| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.134865 |
| LDHA | lactate dehydrogenase A | 0.117618 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0987861 |
| RPL3 | ribosomal protein L3 | 0.0770363 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.058376 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0577899 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0552272 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0545272 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0539659 |
| APP | amyloid beta (A4) precursor protein | 0.0533959 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0526476 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0514835 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0495641 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0469799 |
| RIGI | RNA sensor RIG-I | 0.0468283 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0463666 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0409634 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0404863 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0394363 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0376304 |
| MCL1 | myeloid cell leukemia 1 | 0.0374825 |
| EPHA3 | EPH receptor A3 | 0.0367419 |
| FGF13 | fibroblast growth factor 13 | 0.0367282 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0364348 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0349017 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0347932 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0347156 |
| RPS4X | ribosomal protein S4, X-linked | 0.0347142 |
| THBS1 | thrombospondin 1 | 0.0347061 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0338327 |
| EGFR | epidermal growth factor receptor | 0.0314911 |
| SET | SET nuclear proto-oncogene | 0.0314279 |
| PCBP2 | poly(rC) binding protein 2 | 0.0310538 |
| ZNF608 | zinc finger protein 608 | 0.0303596 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0298588 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0298175 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0296154 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0289329 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0288756 |
| COL3A1 | collagen, type III, alpha 1 | 0.0282454 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0280138 |
| CPNE1 | copine I | 0.0279911 |
| MED12L | mediator complex subunit 12-like | 0.0279065 |
| CTPS1 | CTP synthase 1 | 0.0277771 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0277638 |
| FLNA | filamin A, alpha | 0.0275338 |
| CEP250 | centrosomal protein 250kDa | 0.0273434 |
| H1-0 | H1.0 linker histone | 0.0269753 |
| MED13L | mediator complex subunit 13-like | 0.0268292 |
| RPL18A | ribosomal protein L18a | 0.0260633 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0260144 |
| TPM3 | tropomyosin 3 | 0.0258447 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0257065 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0255647 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0251953 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0247126 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0246106 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0242284 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0237849 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0235907 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0235232 |
| NRDC | nardilysin convertase | 0.023447 |
| PLEC | plectin | 0.0233281 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0233 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0230186 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.022981 |
| PDGFC | platelet derived growth factor C | 0.0229277 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0228225 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0223509 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0222792 |
| ATG7 | autophagy related 7 | 0.0221812 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0221647 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0213917 |
| COL1A2 | collagen, type I, alpha 2 | 0.0213787 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0212642 |
| CNTNAP1 | contactin associated protein 1 | 0.0211337 |
| PCM1 | pericentriolar material 1 | 0.0210209 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0209917 |
| FOXP2 | forkhead box P2 | 0.0207907 |
| NBEA | neurobeachin | 0.0207873 |
| DICER1 | dicer 1, ribonuclease type III | 0.0207695 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0207598 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0203916 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0203638 |
| MEF2C | myocyte enhancer factor 2C | 0.0203616 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0203053 |
| SNX13 | sorting nexin 13 | 0.0202715 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0200873 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0199881 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0199815 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198654 |
| RBM5 | RNA binding motif protein 5 | 0.0198319 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0195838 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0195386 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0194544 |
| STK38L | serine/threonine kinase 38 like | 0.0194464 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.019314 |
| ITSN2 | intersectin 2 | 0.0192111 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0191665 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.0190682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.144736 |
| TMSB10 | thymosin beta 10 | -0.142669 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.133384 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121634 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.11673 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.105965 |
| PHIP | pleckstrin homology domain interacting protein | -0.10396 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.103002 |
| PTMA | prothymosin, alpha | -0.0691794 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0687632 |
| PEG10 | paternally expressed 10 | -0.0624623 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0617982 |
| RPS16 | ribosomal protein S16 | -0.060956 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0562699 |
| RPS6 | ribosomal protein S6 | -0.055095 |
| RPLP1 | ribosomal protein, large, P1 | -0.0548635 |
| ACTG1 | actin gamma 1 | -0.0546304 |
| DST | dystonin | -0.0540158 |
| CADM2 | cell adhesion molecule 2 | -0.0539515 |
| GPC3 | glypican 3 | -0.0519498 |
| LRRC4C | leucine rich repeat containing 4C | -0.0515501 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0510008 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0504087 |
| PCDH9 | protocadherin 9 | -0.0477904 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0477232 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0474379 |
| PFN1 | profilin 1 | -0.0467583 |
| RASAL2 | RAS protein activator like 2 | -0.0465059 |
| SNX6 | sorting nexin 6 | -0.0454067 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0451914 |
| NRG1 | neuregulin 1 | -0.0451277 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0451011 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0450304 |
| TENM3 | teneurin transmembrane protein 3 | -0.0445302 |
| TUBA1B | tubulin, alpha 1b | -0.0443742 |
| TUT4 | terminal uridylyl transferase 4 | -0.0443218 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0442809 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0433219 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0432601 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0429652 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0418298 |
| TOX | thymocyte selection-associated high mobility group box | -0.0409151 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0398729 |
| ENAH | enabled homolog (Drosophila) | -0.0398175 |
| ZFR | zinc finger RNA binding protein | -0.0394929 |
| MYO10 | myosin X | -0.0393568 |
| HDAC9 | histone deacetylase 9 | -0.039146 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0389283 |
| ZNF292 | zinc finger protein 292 | -0.0387865 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.03876 |
| SYT1 | synaptotagmin I | -0.0383083 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0381205 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0378247 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0377045 |
| USP53 | ubiquitin specific peptidase 53 | -0.037641 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0375829 |
| SIK2 | salt-inducible kinase 2 | -0.0375731 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0370529 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0369663 |
| RPL35A | ribosomal protein L35a | -0.0367231 |
| SRP54 | signal recognition particle 54kDa | -0.0365751 |
| RBM20 | RNA binding motif protein 20 | -0.0365593 |
| MEIS2 | Meis homeobox 2 | -0.0365503 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0365114 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0363058 |
| MAP4 | microtubule-associated protein 4 | -0.0358766 |
| RPS8 | ribosomal protein S8 | -0.0358384 |
| CDK13 | cyclin-dependent kinase 13 | -0.0358141 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0358087 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0355348 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0355115 |
| TCF12 | transcription factor 12 | -0.0350198 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.034882 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0345668 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0342617 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0341848 |
| ANK2 | ankyrin 2, neuronal | -0.0339107 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0337566 |
| RHEB | Ras homolog enriched in brain | -0.0332926 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0329588 |
| RAD51B | RAD51 paralog B | -0.0329237 |
| SRPK2 | SRSF protein kinase 2 | -0.0328837 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0327999 |
| HMGA2 | high mobility group AT-hook 2 | -0.0326229 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0325402 |
| FAM171B | family with sequence similarity 171, member B | -0.0324419 |
| PLPP1 | phospholipid phosphatase 1 | -0.0324287 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0323985 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0323053 |
| SBF2 | SET binding factor 2 | -0.0321746 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0317764 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0312561 |
| PRELID2 | PRELI domain containing 2 | -0.031238 |
| ZNF217 | zinc finger protein 217 | -0.0309682 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0308532 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0306874 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0305512 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0302726 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0302048 |
| ATXN2 | ataxin 2 | -0.03013 |
