Ascariasis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A parasitic helminthiasis infectious disease that involves infection of the intestine with the nematode Ascaris lumbricoides. Larvae migrating through the lungs cause cough, wheezing and hemoptysis. Bowel or biliary obstruction causes cramping abdominal pain, nausea, and vomiting. Peritonitis, enlargement of the liver or spleen, toxicity and pneumonia are observed when larvae get into the portal circulation. (Human Disease Ontology, DOID_456)
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Genes

66 genes co-occuring with the disease Ascariasis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ASCL3 achaete-scute family bHLH transcription factor 3 2.341
IL5 interleukin 5 2.216
IL4 interleukin 4 2.098
ASCL5 achaete-scute family bHLH transcription factor 5 2.071
IL10 interleukin 10 2.032
IL13 interleukin 13 2.001
IFT57 intraflagellar transport 57 1.843
IFNG interferon, gamma 1.829
COPS7A COP9 signalosome subunit 7A 1.815
ABHD13 abhydrolase domain containing 13 1.796
CD4 CD4 molecule 1.795
MAGEH1 melanoma antigen family H1 1.753
IL9 interleukin 9 1.605
ALB albumin 1.605
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.542
TNF tumor necrosis factor 1.531
TGFB1 transforming growth factor, beta 1 1.461
IL6 interleukin 6 1.444
EPX eosinophil peroxidase 1.425
IL33 interleukin 33 1.411
CRP C-reactive protein, pentraxin-related 1.398
RNASE3 ribonuclease, RNase A family, 3 1.383
IL2 interleukin 2 1.354
CHIA chitinase, acidic 1.349
PPA1 pyrophosphatase (inorganic) 1 1.339
GHITM growth hormone inducible transmembrane protein 1.337
IL1B interleukin 1, beta 1.33
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.321
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.321
IL17A interleukin 17A 1.318
LIG4 ligase IV, DNA, ATP-dependent 1.294
HPGDS hematopoietic prostaglandin D synthase 1.286
CES2 carboxylesterase 2 1.274
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.271
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.259
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.238
TSLP thymic stromal lymphopoietin 1.235
SLC44A1 solute carrier family 44 (choline transporter), member 1 1.23
FOXP3 forkhead box P3 1.22
CD8A CD8a molecule 1.212
PXDNL peroxidasin-like 1.2
PXDN peroxidasin 1.198
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 1.194
BACE1 beta-site APP-cleaving enzyme 1 1.181
ITLN2 intelectin 2 1.146
GPSM1 G-protein signaling modulator 1 1.145
C8A complement component 8, alpha polypeptide 1.142
CES1 carboxylesterase 1 1.133
PRSS16 protease, serine, 16 (thymus) 1.091
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.081
CCL11 chemokine (C-C motif) ligand 11 1.075
UNC50 unc-50 homolog (C. elegans) 1.072
DACH2 dachshund family transcription factor 2 1.07
SOX3 SRY (sex determining region Y)-box 3 1.064
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.061
TLR4 toll-like receptor 4 1.054
RELT RELT tumor necrosis factor receptor 1.053
ACE2 angiotensin I converting enzyme 2 1.051
TLR2 toll-like receptor 2 1.043
CTSL cathepsin L 1.035
FIP1L1 factor interacting with PAPOLA and CPSF1 1.032
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 1.029
C22ORF39 chromosome 22 open reading frame 39 1.023
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1.017
TBL1X transducin (beta)-like 1X-linked 1.004
CTSB cathepsin B 1.001