| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Asciminib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Asciminib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.147862 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.115342 |
| SDC4 | syndecan 4 | 0.0954377 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0856205 |
| FAM13A | family with sequence similarity 13, member A | 0.0802382 |
| ATP13A3 | ATPase type 13A3 | 0.074727 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0701678 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0697809 |
| CD44 | CD44 molecule (Indian blood group) | 0.0685846 |
| CALD1 | caldesmon 1 | 0.0668641 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0658739 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0657925 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0574881 |
| THBS1 | thrombospondin 1 | 0.0571888 |
| PGK1 | phosphoglycerate kinase 1 | 0.0557363 |
| SPAG9 | sperm associated antigen 9 | 0.0527042 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0517792 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0502307 |
| FMNL2 | formin-like 2 | 0.0481146 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0479387 |
| MORF4L2 | mortality factor 4 like 2 | 0.0473398 |
| MEF2A | myocyte enhancer factor 2A | 0.0472156 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0461778 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0455422 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0455119 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0452896 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0451136 |
| RPL11 | ribosomal protein L11 | 0.0444464 |
| RPS8 | ribosomal protein S8 | 0.0438479 |
| PCBP2 | poly(rC) binding protein 2 | 0.04333 |
| NUP58 | nucleoporin 58 | 0.0426887 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0423954 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0419524 |
| NRXN3 | neurexin 3 | 0.0413114 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0411109 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.040926 |
| VIM | vimentin | 0.0407654 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0406165 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0405906 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0402521 |
| ARRDC3 | arrestin domain containing 3 | 0.040252 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0402179 |
| MPZL1 | myelin protein zero-like 1 | 0.0384875 |
| RPL12 | ribosomal protein L12 | 0.0383827 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0378665 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0372396 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0370751 |
| ZNF395 | zinc finger protein 395 | 0.0353943 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0353772 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0349475 |
| DST | dystonin | 0.0348898 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.0348114 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0342708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0341753 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0341638 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0339153 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0338518 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0336442 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0331866 |
| CD47 | CD47 molecule | 0.0331592 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0329934 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0327834 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0326841 |
| WTAP | Wilms tumor 1 associated protein | 0.0326055 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0318699 |
| MORF4L1 | mortality factor 4 like 1 | 0.0317561 |
| AHR | aryl hydrocarbon receptor | 0.0312722 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0311919 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.031118 |
| GPATCH8 | G patch domain containing 8 | 0.0309309 |
| ANXA2 | annexin A2 | 0.0309225 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0305465 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0305031 |
| MED13L | mediator complex subunit 13-like | 0.0302912 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0301749 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0299399 |
| RTN4 | reticulon 4 | 0.0295093 |
| SNX9 | sorting nexin 9 | 0.0294925 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0294518 |
| ENO1 | enolase 1, (alpha) | 0.0293126 |
| INSIG2 | insulin induced gene 2 | 0.0290814 |
| PRELID2 | PRELI domain containing 2 | 0.0289884 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0288874 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0288144 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0286954 |
| DENND4A | DENN/MADD domain containing 4A | 0.0286051 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0285925 |
| COPA | coatomer protein complex, subunit alpha | 0.0284303 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0284243 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0283797 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0281826 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0280909 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0278828 |
| OXSR1 | oxidative stress responsive 1 | 0.0277629 |
| JAK1 | Janus kinase 1 | 0.0275898 |
| RAB8B | RAB8B, member RAS oncogene family | 0.027539 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0274692 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0273933 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0273908 |
| ADM | adrenomedullin | 0.027261 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.149001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133593 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126973 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0855431 |
| NDRG1 | N-myc downstream regulated 1 | -0.0797832 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0773823 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0691923 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0679514 |
| MAP1B | microtubule-associated protein 1B | -0.0598642 |
| EFNA5 | ephrin-A5 | -0.0564354 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0537841 |
| CALR | calreticulin | -0.0507352 |
| TXNIP | thioredoxin interacting protein | -0.0465239 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0435573 |
| FTL | ferritin, light polypeptide | -0.0430792 |
| COL1A2 | collagen, type I, alpha 2 | -0.0430203 |
| RPL28 | ribosomal protein L28 | -0.0425918 |
| ACTG1 | actin gamma 1 | -0.0413856 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0409651 |
| CDH13 | cadherin 13 | -0.0393343 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0379071 |
| CCNI | cyclin I | -0.0376261 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0376145 |
| CADM1 | cell adhesion molecule 1 | -0.0373935 |
| IL6 | interleukin 6 | -0.0372962 |
| RRBP1 | ribosome binding protein 1 | -0.0372773 |
| CDK13 | cyclin-dependent kinase 13 | -0.0366418 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0355424 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0353995 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0353241 |
| BSG | basigin (Ok blood group) | -0.0346996 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.034618 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0342888 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0339808 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0335994 |
| USP34 | ubiquitin specific peptidase 34 | -0.0332546 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0330992 |
| HLA-A | major histocompatibility complex, class I, A | -0.0329052 |
| MSN | moesin | -0.0323348 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0322571 |
| RPLP1 | ribosomal protein, large, P1 | -0.0315901 |
| THOC2 | THO complex 2 | -0.031475 |
| EGR1 | early growth response 1 | -0.0313166 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0309448 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.030627 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0305358 |
| DSTN | destrin (actin depolymerizing factor) | -0.0305225 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0302809 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0299239 |
| CMIP | c-Maf inducing protein | -0.0299015 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0298444 |
| HMGA2 | high mobility group AT-hook 2 | -0.0295943 |
| WASF2 | WAS protein family, member 2 | -0.0295659 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0290838 |
| RPS21 | ribosomal protein S21 | -0.029025 |
| UBXN4 | UBX domain protein 4 | -0.0289802 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0289385 |
| SEC24D | SEC24 family member D | -0.0288649 |
| PFN1 | profilin 1 | -0.0287396 |
| NKTR | natural killer cell triggering receptor | -0.0285679 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0281582 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0278961 |
| LDHA | lactate dehydrogenase A | -0.0277436 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0277433 |
| SEPTIN7 | septin 7 | -0.0276142 |
| EGFR | epidermal growth factor receptor | -0.0273559 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0272984 |
| FTO | fat mass and obesity associated | -0.0272572 |
| DIAPH3 | diaphanous-related formin 3 | -0.0271506 |
| SRP72 | signal recognition particle 72kDa | -0.0269335 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0269202 |
| PTMA | prothymosin, alpha | -0.0268255 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0268197 |
| MYADM | myeloid-associated differentiation marker | -0.0264899 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0261015 |
| TMEM165 | transmembrane protein 165 | -0.0260517 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0260029 |
| TMEM167A | transmembrane protein 167A | -0.0259844 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0258957 |
| RPS6 | ribosomal protein S6 | -0.0257923 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0257883 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0257869 |
| FOSL1 | FOS-like antigen 1 | -0.0256054 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0254636 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0254135 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0253348 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0253231 |
| MRC2 | mannose receptor, C type 2 | -0.0253221 |
| TPM1 | tropomyosin 1 (alpha) | -0.0252732 |
| ACTN1 | actinin, alpha 1 | -0.0251804 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0250255 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0249876 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.0247381 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.024528 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0244703 |
| MGLL | monoglyceride lipase | -0.0244254 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0242099 |
| AFF3 | AF4/FMR2 family, member 3 | -0.023829 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0237407 |
| TPX2 | TPX2, microtubule-associated | -0.0236651 |
