| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.191467 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.167152 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.099072 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0719238 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0704777 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0635802 |
| C1D | C1D nuclear receptor corepressor | 0.0456187 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0428828 |
| FBN1 | fibrillin 1 | 0.0417941 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0417304 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0403539 |
| STC1 | stanniocalcin 1 | 0.0403329 |
| UBC | ubiquitin C | 0.037792 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.034444 |
| OPTN | optineurin | 0.0335408 |
| LOXL2 | lysyl oxidase-like 2 | 0.0333015 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0330896 |
| PLAT | plasminogen activator, tissue | 0.032896 |
| SEPTIN9 | septin 9 | 0.0328077 |
| GPC6 | glypican 6 | 0.0323788 |
| FNIP1 | folliculin interacting protein 1 | 0.0321563 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0315534 |
| COL1A2 | collagen, type I, alpha 2 | 0.0304788 |
| VEGFA | vascular endothelial growth factor A | 0.0301318 |
| SBF2 | SET binding factor 2 | 0.0300335 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0294629 |
| CD109 | CD109 molecule | 0.0292234 |
| SFTPA2 | surfactant protein A2 | 0.0275363 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0271302 |
| ATP13A3 | ATPase type 13A3 | 0.0269671 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.026927 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0264721 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0260332 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0251961 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0251307 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0249733 |
| MYADM | myeloid-associated differentiation marker | 0.0246964 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.023618 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0235487 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.023425 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0233954 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0230602 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0230176 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0227605 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0226322 |
| NGLY1 | N-glycanase 1 | 0.0223382 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0217336 |
| FRMD5 | FERM domain containing 5 | 0.0217115 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0215212 |
| COPA | coatomer protein complex, subunit alpha | 0.0215026 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0211688 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0201221 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0200746 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0199587 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0198975 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0196823 |
| TPM3 | tropomyosin 3 | 0.0196508 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0194171 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.019293 |
| ZNF148 | zinc finger protein 148 | 0.0189685 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0186781 |
| COG5 | component of oligomeric golgi complex 5 | 0.0185584 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0184832 |
| MTSS1 | metastasis suppressor 1 | 0.0183094 |
| INSIG2 | insulin induced gene 2 | 0.0182518 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0181235 |
| NOTCH2 | notch 2 | 0.0179237 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0179096 |
| YEATS2 | YEATS domain containing 2 | 0.0178915 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0174815 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0173577 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0169624 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0168056 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0166699 |
| ATL3 | atlastin GTPase 3 | 0.0166561 |
| LRRC49 | leucine rich repeat containing 49 | 0.0165232 |
| MSN | moesin | 0.0164862 |
| FLNB | filamin B, beta | 0.0164634 |
| CEP95 | centrosomal protein 95kDa | 0.0163684 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0162982 |
| TMOD1 | tropomodulin 1 | 0.0162191 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0162039 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0161742 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0161735 |
| AFDN | afadin, adherens junction formation factor | 0.0160782 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0159097 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.015865 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0157934 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0157913 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0156895 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0155321 |
| TMEM165 | transmembrane protein 165 | 0.0155049 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0152967 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0152343 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0151647 |
| MMP12 | matrix metallopeptidase 12 | 0.0151314 |
| EZR | ezrin | 0.0149636 |
| LAMA5 | laminin, alpha 5 | 0.0148417 |
| RHOA | ras homolog family member A | 0.0148269 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0148099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.207619 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.203568 |
| AHNAK | AHNAK nucleoprotein | -0.145021 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.130998 |
| FN1 | fibronectin 1 | -0.107587 |
| RIGI | RNA sensor RIG-I | -0.10287 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.10257 |
| CDH13 | cadherin 13 | -0.101254 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0989465 |
| MAP1B | microtubule-associated protein 1B | -0.098551 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.096333 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0962427 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0944923 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0914243 |
| MT2A | metallothionein 2A | -0.0894642 |
| VIM | vimentin | -0.0872436 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0861727 |
| LMNA | lamin A/C | -0.0837136 |
| S100A10 | S100 calcium binding protein A10 | -0.0833512 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0830004 |
| COL5A1 | collagen, type V, alpha 1 | -0.0799548 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0655241 |
| CANX | calnexin | -0.0642949 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0629699 |
| NAV1 | neuron navigator 1 | -0.0629193 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0628365 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0606117 |
| ASPH | aspartate beta-hydroxylase | -0.0561653 |
| SP100 | SP100 nuclear antigen | -0.0553375 |
| RNF213 | ring finger protein 213 | -0.055209 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0546964 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0524059 |
| HLA-B | major histocompatibility complex, class I, B | -0.0515125 |
| SQSTM1 | sequestosome 1 | -0.0499668 |
| B2M | beta-2-microglobulin | -0.0492052 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0491505 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0480218 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.046277 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.046116 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0454973 |
| FSTL1 | follistatin-like 1 | -0.0452716 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0452112 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0443451 |
| COL5A2 | collagen, type V, alpha 2 | -0.0442392 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0437412 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0424312 |
| RRBP1 | ribosome binding protein 1 | -0.0421092 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0415162 |
| PODXL | podocalyxin-like | -0.0414361 |
| MX2 | MX dynamin-like GTPase 2 | -0.0413258 |
| CAVIN1 | caveolae associated protein 1 | -0.0403578 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.039263 |
| LRRC17 | leucine rich repeat containing 17 | -0.0389918 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.038901 |
| MYOF | myoferlin | -0.0385689 |
| LDHA | lactate dehydrogenase A | -0.0380712 |
| PLXNA2 | plexin A2 | -0.0373523 |
| SEPTIN7 | septin 7 | -0.0368992 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0368057 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0365499 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.036296 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0357999 |
| HLA-C | major histocompatibility complex, class I, C | -0.035633 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0354837 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0352663 |
| PRSS23 | protease, serine, 23 | -0.0352048 |
| PRELID2 | PRELI domain containing 2 | -0.035111 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0350569 |
| TMSB4X | thymosin beta 4, X-linked | -0.0347613 |
| TPM4 | tropomyosin 4 | -0.0347215 |
| IL7R | interleukin 7 receptor | -0.0345048 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0342186 |
| SUCNR1 | succinate receptor 1 | -0.0341782 |
| ACTG1 | actin gamma 1 | -0.0341458 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0341098 |
| PCDH7 | protocadherin 7 | -0.034001 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.033641 |
| ANXA2 | annexin A2 | -0.0329668 |
| PARD3 | par-3 family cell polarity regulator | -0.0324122 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0323486 |
| S100A6 | S100 calcium binding protein A6 | -0.0323217 |
| S100A4 | S100 calcium binding protein A4 | -0.0320989 |
| CDK6 | cyclin-dependent kinase 6 | -0.0317583 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0316872 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0314862 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0314815 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0303921 |
| RPLP1 | ribosomal protein, large, P1 | -0.0300849 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0295357 |
| TAGLN2 | transgelin 2 | -0.0294109 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.029254 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0290693 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0290335 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0290154 |
| RPS8 | ribosomal protein S8 | -0.0289968 |
| RPLP2 | ribosomal protein, large, P2 | -0.0289309 |
| RPL28 | ribosomal protein L28 | -0.0288857 |
| SEC61G | Sec61 gamma subunit | -0.0288362 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0284426 |
| SMYD3 | SET and MYND domain containing 3 | -0.0283959 |
