Aspiration Pneumonitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A pneumonia that is defined as an acute lung injury after the inhalation of foreign material such as regurgitated acidic gastric contents, petroleum products and laxative oils. This syndrome occurs in patients who have a marked disturbance of consciousness such as that resulting from a drug overdose, seizures, a massive cerebrovascular accident, or the use of anesthesia. Aspiration of gastric contents results in a chemical burn of the tracheobronchial tree and pulmonary parenchyma, causing an intense parenchymal inflammatory reaction. The disesae has_symptom non-productive cough, has_symptom tachypnea, has_symptom bronchospasm, has_symptom bloody sputum, has_symptom frothy sputum, or has_symptom respiratory distress, 2-5 hrs after aspiration. (Human Disease Ontology, DOID_3240)
External Link https://www.disgenet.org/browser/0/1/0/C1761609
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Genes

12 genes associated with the disease Aspiration Pneumonitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ALB albumin
CAT catalase
CRP C-reactive protein, pentraxin-related
DPP4 dipeptidyl-peptidase 4
ESD esterase D
IL1B interleukin 1, beta
KDR kinase insert domain receptor
MECP2 methyl CpG binding protein 2
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NLRP3 NLR family, pyrin domain containing 3
TAC1 tachykinin, precursor 1