Asbestosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A pneumoconiosis caused by inhalation and retention of asbestos fibers. (Human Disease Ontology, DOID_10320)
External Link https://www.disgenet.org/browser/0/1/0/C0003949
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Genes

46 genes associated with the disease Asbestosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ARG1 arginase 1
ATF6 activating transcription factor 6
CAT catalase
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
GRAP2 GRB2-related adaptor protein 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HMGB1 high mobility group box 1
HPGDS hematopoietic prostaglandin D synthase
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL1B interleukin 1, beta
LYPD4 LY6/PLAUR domain containing 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSLN mesothelin
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOX4 NADPH oxidase 4
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPD surfactant protein D
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
TNF tumor necrosis factor
TPM4 tropomyosin 4
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1