| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Asciminib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Asciminib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0938683 |
| SPAG9 | sperm associated antigen 9 | 0.092133 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0707071 |
| NUP58 | nucleoporin 58 | 0.0592418 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0579422 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0564135 |
| TFG | TRK-fused gene | 0.0489327 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0474536 |
| DSCAM | Down syndrome cell adhesion molecule | 0.041376 |
| ECT2 | epithelial cell transforming 2 | 0.0412803 |
| RNF145 | ring finger protein 145 | 0.0407395 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0394606 |
| SDC4 | syndecan 4 | 0.0392159 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0392131 |
| TNPO1 | transportin 1 | 0.037355 |
| SNX14 | sorting nexin 14 | 0.0372468 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0355704 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0355618 |
| INSIG1 | insulin induced gene 1 | 0.0343119 |
| SET | SET nuclear proto-oncogene | 0.034162 |
| CUL3 | cullin 3 | 0.0339294 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0338137 |
| QKI | QKI, KH domain containing, RNA binding | 0.032956 |
| HELZ | helicase with zinc finger | 0.0325869 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0325184 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0324728 |
| XPO1 | exportin 1 | 0.0324508 |
| CCNL1 | cyclin L1 | 0.032322 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0315422 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0314654 |
| MORF4L1 | mortality factor 4 like 1 | 0.0314271 |
| MATR3 | matrin 3 | 0.0313418 |
| RHEB | Ras homolog enriched in brain | 0.0306834 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0304195 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0301861 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296542 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0292805 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0292239 |
| NUP153 | nucleoporin 153kDa | 0.0291494 |
| COLEC11 | collectin sub-family member 11 | 0.0289783 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0286181 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.028425 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0283783 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0279521 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0279361 |
| SRP54 | signal recognition particle 54kDa | 0.0279096 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0277278 |
| ZNF292 | zinc finger protein 292 | 0.0276158 |
| WDR43 | WD repeat domain 43 | 0.0276127 |
| PAPOLA | poly(A) polymerase alpha | 0.0275438 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0272551 |
| FAM13B | family with sequence similarity 13, member B | 0.0269769 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0269249 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.026281 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0261835 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0260067 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0259516 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0258569 |
| PCBP2 | poly(rC) binding protein 2 | 0.0255888 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0255627 |
| COPA | coatomer protein complex, subunit alpha | 0.0254805 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.025247 |
| ANXA5 | annexin A5 | 0.0250957 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0246225 |
| TMEM41B | transmembrane protein 41B | 0.0244634 |
| CRY1 | cryptochrome circadian clock 1 | 0.0242903 |
| DIAPH1 | diaphanous-related formin 1 | 0.0242321 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0240165 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0239886 |
| TEX10 | testis expressed 10 | 0.0239699 |
| ATXN2L | ataxin 2-like | 0.023628 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.023544 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0233274 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0233216 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.023313 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0232374 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0232242 |
| OGA | O-GlcNAcase | 0.0229736 |
| SNX2 | sorting nexin 2 | 0.0229539 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0229291 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0228992 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0224939 |
| USP37 | ubiquitin specific peptidase 37 | 0.0224241 |
| MEF2A | myocyte enhancer factor 2A | 0.0223887 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0222658 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0221784 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0217929 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0215373 |
| INSIG2 | insulin induced gene 2 | 0.0210807 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.021074 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0210465 |
| HDAC2 | histone deacetylase 2 | 0.0209698 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.020833 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.020809 |
| FAM13A | family with sequence similarity 13, member A | 0.0206007 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0204848 |
| TTK | TTK protein kinase | 0.0201844 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0201807 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0201166 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0201158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.386752 |
| VIM | vimentin | -0.10631 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0890341 |
| SMYD3 | SET and MYND domain containing 3 | -0.0860635 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0806127 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0754747 |
| OSMR | oncostatin M receptor | -0.0730273 |
| DST | dystonin | -0.0695735 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.068287 |
| ATM | ATM serine/threonine kinase | -0.0678578 |
| TMSB10 | thymosin beta 10 | -0.0628894 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0580795 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0555264 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0532419 |
| USP34 | ubiquitin specific peptidase 34 | -0.0528806 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0521407 |
| CD44 | CD44 molecule (Indian blood group) | -0.0517539 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.051325 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0501254 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0479347 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0467131 |
| FMN1 | formin 1 | -0.0464356 |
| NF1 | neurofibromin 1 | -0.0463385 |
| NAV2 | neuron navigator 2 | -0.0459535 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0435893 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0421261 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0419441 |
| NALCN | sodium leak channel, non selective | -0.0418463 |
| RAD51B | RAD51 paralog B | -0.0408812 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0400474 |
| ACTG1 | actin gamma 1 | -0.0396032 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0394042 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0391576 |
| FNDC3B | fibronectin type III domain containing 3B | -0.038983 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0380516 |
| GOLGA4 | golgin A4 | -0.0376267 |
| FNIP1 | folliculin interacting protein 1 | -0.0376205 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0372024 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0370594 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0365018 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0360969 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0359535 |
| GPHN | gephyrin | -0.0357604 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0356568 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0347589 |
| EXOC4 | exocyst complex component 4 | -0.0345904 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0342402 |
| MYO9A | myosin IXA | -0.0338027 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0334918 |
| BPTF | bromodomain PHD finger transcription factor | -0.0334373 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0333169 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0333118 |
| HMGA2 | high mobility group AT-hook 2 | -0.0332551 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0331526 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0321056 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.031834 |
| GOLGB1 | golgin B1 | -0.0317361 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0312803 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0309409 |
| DIAPH3 | diaphanous-related formin 3 | -0.0309131 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0308529 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0305359 |
| NBEA | neurobeachin | -0.0304176 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0304014 |
| VCL | vinculin | -0.0301688 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0300589 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0299713 |
| YBX3 | Y box binding protein 3 | -0.0299379 |
| AK1 | adenylate kinase 1 | -0.0298303 |
| RANBP17 | RAN binding protein 17 | -0.029696 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0295716 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0292926 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0290127 |
| SVIL | supervillin | -0.0288842 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0288236 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0285934 |
| ANO6 | anoctamin 6 | -0.028454 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0284053 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0283978 |
| RNF213 | ring finger protein 213 | -0.0283407 |
| RPS6 | ribosomal protein S6 | -0.0282125 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0281131 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0281003 |
| PHF14 | PHD finger protein 14 | -0.0278338 |
| METTL15 | methyltransferase like 15 | -0.0277473 |
| AHNAK | AHNAK nucleoprotein | -0.0275176 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0273988 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0273413 |
| RSF1 | remodeling and spacing factor 1 | -0.0273156 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0271059 |
| RIN2 | Ras and Rab interactor 2 | -0.0270183 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0269332 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0268758 |
| CUX1 | cut-like homeobox 1 | -0.0268017 |
| CENPF | centromere protein F, 350/400kDa | -0.0267002 |
| RPLP1 | ribosomal protein, large, P1 | -0.0266116 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.026545 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0265442 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0264493 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0263884 |
