| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artesunate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL3 | ribosomal protein L3 | 0.192916 |
| LDHA | lactate dehydrogenase A | 0.111083 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.107851 |
| VCL | vinculin | 0.0954707 |
| PDGFC | platelet derived growth factor C | 0.0953949 |
| PKM | pyruvate kinase, muscle | 0.0846513 |
| PRELID2 | PRELI domain containing 2 | 0.0758591 |
| HDAC9 | histone deacetylase 9 | 0.0737673 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0732985 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0716133 |
| LOXL3 | lysyl oxidase-like 3 | 0.0681034 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0665532 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.060699 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0601791 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0560712 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0546659 |
| TPM4 | tropomyosin 4 | 0.0518384 |
| MKI67 | marker of proliferation Ki-67 | 0.0496988 |
| TMSB4X | thymosin beta 4, X-linked | 0.0488844 |
| RPS4X | ribosomal protein S4, X-linked | 0.047265 |
| DUSP4 | dual specificity phosphatase 4 | 0.0454494 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0441587 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0405235 |
| MACROD2 | MACRO domain containing 2 | 0.0398635 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.039392 |
| AHNAK | AHNAK nucleoprotein | 0.0390201 |
| GSE1 | Gse1 coiled-coil protein | 0.0376551 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0376141 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0370928 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0363546 |
| UBC | ubiquitin C | 0.0360793 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0357915 |
| ZNF608 | zinc finger protein 608 | 0.0349967 |
| SET | SET nuclear proto-oncogene | 0.0347351 |
| CEP250 | centrosomal protein 250kDa | 0.0346348 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0344214 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0343503 |
| HDGF | hepatoma-derived growth factor | 0.0341016 |
| RPL18A | ribosomal protein L18a | 0.0331297 |
| BMP2K | BMP2 inducible kinase | 0.0326973 |
| TPM3 | tropomyosin 3 | 0.0321274 |
| MYO5C | myosin VC | 0.031961 |
| NPAS2 | neuronal PAS domain protein 2 | 0.031497 |
| PLXNA1 | plexin A1 | 0.0313809 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0311253 |
| EGFR | epidermal growth factor receptor | 0.0309342 |
| TMEM65 | transmembrane protein 65 | 0.0304146 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.029856 |
| SQSTM1 | sequestosome 1 | 0.0295964 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0291926 |
| RHOA | ras homolog family member A | 0.0281156 |
| APP | amyloid beta (A4) precursor protein | 0.0278229 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0274253 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0272735 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0269391 |
| PGK1 | phosphoglycerate kinase 1 | 0.0265211 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0258669 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0257272 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0255813 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0253021 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0247889 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0241637 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0240935 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0240219 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.023604 |
| ENO1 | enolase 1, (alpha) | 0.0233489 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0232838 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0230973 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0228322 |
| GLI2 | GLI family zinc finger 2 | 0.0227017 |
| CPNE1 | copine I | 0.0226973 |
| ADAR | adenosine deaminase, RNA-specific | 0.0226822 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.022654 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0226515 |
| VEGFA | vascular endothelial growth factor A | 0.0226016 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0221716 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0220322 |
| PRKCE | protein kinase C, epsilon | 0.0219402 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0219396 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0218804 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0214431 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0211581 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0210737 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0207104 |
| GOLT1A | golgi transport 1A | 0.0206972 |
| TXNRD1 | thioredoxin reductase 1 | 0.0204288 |
| PRSS23 | protease, serine, 23 | 0.0201876 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0200796 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0200214 |
| TPX2 | TPX2, microtubule-associated | 0.0199374 |
| ZNF337 | zinc finger protein 337 | 0.0197737 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0197382 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0196903 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0196102 |
| FOXP1 | forkhead box P1 | 0.0195117 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0194352 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0194023 |
| INSIG2 | insulin induced gene 2 | 0.019388 |
| SEPTIN9 | septin 9 | 0.0193685 |
| SFTPA2 | surfactant protein A2 | 0.019296 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.200048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.116147 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0964572 |
| RPS6 | ribosomal protein S6 | -0.0913971 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0854456 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.078997 |
| RPL35A | ribosomal protein L35a | -0.0769568 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0702675 |
| EVI5 | ecotropic viral integration site 5 | -0.069647 |
| ZNF292 | zinc finger protein 292 | -0.0674249 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0644734 |
| ACTG1 | actin gamma 1 | -0.0635354 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0629151 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0627591 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.060046 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0598657 |
| RPLP1 | ribosomal protein, large, P1 | -0.0595343 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.058158 |
| RPS19 | ribosomal protein S19 | -0.0575983 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0568299 |
| GOLGA4 | golgin A4 | -0.0560699 |
| S100A6 | S100 calcium binding protein A6 | -0.0549304 |
| RPL12 | ribosomal protein L12 | -0.054814 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0547979 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.054071 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0525212 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0502417 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0491166 |
| RPLP0 | ribosomal protein, large, P0 | -0.0488604 |
| QKI | QKI, KH domain containing, RNA binding | -0.0464384 |
| RPL5 | ribosomal protein L5 | -0.0453821 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0453295 |
| RPS24 | ribosomal protein S24 | -0.0450436 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0449865 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0446548 |
| RPL34 | ribosomal protein L34 | -0.0444712 |
| RPS8 | ribosomal protein S8 | -0.0441181 |
| RPL31 | ribosomal protein L31 | -0.0439961 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0429544 |
| PARD3 | par-3 family cell polarity regulator | -0.042787 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0424179 |
| RPS23 | ribosomal protein S23 | -0.0421609 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0419866 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0417873 |
| RPLP2 | ribosomal protein, large, P2 | -0.0406655 |
| RPL37A | ribosomal protein L37a | -0.0389126 |
| S100A4 | S100 calcium binding protein A4 | -0.0385691 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0384083 |
| RPS29 | ribosomal protein S29 | -0.0381867 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0380008 |
| RBM39 | RNA binding motif protein 39 | -0.037608 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0373396 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0372593 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0368021 |
| NF1 | neurofibromin 1 | -0.0363787 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0361991 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0360486 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0359711 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0356274 |
| S100A9 | S100 calcium binding protein A9 | -0.0340597 |
| PFN1 | profilin 1 | -0.0340464 |
| NFIA | nuclear factor I/A | -0.0337595 |
| RPS25 | ribosomal protein S25 | -0.0332242 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0329108 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0315987 |
| SETD5 | SET domain containing 5 | -0.0313987 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0308922 |
| HMGA1 | high mobility group AT-hook 1 | -0.0307977 |
| TMSB10 | thymosin beta 10 | -0.0307716 |
| RPL36 | ribosomal protein L36 | -0.0307148 |
| RPL26 | ribosomal protein L26 | -0.0305752 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0300406 |
| PRRC2C | proline-rich coiled-coil 2C | -0.029937 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0299204 |
| POTEF | POTE ankyrin domain family, member F | -0.0298528 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0297053 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0292684 |
| ANXA1 | annexin A1 | -0.0289649 |
| WDR43 | WD repeat domain 43 | -0.0289346 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0287143 |
| MSI2 | musashi RNA-binding protein 2 | -0.0286217 |
| THOC2 | THO complex 2 | -0.0284554 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0282732 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0281919 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0281735 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0281531 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0277052 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0274061 |
| HMGB1 | high mobility group box 1 | -0.0273267 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.027071 |
| RPL23 | ribosomal protein L23 | -0.026584 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0264078 |
| S100A10 | S100 calcium binding protein A10 | -0.026302 |
| RPL32 | ribosomal protein L32 | -0.0261713 |
| GPHN | gephyrin | -0.0260271 |
| RPL28 | ribosomal protein L28 | -0.0259558 |
| CCNL1 | cyclin L1 | -0.0254673 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0253988 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0253385 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0252632 |
