| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Asciminib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Asciminib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.193077 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.154982 |
| NAV2 | neuron navigator 2 | 0.131857 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.103378 |
| MSN | moesin | 0.0797285 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0748536 |
| SDC4 | syndecan 4 | 0.0718762 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0714078 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.071393 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0668709 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0664539 |
| CADM1 | cell adhesion molecule 1 | 0.0662164 |
| MYOF | myoferlin | 0.0651267 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0597123 |
| GOLGA4 | golgin A4 | 0.0592527 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.058833 |
| JMJD1C | jumonji domain containing 1C | 0.0565559 |
| FNIP1 | folliculin interacting protein 1 | 0.0536708 |
| FMNL2 | formin-like 2 | 0.0480639 |
| OGA | O-GlcNAcase | 0.0447469 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0409515 |
| ADM | adrenomedullin | 0.0408722 |
| RTN4 | reticulon 4 | 0.0396142 |
| FLNB | filamin B, beta | 0.0377195 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0376518 |
| MXI1 | MAX interactor 1, dimerization protein | 0.03754 |
| FOXO3 | forkhead box O3 | 0.0374236 |
| WTAP | Wilms tumor 1 associated protein | 0.0368709 |
| CDK19 | cyclin-dependent kinase 19 | 0.0365223 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0359026 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0354914 |
| ATP13A3 | ATPase type 13A3 | 0.0347866 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0342443 |
| YEATS2 | YEATS domain containing 2 | 0.0341914 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0320402 |
| ARRDC3 | arrestin domain containing 3 | 0.0318715 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0315182 |
| MT2A | metallothionein 2A | 0.0312425 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.030753 |
| CLIC4 | chloride intracellular channel 4 | 0.0306046 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0306031 |
| DSCAM | Down syndrome cell adhesion molecule | 0.030187 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0296861 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0295598 |
| FLOT1 | flotillin 1 | 0.0294712 |
| CEP250 | centrosomal protein 250kDa | 0.0290838 |
| NEK7 | NIMA-related kinase 7 | 0.0288544 |
| APP | amyloid beta (A4) precursor protein | 0.0283777 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0282104 |
| SPAG9 | sperm associated antigen 9 | 0.0281824 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0277051 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0276925 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0276638 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0276198 |
| VEGFA | vascular endothelial growth factor A | 0.0276002 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0275957 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0275541 |
| PCBP2 | poly(rC) binding protein 2 | 0.0274973 |
| SEPTIN9 | septin 9 | 0.0272979 |
| ZNF292 | zinc finger protein 292 | 0.0269314 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0266727 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0265431 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0264102 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0262957 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0262581 |
| SNX9 | sorting nexin 9 | 0.0255405 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0254582 |
| CCNL1 | cyclin L1 | 0.0253415 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0250076 |
| USP47 | ubiquitin specific peptidase 47 | 0.0249213 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0246726 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0246433 |
| FAM219A | family with sequence similarity 219, member A | 0.0245986 |
| VMP1 | vacuole membrane protein 1 | 0.0245919 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0243861 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0243839 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0243091 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0242514 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.02418 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0241648 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0241326 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0237078 |
| NOTCH2 | notch 2 | 0.0235367 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0235111 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0234525 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0231737 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.023165 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0231234 |
| PGM3 | phosphoglucomutase 3 | 0.0231198 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0230078 |
| ANXA5 | annexin A5 | 0.0229666 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0229625 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.022958 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0229255 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0228006 |
| CENPC | centromere protein C | 0.0227115 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0227108 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0226798 |
| SBF2 | SET binding factor 2 | 0.0222579 |
| EVC | Ellis van Creveld protein | 0.0220237 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GLIS3 | GLIS family zinc finger 3 | -0.205281 |
| VIM | vimentin | -0.193621 |
| BICC1 | BicC family RNA binding protein 1 | -0.177966 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.106204 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.099376 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0923298 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0803179 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0801189 |
| HMGA2 | high mobility group AT-hook 2 | -0.0789672 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0771008 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0742213 |
| VCL | vinculin | -0.0711072 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.060045 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0582575 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0581611 |
| KYNU | kynureninase | -0.0552406 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0539779 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0525317 |
| RNF213 | ring finger protein 213 | -0.0518299 |
| LDHA | lactate dehydrogenase A | -0.0502471 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0502069 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0481548 |
| FTL | ferritin, light polypeptide | -0.0472293 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0471701 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0460551 |
| HLA-A | major histocompatibility complex, class I, A | -0.045939 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0448711 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0445112 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0436031 |
| SMAD3 | SMAD family member 3 | -0.043555 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0434051 |
| CD44 | CD44 molecule (Indian blood group) | -0.0421642 |
| QKI | QKI, KH domain containing, RNA binding | -0.0414828 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.041262 |
| RIGI | RNA sensor RIG-I | -0.0409846 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0409587 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0409222 |
| CDH13 | cadherin 13 | -0.0407867 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0405724 |
| ASPH | aspartate beta-hydroxylase | -0.0404567 |
| TMSB10 | thymosin beta 10 | -0.0403283 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0397472 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0386775 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0383635 |
| VCAN | versican | -0.0376062 |
| PGK1 | phosphoglycerate kinase 1 | -0.0354649 |
| EHBP1 | EH domain binding protein 1 | -0.0351429 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0348892 |
| CANX | calnexin | -0.0347294 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0345554 |
| AHNAK | AHNAK nucleoprotein | -0.0339336 |
| FOXP1 | forkhead box P1 | -0.0338669 |
| PMP22 | peripheral myelin protein 22 | -0.0338504 |
| IER3 | immediate early response 3 | -0.0335961 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0326843 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0326603 |
| HLA-E | major histocompatibility complex, class I, E | -0.0326471 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0325912 |
| DIAPH2 | diaphanous-related formin 2 | -0.0324783 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0323872 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0314893 |
| HLA-B | major histocompatibility complex, class I, B | -0.0313823 |
| TRIM55 | tripartite motif containing 55 | -0.0313387 |
| FN1 | fibronectin 1 | -0.0311129 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0309364 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0306924 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0302646 |
| PALLD | palladin, cytoskeletal associated protein | -0.0299048 |
| NF1 | neurofibromin 1 | -0.0298338 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0295621 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0292653 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0289016 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0286079 |
| EGR1 | early growth response 1 | -0.0285148 |
| GNAS | GNAS complex locus | -0.0280814 |
| RAI14 | retinoic acid induced 14 | -0.028014 |
| SP100 | SP100 nuclear antigen | -0.0275037 |
| XAF1 | XIAP associated factor 1 | -0.0272259 |
| ANXA2 | annexin A2 | -0.0270253 |
| ATG7 | autophagy related 7 | -0.0268956 |
| CTSD | cathepsin D | -0.0268669 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0268115 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0265103 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0263018 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0261595 |
| RRBP1 | ribosome binding protein 1 | -0.0257758 |
| RPS8 | ribosomal protein S8 | -0.0257594 |
| NRP1 | neuropilin 1 | -0.02563 |
| EXOC4 | exocyst complex component 4 | -0.0255031 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0254029 |
| PLSCR1 | phospholipid scramblase 1 | -0.0253126 |
| CNTN6 | contactin 6 | -0.0250207 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0248533 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0247969 |
| WFDC10B | WAP four-disulfide core domain 10B | -0.0243319 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0242453 |
| LOX | lysyl oxidase | -0.024192 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0240061 |
| NABP1 | nucleic acid binding protein 1 | -0.0239552 |
| TNS3 | tensin 3 | -0.0239461 |
