| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.181225 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.169633 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.143186 |
| VEGFA | vascular endothelial growth factor A | 0.131887 |
| COL6A3 | collagen, type VI, alpha 3 | 0.114454 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0835542 |
| FLNA | filamin A, alpha | 0.0696764 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.068787 |
| HDAC9 | histone deacetylase 9 | 0.0602641 |
| RPL3 | ribosomal protein L3 | 0.0574103 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0558543 |
| MSN | moesin | 0.055669 |
| VCL | vinculin | 0.0541904 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0506383 |
| CANX | calnexin | 0.0476252 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0449601 |
| RPS4X | ribosomal protein S4, X-linked | 0.0445025 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0438405 |
| CEP250 | centrosomal protein 250kDa | 0.0421185 |
| PLIN2 | perilipin 2 | 0.0378263 |
| MCL1 | myeloid cell leukemia 1 | 0.0375392 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0374455 |
| ACTN1 | actinin, alpha 1 | 0.0365474 |
| GLIS3 | GLIS family zinc finger 3 | 0.0350718 |
| FLNB | filamin B, beta | 0.0349715 |
| NABP1 | nucleic acid binding protein 1 | 0.0333771 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0331865 |
| BRD2 | bromodomain containing 2 | 0.0326246 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0318509 |
| RND3 | Rho family GTPase 3 | 0.0316976 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0306843 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0298903 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0298502 |
| RPL18A | ribosomal protein L18a | 0.0293799 |
| INTS6 | integrator complex subunit 6 | 0.0293442 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0290375 |
| ATXN1 | ataxin 1 | 0.0288996 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0273694 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0271119 |
| COL5A1 | collagen, type V, alpha 1 | 0.027013 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0265548 |
| HMGA2 | high mobility group AT-hook 2 | 0.026135 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0260679 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0257659 |
| MLPH | melanophilin | 0.0254858 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0252284 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0250404 |
| APP | amyloid beta (A4) precursor protein | 0.0246592 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.024291 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0241239 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0239436 |
| TUT7 | terminal uridylyl transferase 7 | 0.0237782 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0234505 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0233107 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.022864 |
| C3 | complement component 3 | 0.0227279 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0225527 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0223905 |
| CPNE1 | copine I | 0.0223418 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0217695 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0216362 |
| PCBP2 | poly(rC) binding protein 2 | 0.0209631 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0203499 |
| PLEC | plectin | 0.0203417 |
| YTHDC1 | YTH domain containing 1 | 0.0201227 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0197309 |
| SDC4 | syndecan 4 | 0.0188557 |
| RPL13A | ribosomal protein L13a | 0.0188514 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0186487 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0184513 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0183411 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0178016 |
| ERBIN | erbb2 interacting protein | 0.0177024 |
| COPA | coatomer protein complex, subunit alpha | 0.0176576 |
| EGR1 | early growth response 1 | 0.0175502 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0173951 |
| GTPBP2 | GTP binding protein 2 | 0.0173911 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0170792 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0169834 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0169265 |
| JUN | jun proto-oncogene | 0.0166811 |
| ADORA2B | adenosine A2b receptor | 0.0166757 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0166559 |
| SMAD3 | SMAD family member 3 | 0.016348 |
| TRIM55 | tripartite motif containing 55 | 0.0163473 |
| TSPYL2 | TSPY-like 2 | 0.0162419 |
| SET | SET nuclear proto-oncogene | 0.0162389 |
| OPTN | optineurin | 0.0162303 |
| LASP1 | LIM and SH3 protein 1 | 0.0161342 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0160467 |
| SEPTIN9 | septin 9 | 0.0159782 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.015894 |
| FLCN | folliculin | 0.0158037 |
| PRSS23 | protease, serine, 23 | 0.0155112 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0155106 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.015509 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0154614 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0152039 |
| TUFT1 | tuftelin 1 | 0.0149523 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0149178 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.245948 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.160965 |
| IER3 | immediate early response 3 | -0.100974 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0972052 |
| RPS6 | ribosomal protein S6 | -0.0952287 |
| FN1 | fibronectin 1 | -0.0947267 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0833954 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0762674 |
| HLA-B | major histocompatibility complex, class I, B | -0.0760823 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0746579 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0736576 |
| TMSB10 | thymosin beta 10 | -0.0681492 |
| PDE10A | phosphodiesterase 10A | -0.0659191 |
| PTMA | prothymosin, alpha | -0.0644938 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0642869 |
| B2M | beta-2-microglobulin | -0.0626016 |
| FRMD4A | FERM domain containing 4A | -0.0625025 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.060804 |
| FTL | ferritin, light polypeptide | -0.0605806 |
| RPS8 | ribosomal protein S8 | -0.0600678 |
| ZNF292 | zinc finger protein 292 | -0.059383 |
| RPS24 | ribosomal protein S24 | -0.0587156 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0584215 |
| CADM1 | cell adhesion molecule 1 | -0.0583996 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0582089 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0547056 |
| RAI14 | retinoic acid induced 14 | -0.0544707 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0529731 |
| RPL36A | ribosomal protein L36a | -0.0515828 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0512474 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0487739 |
| RPLP2 | ribosomal protein, large, P2 | -0.0485425 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0476957 |
| MT2A | metallothionein 2A | -0.0473322 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0465768 |
| CD44 | CD44 molecule (Indian blood group) | -0.044988 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0443826 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.044295 |
| PGK1 | phosphoglycerate kinase 1 | -0.0442135 |
| RPL26 | ribosomal protein L26 | -0.0431066 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0423239 |
| TMSB4X | thymosin beta 4, X-linked | -0.0421851 |
| RPS23 | ribosomal protein S23 | -0.0413472 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0408981 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0408613 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0407949 |
| RPS2 | ribosomal protein S2 | -0.0401224 |
| CDCP1 | CUB domain containing protein 1 | -0.0388632 |
| RPLP1 | ribosomal protein, large, P1 | -0.038423 |
| RPS12 | ribosomal protein S12 | -0.0376824 |
| RPL32 | ribosomal protein L32 | -0.0370596 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0368082 |
| ATP13A3 | ATPase type 13A3 | -0.03614 |
| TKT | transketolase | -0.0360186 |
| RPL23 | ribosomal protein L23 | -0.0354443 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0350322 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0338569 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0335322 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0329131 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.032843 |
| RPL12 | ribosomal protein L12 | -0.0328345 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0323919 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0323916 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0321519 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320998 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0317651 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0316339 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0315515 |
| RPL37A | ribosomal protein L37a | -0.0308883 |
| RPS25 | ribosomal protein S25 | -0.0304114 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0303689 |
| SRGN | serglycin | -0.030334 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0303236 |
| ACTG1 | actin gamma 1 | -0.0303222 |
| SPAG9 | sperm associated antigen 9 | -0.030056 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0300093 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.02998 |
| ANLN | anillin, actin binding protein | -0.0298526 |
| RPS3 | ribosomal protein S3 | -0.0297152 |
| RPL38 | ribosomal protein L38 | -0.0296554 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0295724 |
| FRMD5 | FERM domain containing 5 | -0.0295587 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0295111 |
| RPL35 | ribosomal protein L35 | -0.0294673 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0292319 |
| RPLP0 | ribosomal protein, large, P0 | -0.0285507 |
| RPS13 | ribosomal protein S13 | -0.0282607 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0281551 |
| RPL36 | ribosomal protein L36 | -0.0280531 |
| SBF2 | SET binding factor 2 | -0.0280342 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0279643 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0279529 |
| NAV2 | neuron navigator 2 | -0.0275149 |
| RPL27A | ribosomal protein L27a | -0.0274549 |
| STC1 | stanniocalcin 1 | -0.0272735 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0269914 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0269001 |
| CLTC | clathrin, heavy chain (Hc) | -0.0267421 |
| RPL5 | ribosomal protein L5 | -0.0265681 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0265145 |
