| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Asciminib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Asciminib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PGK1 | phosphoglycerate kinase 1 | 0.0692527 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0567175 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0554621 |
| TMSB4X | thymosin beta 4, X-linked | 0.0513798 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0481326 |
| ANLN | anillin, actin binding protein | 0.0475189 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0451986 |
| OGA | O-GlcNAcase | 0.0450424 |
| KRT17 | keratin 17, type I | 0.0431737 |
| MEF2A | myocyte enhancer factor 2A | 0.0413475 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0403961 |
| RBM39 | RNA binding motif protein 39 | 0.04021 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0393471 |
| ENO1 | enolase 1, (alpha) | 0.0393429 |
| SUCO | SUN domain containing ossification factor | 0.0388005 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0382042 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0376725 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0369101 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0366587 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.03624 |
| SPAG9 | sperm associated antigen 9 | 0.0356111 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0353921 |
| SMAD3 | SMAD family member 3 | 0.0353363 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0352931 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0348955 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0338254 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0337171 |
| SERINC3 | serine incorporator 3 | 0.0323262 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0316605 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0316286 |
| RLF | rearranged L-myc fusion | 0.0312024 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0305833 |
| NUP58 | nucleoporin 58 | 0.0302659 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0295803 |
| DIDO1 | death inducer-obliterator 1 | 0.0295383 |
| SLMAP | sarcolemma associated protein | 0.0281956 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0281166 |
| ZNF292 | zinc finger protein 292 | 0.0279644 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0277518 |
| MATR3 | matrin 3 | 0.0277038 |
| ARRDC3 | arrestin domain containing 3 | 0.0274162 |
| SDC4 | syndecan 4 | 0.0273492 |
| APP | amyloid beta (A4) precursor protein | 0.0272532 |
| XPO1 | exportin 1 | 0.027209 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0269476 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0264197 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0261676 |
| USP12 | ubiquitin specific peptidase 12 | 0.0258179 |
| CANX | calnexin | 0.0257395 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0254696 |
| TPX2 | TPX2, microtubule-associated | 0.0247573 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0246196 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0236545 |
| KRT6A | keratin 6A, type II | 0.0233455 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0233337 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0232041 |
| TPM3 | tropomyosin 3 | 0.0231653 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0230345 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0221344 |
| USP3 | ubiquitin specific peptidase 3 | 0.0219632 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0217308 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0213754 |
| KRT8 | keratin 8, type II | 0.0212648 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0212336 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0211305 |
| MSN | moesin | 0.0211083 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0208963 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0207297 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0207279 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0206916 |
| AHNAK | AHNAK nucleoprotein | 0.0206462 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0206277 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0203718 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0203575 |
| GOLGA4 | golgin A4 | 0.0198556 |
| PLEC | plectin | 0.0196146 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0195081 |
| RNF145 | ring finger protein 145 | 0.0194621 |
| COPA | coatomer protein complex, subunit alpha | 0.0192952 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0188481 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0186862 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0186621 |
| SLK | STE20-like kinase | 0.0186095 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0184375 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0183834 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0183092 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0182477 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0182129 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0179004 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0178988 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0177525 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.017692 |
| ECT2 | epithelial cell transforming 2 | 0.0176332 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0175874 |
| HELZ | helicase with zinc finger | 0.017567 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.017404 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0171119 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0170778 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0170399 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0170369 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.170328 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.129478 |
| NDRG1 | N-myc downstream regulated 1 | -0.110197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100554 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0948756 |
| DPYD | dihydropyrimidine dehydrogenase | -0.067334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0534407 |
| TMSB10 | thymosin beta 10 | -0.0487005 |
| FLNB | filamin B, beta | -0.0462581 |
| RPS6 | ribosomal protein S6 | -0.044921 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0444985 |
| MT2A | metallothionein 2A | -0.0402303 |
| S100A10 | S100 calcium binding protein A10 | -0.0389538 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0358881 |
| EFNA5 | ephrin-A5 | -0.0355171 |
| FOXP1 | forkhead box P1 | -0.0349159 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0346474 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0339763 |
| MECOM | MDS1 and EVI1 complex locus | -0.0339598 |
| HMGA2 | high mobility group AT-hook 2 | -0.0322731 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0320795 |
| EGR1 | early growth response 1 | -0.0311162 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0309538 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0308965 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0308709 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305613 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0299302 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0299074 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0292636 |
| INTS6 | integrator complex subunit 6 | -0.0290646 |
| RAD51B | RAD51 paralog B | -0.0287967 |
| EXOC4 | exocyst complex component 4 | -0.0287935 |
| RPS8 | ribosomal protein S8 | -0.0287094 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0280973 |
| RPL11 | ribosomal protein L11 | -0.0267542 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0265049 |
| RPLP1 | ribosomal protein, large, P1 | -0.0263495 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0258015 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0255386 |
| SULF1 | sulfatase 1 | -0.0253457 |
| OSMR | oncostatin M receptor | -0.0253088 |
| OXR1 | oxidation resistance 1 | -0.0249078 |
| CMIP | c-Maf inducing protein | -0.024677 |
| RPS14 | ribosomal protein S14 | -0.0240096 |
| FTL | ferritin, light polypeptide | -0.0239978 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.023827 |
| S100A6 | S100 calcium binding protein A6 | -0.023529 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0232947 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0231842 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0229758 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.022871 |
| DGKH | diacylglycerol kinase, eta | -0.0228306 |
| MYADM | myeloid-associated differentiation marker | -0.0226367 |
| PRELID2 | PRELI domain containing 2 | -0.0224162 |
| RPS19 | ribosomal protein S19 | -0.0221798 |
| RPS25 | ribosomal protein S25 | -0.0219677 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0217738 |
| RPL35A | ribosomal protein L35a | -0.0217666 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0216217 |
| IGF2 | insulin-like growth factor 2 | -0.0214319 |
| RPS21 | ribosomal protein S21 | -0.0213763 |
| GOLGB1 | golgin B1 | -0.021326 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0213126 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0210335 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0210108 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0209521 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0209277 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0206441 |
| MYO9A | myosin IXA | -0.0205181 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0205116 |
| EFNB2 | ephrin-B2 | -0.0204553 |
| LAMA5 | laminin, alpha 5 | -0.0203869 |
| RAI14 | retinoic acid induced 14 | -0.0203127 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0201095 |
| RPL28 | ribosomal protein L28 | -0.0201085 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0200778 |
| RPLP2 | ribosomal protein, large, P2 | -0.0200561 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0198341 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0198296 |
| CORO2A | coronin, actin binding protein, 2A | -0.0197785 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0196927 |
| DUSP5 | dual specificity phosphatase 5 | -0.0196003 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0194669 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0194443 |
| PRSS23 | protease, serine, 23 | -0.0194302 |
| EGFR | epidermal growth factor receptor | -0.0193429 |
| RPL34 | ribosomal protein L34 | -0.0192971 |
| CDK6 | cyclin-dependent kinase 6 | -0.0192528 |
| SOX7 | SRY (sex determining region Y)-box 7 | -0.0192263 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0192192 |
| SMYD3 | SET and MYND domain containing 3 | -0.0190727 |
| RPL8 | ribosomal protein L8 | -0.0189945 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0187371 |
| RPLP0 | ribosomal protein, large, P0 | -0.0186512 |
| RPS27 | ribosomal protein S27 | -0.0186422 |
| RPS12 | ribosomal protein S12 | -0.0186258 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0186237 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0185103 |
| TRIM56 | tripartite motif containing 56 | -0.0178568 |
| RIGI | RNA sensor RIG-I | -0.0178345 |
