0440939 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0434484 |
| VEGFA | vascular endothelial growth factor A | 0.0425881 |
| LDHA | lactate dehydrogenase A | 0.0421895 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0417054 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0415765 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0414405 |
| MYO1D | myosin ID | 0.0412845 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0412005 |
| B2M | beta-2-microglobulin | 0.0409943 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0409423 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0379238 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0370202 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0359144 |
| PCDH9 | protocadherin 9 | 0.0359131 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0358928 |
| SQSTM1 | sequestosome 1 | 0.0357068 |
| PARD3 | par-3 family cell polarity regulator | 0.0353914 |
| CANX | calnexin | 0.034955 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0343739 |
| HDAC4 | histone deacetylase 4 | 0.034305 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0339459 |
| YAP1 | Yes-associated protein 1 | 0.0338395 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0330942 |
| PKM | pyruvate kinase, muscle | 0.0325196 |
| GDA | guanine deaminase | 0.0322273 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0306608 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0306018 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0302456 |
| BPTF | bromodomain PHD finger transcription factor | 0.0296329 |
| CDH13 | cadherin 13 | 0.0292121 |
| EZR | ezrin | 0.0290806 |
| SVIL | supervillin | 0.0287252 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0282998 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0282096 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0280966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140645 |
| PTMA | prothymosin, alpha | -0.112967 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0938155 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0840909 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.073302 |
| RPL11 | ribosomal protein L11 | -0.0725188 |
| JMJD1C | jumonji domain containing 1C | -0.0718155 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0702242 |
| RORA | RAR-related orphan receptor A | -0.0685922 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0682994 |
| RPL35A | ribosomal protein L35a | -0.0682755 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0681736 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0672149 |
| PRPF38B | pre-mRNA processing factor 38B | -0.0634595 |
| RPL37 | ribosomal protein L37 | -0.0614373 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.060641 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0598071 |
| DNER | delta/notch-like EGF repeat containing | -0.0586088 |
| RPS8 | ribosomal protein S8 | -0.057806 |
| ARRDC3 | arrestin domain containing 3 | -0.0574084 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0550407 |
| FRMD5 | FERM domain containing 5 | -0.0539111 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0536751 |
| TXNRD1 | thioredoxin reductase 1 | -0.0533887 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0522215 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0521907 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0519768 |
| SNX9 | sorting nexin 9 | -0.0519194 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0515764 |
| RPS16 | ribosomal protein S16 | -0.0515596 |
| RNF213 | ring finger protein 213 | -0.0513097 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0503154 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0502691 |
| VIM | vimentin | -0.0501577 |
| ERBIN | erbb2 interacting protein | -0.050098 |
| GPC6 | glypican 6 | -0.0499066 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0496813 |
| H3-3B | H3.3 histone B | -0.0492729 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0491839 |
| PHF3 | PHD finger protein 3 | -0.0483151 |
| BBX | bobby sox homolog (Drosophila) | -0.0476341 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0468316 |
| FTL | ferritin, light polypeptide | -0.0463762 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0454316 |
| ATP11A | ATPase, class VI, type 11A | -0.0447746 |
| RPS24 | ribosomal protein S24 | -0.0445432 |
| C1D | C1D nuclear receptor corepressor | -0.0443492 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0438797 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0437569 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0436931 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0435678 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0429057 |
| RPLP1 | ribosomal protein, large, P1 | -0.0426616 |
| TPM4 | tropomyosin 4 | -0.0422451 |
| MATR3 | matrin 3 | -0.0422315 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0411197 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0411149 |
| GOLGA4 | golgin A4 | -0.0405931 |
| FNDC3A | fibronectin type III domain containing 3A | -0.040556 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0400333 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.03992 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0389347 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0386699 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0386557 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0384762 |
| WASF2 | WAS protein family, member 2 | -0.0382263 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0381938 |
| NAV2 | neuron navigator 2 | -0.0381639 |
| VCL | vinculin | -0.0380569 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0374086 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.037387 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0373217 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0361772 |
| RPLP2 | ribosomal protein, large, P2 | -0.0358333 |
| TUT7 | terminal uridylyl transferase 7 | -0.035405 |
| LMO7 | LIM domain 7 | -0.0345441 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0340528 |
| MT2A | metallothionein 2A | -0.0325862 |
| PGK1 | phosphoglycerate kinase 1 | -0.0319088 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0313195 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0303376 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0302185 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0299431 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0299356 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0286532 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0284712 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0279451 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0275571 |
| CCNI | cyclin I | -0.027486 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0274401 |
| SMYD3 | SET and MYND domain containing 3 | -0.0269716 |
| NF1 | neurofibromin 1 | -0.0269046 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0268565 |
| ZNF292 | zinc finger protein 292 | -0.0263688 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0259675 |
| MED13L | mediator complex subunit 13-like | -0.0256794 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0251544 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0250133 |
| MYO5B | myosin VB | -0.0247317 |
| ACTN4 | actinin, alpha 4 | -0.0246515 |
