| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Asciminib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Asciminib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.122698 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0950014 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0692584 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0656728 |
| RNF145 | ring finger protein 145 | 0.0505732 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0471429 |
| ETNK1 | ethanolamine kinase 1 | 0.0464772 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0448839 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0446516 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0421518 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.038398 |
| RTN4 | reticulon 4 | 0.0376625 |
| OGA | O-GlcNAcase | 0.037579 |
| NUP58 | nucleoporin 58 | 0.035493 |
| WDR43 | WD repeat domain 43 | 0.0350785 |
| ANXA5 | annexin A5 | 0.0350473 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0347182 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0335744 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0334874 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0334204 |
| FAT1 | FAT atypical cadherin 1 | 0.0331175 |
| YME1L1 | YME1-like 1 ATPase | 0.0330304 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0330119 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0326774 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0326344 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0323581 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0322179 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0318012 |
| NEK7 | NIMA-related kinase 7 | 0.0317454 |
| TFG | TRK-fused gene | 0.0310623 |
| PELO | pelota homolog (Drosophila) | 0.030951 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0308386 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0307235 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0302566 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0299709 |
| APP | amyloid beta (A4) precursor protein | 0.0297887 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0297852 |
| RBM33 | RNA binding motif protein 33 | 0.0293568 |
| TNPO1 | transportin 1 | 0.0289757 |
| EREG | epiregulin | 0.0289103 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.028566 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0284219 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0283888 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0283669 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0282344 |
| WDR45B | WD repeat domain 45B | 0.027991 |
| RLF | rearranged L-myc fusion | 0.0279523 |
| WTAP | Wilms tumor 1 associated protein | 0.0276493 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0271277 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0270502 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0269202 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0264719 |
| GOLGA4 | golgin A4 | 0.026074 |
| TMEM156 | transmembrane protein 156 | 0.0258616 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0258022 |
| USP3 | ubiquitin specific peptidase 3 | 0.0255165 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0247998 |
| CAB39 | calcium binding protein 39 | 0.0244451 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0233629 |
| SMOX | spermine oxidase | 0.0232821 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0231292 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0227507 |
| CCNT2 | cyclin T2 | 0.0227168 |
| RHEB | Ras homolog enriched in brain | 0.0227015 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0226858 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0226583 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0226045 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0222022 |
| PCBP2 | poly(rC) binding protein 2 | 0.021864 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0217822 |
| XPO1 | exportin 1 | 0.0212771 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0211476 |
| PNN | pinin, desmosome associated protein | 0.0211435 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0210887 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.021083 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0210434 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0209333 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0209182 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0207457 |
| SUCO | SUN domain containing ossification factor | 0.0206305 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0205803 |
| DENND5B | DENN/MADD domain containing 5B | 0.0205425 |
| CLINT1 | clathrin interactor 1 | 0.0205348 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0205228 |
| SPOPL | speckle-type POZ protein-like | 0.0205208 |
| CORO1C | coronin, actin binding protein, 1C | 0.0203926 |
| RANBP2 | RAN binding protein 2 | 0.0203055 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.020188 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0201734 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.0201254 |
| ZNF292 | zinc finger protein 292 | 0.0200311 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0198208 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0198075 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0197405 |
| ZFR | zinc finger RNA binding protein | 0.0193635 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.019308 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.019302 |
| FOXJ3 | forkhead box J3 | 0.0192835 |
| VMP1 | vacuole membrane protein 1 | 0.0191466 |
| RAB18 | RAB18, member RAS oncogene family | 0.0191321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.235454 |
| FN1 | fibronectin 1 | -0.179596 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14987 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.142183 |
| NDRG1 | N-myc downstream regulated 1 | -0.131637 |
| HMGA2 | high mobility group AT-hook 2 | -0.130717 |
| EFNA5 | ephrin-A5 | -0.0961201 |
| PTMA | prothymosin, alpha | -0.0881618 |
| GLIS3 | GLIS family zinc finger 3 | -0.078593 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.073175 |
| ASPH | aspartate beta-hydroxylase | -0.0700654 |
| SYT1 | synaptotagmin I | -0.0688992 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0659824 |
| STC2 | stanniocalcin 2 | -0.0654805 |
| FTL | ferritin, light polypeptide | -0.0624747 |
| RAI14 | retinoic acid induced 14 | -0.0618115 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0616006 |
| TMSB10 | thymosin beta 10 | -0.0608033 |
| VIM | vimentin | -0.0603167 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0573624 |
| LMNA | lamin A/C | -0.0572256 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.05636 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0519387 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0477697 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0471358 |
| SQSTM1 | sequestosome 1 | -0.0467172 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0460039 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0449663 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0445077 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0427961 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0413458 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.040713 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0406791 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0400687 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0390823 |
| MT2A | metallothionein 2A | -0.038695 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0379984 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0373846 |
| INTS6 | integrator complex subunit 6 | -0.0372924 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0363835 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0359343 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0354884 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0353164 |
| LOXL2 | lysyl oxidase-like 2 | -0.0350286 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0349604 |
| PLIN2 | perilipin 2 | -0.0346935 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0331864 |
| AEBP2 | AE binding protein 2 | -0.0329947 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0327378 |
| S100A10 | S100 calcium binding protein A10 | -0.031854 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0318323 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0317084 |
| GNAS | GNAS complex locus | -0.0315454 |
| EZR | ezrin | -0.0315297 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0314738 |
| S100A6 | S100 calcium binding protein A6 | -0.0314391 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0313653 |
| FLNB | filamin B, beta | -0.0310676 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0309449 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0305617 |
| TNS3 | tensin 3 | -0.0302404 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0301993 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0301395 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0300875 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.029899 |
| PRKCA | protein kinase C, alpha | -0.0294698 |
| ITGA1 | integrin, alpha 1 | -0.0287371 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0287315 |
| ATXN1 | ataxin 1 | -0.0285769 |
| RAD51B | RAD51 paralog B | -0.0285005 |
| EGFR | epidermal growth factor receptor | -0.0283283 |
| ACTG1 | actin gamma 1 | -0.0281545 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0275213 |
| RPL35A | ribosomal protein L35a | -0.0274472 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0271433 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0265232 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0263505 |
| CTBP2 | C-terminal binding protein 2 | -0.0262253 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0260451 |
| RPS6 | ribosomal protein S6 | -0.025844 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0256125 |
| RASAL2 | RAS protein activator like 2 | -0.0254542 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0252817 |
| EMP1 | epithelial membrane protein 1 | -0.0251161 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0250685 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0247581 |
| CUX1 | cut-like homeobox 1 | -0.0247415 |
| RANBP17 | RAN binding protein 17 | -0.0247183 |
| RPL31 | ribosomal protein L31 | -0.0245767 |
| RNF213 | ring finger protein 213 | -0.0243654 |
| VEGFC | vascular endothelial growth factor C | -0.0243506 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0239784 |
| TGFB1 | transforming growth factor, beta 1 | -0.0239609 |
| HMGA1 | high mobility group AT-hook 1 | -0.0236241 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0234023 |
| USP34 | ubiquitin specific peptidase 34 | -0.0231384 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0230701 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0228743 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0227653 |
| HDLBP | high density lipoprotein binding protein | -0.0226338 |
