| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.103058 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0934518 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0848367 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0841808 |
| TMEM156 | transmembrane protein 156 | 0.0670192 |
| VEGFA | vascular endothelial growth factor A | 0.0631525 |
| SMAD3 | SMAD family member 3 | 0.0587491 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0580799 |
| VCL | vinculin | 0.0535057 |
| SEPTIN9 | septin 9 | 0.0525484 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0502961 |
| NRP1 | neuropilin 1 | 0.0502469 |
| SVIL | supervillin | 0.0485449 |
| NTN4 | netrin 4 | 0.0476382 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0427385 |
| MCL1 | myeloid cell leukemia 1 | 0.0404979 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0400094 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.039119 |
| RPL3 | ribosomal protein L3 | 0.0390569 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0384967 |
| GLUL | glutamate-ammonia ligase | 0.0373089 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0368427 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.036358 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0360225 |
| TPM3 | tropomyosin 3 | 0.0336929 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0332635 |
| FLNA | filamin A, alpha | 0.0332025 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0317445 |
| GLIS3 | GLIS family zinc finger 3 | 0.0312938 |
| ADAR | adenosine deaminase, RNA-specific | 0.0307804 |
| TXNRD1 | thioredoxin reductase 1 | 0.0304164 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0300891 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0300606 |
| PELO | pelota homolog (Drosophila) | 0.0298124 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.029251 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0284303 |
| LDHA | lactate dehydrogenase A | 0.0282184 |
| VCAN | versican | 0.027423 |
| MAP1B | microtubule-associated protein 1B | 0.0270668 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0269065 |
| OSMR | oncostatin M receptor | 0.0265653 |
| DUSP5 | dual specificity phosphatase 5 | 0.0262046 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0257871 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0257716 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257023 |
| TOP1 | topoisomerase (DNA) I | 0.0256339 |
| APP | amyloid beta (A4) precursor protein | 0.0255919 |
| RUNX2 | runt-related transcription factor 2 | 0.0253457 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0253185 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0250142 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.02497 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0249386 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.024309 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0242915 |
| NPTN | neuroplastin | 0.0234911 |
| COPA | coatomer protein complex, subunit alpha | 0.0231957 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0229909 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0226299 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0225208 |
| TSPYL2 | TSPY-like 2 | 0.0221737 |
| GPATCH2L | G patch domain containing 2-like | 0.0219579 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.021875 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0216672 |
| MYO10 | myosin X | 0.0216558 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0212714 |
| MSN | moesin | 0.0212626 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0212626 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0212345 |
| BICC1 | BicC family RNA binding protein 1 | 0.0209005 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0208808 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0207969 |
| FHL2 | four and a half LIM domains 2 | 0.0207714 |
| PLEC | plectin | 0.0206013 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0204915 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0204369 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0200999 |
| ATXN1 | ataxin 1 | 0.0199366 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0197459 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0197005 |
| LAMA4 | laminin, alpha 4 | 0.0195853 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0194893 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0194483 |
| ENAH | enabled homolog (Drosophila) | 0.019295 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0191367 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0189775 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.018807 |
| RAB10 | RAB10, member RAS oncogene family | 0.0187804 |
| YBX3 | Y box binding protein 3 | 0.0187599 |
| KSR1 | kinase suppressor of ras 1 | 0.0186372 |
| SSH1 | slingshot protein phosphatase 1 | 0.0185699 |
| ERBIN | erbb2 interacting protein | 0.0184923 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0184378 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0181721 |
| MLPH | melanophilin | 0.0179835 |
| ETV3 | ets variant 3 | 0.0179703 |
| ADORA2B | adenosine A2b receptor | 0.0175495 |
| SGMS2 | sphingomyelin synthase 2 | 0.0173442 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.017293 |
| IL6ST | interleukin 6 signal transducer | 0.0171684 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0171079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.199091 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.173207 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.159055 |
| PTMA | prothymosin, alpha | -0.138101 |
| SQSTM1 | sequestosome 1 | -0.126138 |
| TMSB10 | thymosin beta 10 | -0.102004 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0897662 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0853486 |
| HLA-B | major histocompatibility complex, class I, B | -0.081381 |
| S100A6 | S100 calcium binding protein A6 | -0.0742233 |
| FTL | ferritin, light polypeptide | -0.070537 |
| FN1 | fibronectin 1 | -0.0689719 |
| NRG1 | neuregulin 1 | -0.0682789 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0674444 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0638438 |
| TMSB4X | thymosin beta 4, X-linked | -0.0578399 |
| VIM | vimentin | -0.0539488 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0505546 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0493078 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0488512 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0482932 |
| TMEM165 | transmembrane protein 165 | -0.0479431 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0467464 |
| B2M | beta-2-microglobulin | -0.0457111 |
| IER3 | immediate early response 3 | -0.0452926 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0451671 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0450299 |
| ACTG1 | actin gamma 1 | -0.0448463 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0438363 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0437224 |
| RPL35A | ribosomal protein L35a | -0.043475 |
| ITGA1 | integrin, alpha 1 | -0.0423904 |
| RPL31 | ribosomal protein L31 | -0.0421804 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0417311 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0413106 |
| HMGA2 | high mobility group AT-hook 2 | -0.0403193 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0403171 |
| RPL26 | ribosomal protein L26 | -0.0371113 |
| RPS6 | ribosomal protein S6 | -0.0369554 |
| RAI14 | retinoic acid induced 14 | -0.0366956 |
| RPS29 | ribosomal protein S29 | -0.0359502 |
| RPS8 | ribosomal protein S8 | -0.0353057 |
| RPS24 | ribosomal protein S24 | -0.035293 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0344597 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0341258 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0340175 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0339869 |
| RPL34 | ribosomal protein L34 | -0.0316582 |
| GNAS | GNAS complex locus | -0.0308724 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0307351 |
| NDRG1 | N-myc downstream regulated 1 | -0.0304147 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0304079 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0301226 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0295987 |
| RPL38 | ribosomal protein L38 | -0.0295393 |
| HMGA1 | high mobility group AT-hook 1 | -0.0294296 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.029234 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0284264 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0284214 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0283796 |
| TMEM263 | transmembrane protein 263 | -0.0283471 |
| RACK1 | receptor for activated C kinase 1 | -0.0282493 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0270721 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0270436 |
| RPS27A | ribosomal protein S27a | -0.0266394 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0265847 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.026265 |
| MTDH | metadherin | -0.0262366 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.025634 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0253838 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0251704 |
| RPLP1 | ribosomal protein, large, P1 | -0.0251501 |
| RPS25 | ribosomal protein S25 | -0.0250022 |
| RPL37A | ribosomal protein L37a | -0.0246906 |
| SPAG9 | sperm associated antigen 9 | -0.0246197 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0244207 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0243016 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0239134 |
| RPL36 | ribosomal protein L36 | -0.0236917 |
| CADM1 | cell adhesion molecule 1 | -0.0235796 |
| DENND4C | DENN/MADD domain containing 4C | -0.0232825 |
| RPS21 | ribosomal protein S21 | -0.0228446 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0227992 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0225614 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0222946 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0222052 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0220366 |
| RPLP2 | ribosomal protein, large, P2 | -0.0219481 |
| WDR45B | WD repeat domain 45B | -0.0216423 |
| S100A10 | S100 calcium binding protein A10 | -0.0214799 |
| RTN3 | reticulon 3 | -0.0212871 |
| PLIN2 | perilipin 2 | -0.0212603 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0212166 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.021179 |
| FAM20C | family with sequence similarity 20, member C | -0.0211745 |
| SLC38A1 | solute carrier family 38, member 1 | -0.02104 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0208984 |
| CENPF | centromere protein F, 350/400kDa | -0.0208539 |
| RPL30 | ribosomal protein L30 | -0.0205826 |
| CEP350 | centrosomal protein 350kDa | -0.0205788 |