| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.121888 |
| SQSTM1 | sequestosome 1 | 0.0836104 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0743801 |
| CANX | calnexin | 0.0730355 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0727901 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.070873 |
| SMAD3 | SMAD family member 3 | 0.0695392 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0669395 |
| PLEC | plectin | 0.0651766 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0643606 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0640236 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0606033 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0595006 |
| FLNA | filamin A, alpha | 0.0591811 |
| MCL1 | myeloid cell leukemia 1 | 0.0573894 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0570615 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0551252 |
| FMNL2 | formin-like 2 | 0.0549513 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0507477 |
| SET | SET nuclear proto-oncogene | 0.0470262 |
| SVIL | supervillin | 0.0469988 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0463981 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0457084 |
| ANXA2 | annexin A2 | 0.045199 |
| ERBIN | erbb2 interacting protein | 0.0451841 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.045092 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.045027 |
| CPNE1 | copine I | 0.0442642 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0436954 |
| BRD2 | bromodomain containing 2 | 0.0433838 |
| MSN | moesin | 0.0421915 |
| CAPRIN2 | caprin family member 2 | 0.0415793 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0411999 |
| SATB2 | SATB homeobox 2 | 0.0406603 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0398007 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0393936 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0392851 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.038461 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0384451 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0383042 |
| SPAG9 | sperm associated antigen 9 | 0.0380642 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0378531 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0372669 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0364613 |
| MAP1B | microtubule-associated protein 1B | 0.0357144 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0353614 |
| CD44 | CD44 molecule (Indian blood group) | 0.0350636 |
| NPTN | neuroplastin | 0.035018 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.035002 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0349525 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0345452 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.034413 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0342476 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0341288 |
| RPL3 | ribosomal protein L3 | 0.034115 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0340824 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.033227 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0331506 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0331171 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.032471 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0319533 |
| LMO7 | LIM domain 7 | 0.0319228 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0313345 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0310634 |
| TNPO1 | transportin 1 | 0.0310547 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0304917 |
| PHF20 | PHD finger protein 20 | 0.0303543 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0302691 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0301792 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0298897 |
| PHF3 | PHD finger protein 3 | 0.0298637 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0294747 |
| H1-4 | H1.4 linker histone, cluster member | 0.0294431 |
| ZNF638 | zinc finger protein 638 | 0.0291428 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0288069 |
| CYTH1 | cytohesin 1 | 0.0287751 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0285766 |
| RRBP1 | ribosome binding protein 1 | 0.0282366 |
| WDR43 | WD repeat domain 43 | 0.0280834 |
| TMEM245 | transmembrane protein 245 | 0.0277616 |
| TFG | TRK-fused gene | 0.027481 |
| IPO7 | importin 7 | 0.0274703 |
| UBQLN1 | ubiquilin 1 | 0.0272232 |
| DEK | DEK proto-oncogene | 0.0270465 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.027024 |
| RSF1 | remodeling and spacing factor 1 | 0.0268992 |
| STRBP | spermatid perinuclear RNA binding protein | 0.026807 |
| ECT2 | epithelial cell transforming 2 | 0.026797 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0266141 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0260633 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0259155 |
| CTTN | cortactin | 0.0258173 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.025761 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0256721 |
| ECE1 | endothelin converting enzyme 1 | 0.0256295 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0254725 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0253392 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0251944 |
| GOLGA2 | golgin A2 | 0.025168 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0251287 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.161063 |
| VIM | vimentin | -0.10788 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0888245 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0816121 |
| HMGA2 | high mobility group AT-hook 2 | -0.0697427 |
| TMSB10 | thymosin beta 10 | -0.0648557 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0646378 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0622279 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0517957 |
| YAP1 | Yes-associated protein 1 | -0.0510105 |
| ZNF609 | zinc finger protein 609 | -0.0499237 |
| SBF2 | SET binding factor 2 | -0.0474716 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0462596 |
| EGR1 | early growth response 1 | -0.0451024 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0425206 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0424604 |
| PTMA | prothymosin, alpha | -0.0424357 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0424253 |
| NF1 | neurofibromin 1 | -0.0421366 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0419256 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0413404 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0411621 |
| GPC6 | glypican 6 | -0.0406971 |
| VCL | vinculin | -0.0402424 |
| GLG1 | golgi glycoprotein 1 | -0.0401639 |
| DNER | delta/notch-like EGF repeat containing | -0.039559 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0394219 |
| IGF2 | insulin-like growth factor 2 | -0.0388346 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0387221 |
| TXNIP | thioredoxin interacting protein | -0.0381415 |
| CDK14 | cyclin-dependent kinase 14 | -0.0377052 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0376023 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0371947 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0364707 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0359107 |
| PFN1 | profilin 1 | -0.0357893 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0357029 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0355309 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0351729 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0351628 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0346535 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.034475 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0335464 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0334352 |
| CREBRF | CREB3 regulatory factor | -0.0333742 |
| SMYD3 | SET and MYND domain containing 3 | -0.0333066 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.033142 |
| HDAC9 | histone deacetylase 9 | -0.0331327 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0330879 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0330513 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0328264 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0327341 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0320978 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0320742 |
| S100A9 | S100 calcium binding protein A9 | -0.0317834 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0311433 |
| PCED1B | PC-esterase domain containing 1B | -0.030862 |
| ANGPTL4 | angiopoietin-like 4 | -0.0308433 |
| IL6ST | interleukin 6 signal transducer | -0.030732 |
| NALCN | sodium leak channel, non selective | -0.0304586 |
| RAI14 | retinoic acid induced 14 | -0.0303607 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0300872 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0300138 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0297778 |
| MT2A | metallothionein 2A | -0.0297044 |
| ATXN2 | ataxin 2 | -0.0294807 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0288327 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0285828 |
| TMEM135 | transmembrane protein 135 | -0.028339 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.027989 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0279747 |
| VMP1 | vacuole membrane protein 1 | -0.027904 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.0279009 |
| EEA1 | early endosome antigen 1 | -0.0278669 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0278086 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0277216 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0271819 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0270684 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0268693 |
| MT1X | metallothionein 1X | -0.0267341 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0264714 |
| ZNF438 | zinc finger protein 438 | -0.0264362 |
| RPS13 | ribosomal protein S13 | -0.026351 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0263157 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0263143 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0262582 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0262393 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.02608 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0260622 |
| GOLGA4 | golgin A4 | -0.0258812 |
| RPL37A | ribosomal protein L37a | -0.0257391 |
| RORA | RAR-related orphan receptor A | -0.0257383 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0257313 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0257229 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0256251 |
| PGK1 | phosphoglycerate kinase 1 | -0.0251643 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0250767 |
| HLA-B | major histocompatibility complex, class I, B | -0.0250199 |
| CEP350 | centrosomal protein 350kDa | -0.0249032 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0248855 |
