| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0687955 |
| EHBP1 | EH domain binding protein 1 | 0.0588776 |
| EGR1 | early growth response 1 | 0.035177 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0302835 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0245387 |
| RHOA | ras homolog family member A | 0.0244853 |
| NEBL | nebulette | 0.0228729 |
| GCG | glucagon | 0.0205576 |
| MGAT4C | MGAT4 family, member C | 0.0193318 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0191592 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0182625 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0181685 |
| HLA-A | major histocompatibility complex, class I, A | 0.0171608 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.017107 |
| DACH1 | dachshund family transcription factor 1 | 0.0169448 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0154694 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0145389 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0140443 |
| TGM2 | transglutaminase 2 | 0.013884 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0137958 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0137883 |
| CLDN1 | claudin 1 | 0.0137339 |
| ACLY | ATP citrate lyase | 0.0135941 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0135564 |
| CLIC1 | chloride intracellular channel 1 | 0.0131514 |
| AREG | amphiregulin | 0.012442 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0123873 |
| TSPAN5 | tetraspanin 5 | 0.0123022 |
| KSR2 | kinase suppressor of ras 2 | 0.0121289 |
| RPLP0 | ribosomal protein, large, P0 | 0.0119855 |
| MORF4L1 | mortality factor 4 like 1 | 0.0116719 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0115539 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0112821 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0112432 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0110904 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0108983 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0107699 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0105236 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0105 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 0.0104889 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.0104254 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0102558 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0102517 |
| ANXA2 | annexin A2 | 0.0102176 |
| DUSP16 | dual specificity phosphatase 16 | 0.010199 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0101323 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.00994667 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.00993298 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.00987691 |
| S100A6 | S100 calcium binding protein A6 | 0.00969929 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.00965657 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00962167 |
| R3HDM2 | R3H domain containing 2 | 0.00955152 |
| DTNA | dystrobrevin, alpha | 0.00943181 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00922479 |
| CERT1 | ceramide transporter 1 | 0.00917604 |
| GANAB | glucosidase, alpha; neutral AB | 0.00897682 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.00897657 |
| SLC37A3 | solute carrier family 37, member 3 | 0.00896617 |
| NAV3 | neuron navigator 3 | 0.00896462 |
| FSTL5 | follistatin-like 5 | 0.00896085 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.00889711 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00885625 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0088272 |
| IER2 | immediate early response 2 | 0.00879351 |
| COX19 | COX19 cytochrome c oxidase assembly factor | 0.00876225 |
| KLHDC4 | kelch domain containing 4 | 0.00875689 |
| ETF1 | eukaryotic translation termination factor 1 | 0.0086313 |
| MYPN | myopalladin | 0.00860038 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.00851018 |
| CRY1 | cryptochrome circadian clock 1 | 0.00850301 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00842918 |
| MYO1D | myosin ID | 0.00842749 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.00836003 |
| TAPBP | TAP binding protein (tapasin) | 0.00835266 |
| ANXA4 | annexin A4 | 0.00832932 |
| IQCE | IQ motif containing E | 0.00827792 |
| RNF213 | ring finger protein 213 | 0.00826464 |
| FAM117B | family with sequence similarity 117, member B | 0.00826056 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0082516 |
| EPHA2 | EPH receptor A2 | 0.00823891 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00819853 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00813785 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00793376 |
| CYTH3 | cytohesin 3 | 0.00791373 |
| LIX1L | Lix1 homolog (chicken) like | 0.00791357 |
| TBC1D25 | TBC1 domain family, member 25 | 0.00789656 |
| TFCP2 | transcription factor CP2 | 0.00781216 |
| TMEM94 | transmembrane protein 94 | 0.00780215 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.00779278 |
| TMEM52B | transmembrane protein 52B | 0.00774785 |
| SMIM44 | small integral membrane protein 44 | 0.00774538 |
| VCL | vinculin | 0.00772868 |
| STK10 | serine/threonine kinase 10 | 0.00771712 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00770317 |
| MYH15 | myosin, heavy chain 15 | 0.00770095 |
| METTL25 | methyltransferase like 25 | 0.00767254 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 0.00763739 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.00763488 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00763469 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.154435 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.129894 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.127494 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109486 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0969771 |
| RPS2 | ribosomal protein S2 | -0.0900104 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0885875 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0867495 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0828149 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0825872 |
| TMSB10 | thymosin beta 10 | -0.0759913 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0698698 |
| MMP12 | matrix metallopeptidase 12 | -0.0670056 |
| PTMA | prothymosin, alpha | -0.066596 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.066324 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0645509 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0638789 |
| RRM2 | ribonucleotide reductase M2 | -0.0628657 |
| TXNRD1 | thioredoxin reductase 1 | -0.0621442 |
| YAP1 | Yes-associated protein 1 | -0.0612282 |
| RPS12 | ribosomal protein S12 | -0.0587475 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0582959 |
| FTL | ferritin, light polypeptide | -0.0568976 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0561311 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0548745 |
| RPS8 | ribosomal protein S8 | -0.054857 |
| XPO1 | exportin 1 | -0.0545783 |
| RPS6 | ribosomal protein S6 | -0.0507658 |
| MKI67 | marker of proliferation Ki-67 | -0.0505634 |
| RPL37A | ribosomal protein L37a | -0.0495716 |
| RTN4 | reticulon 4 | -0.0483656 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.047453 |
| ATP11A | ATPase, class VI, type 11A | -0.0463813 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0452991 |
| RPL26 | ribosomal protein L26 | -0.0452295 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0450982 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0448701 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0446027 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.044469 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0436324 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0435527 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0429809 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0426026 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0423294 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0419706 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.040893 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0407772 |
| TMEM41B | transmembrane protein 41B | -0.0405585 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0404676 |
| YBX3 | Y box binding protein 3 | -0.0402531 |
| ACTG1 | actin gamma 1 | -0.0401686 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0392309 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0390992 |
| RPLP2 | ribosomal protein, large, P2 | -0.0384924 |
| RBM39 | RNA binding motif protein 39 | -0.0384602 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0383926 |
| KIF5B | kinesin family member 5B | -0.0382826 |
| RPL11 | ribosomal protein L11 | -0.0381051 |
| ZNF292 | zinc finger protein 292 | -0.0376354 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0375597 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0375348 |
| RPL19 | ribosomal protein L19 | -0.037419 |
| RPL38 | ribosomal protein L38 | -0.0373183 |
| SET | SET nuclear proto-oncogene | -0.0367261 |
| RPL12 | ribosomal protein L12 | -0.0366701 |
| CEP192 | centrosomal protein 192kDa | -0.0364926 |
| CLTC | clathrin, heavy chain (Hc) | -0.0357727 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.035217 |
| CCNL1 | cyclin L1 | -0.0350807 |
| RPS3 | ribosomal protein S3 | -0.0350082 |
| PCM1 | pericentriolar material 1 | -0.0349894 |
| RPL23 | ribosomal protein L23 | -0.0346451 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0342286 |
| RPS29 | ribosomal protein S29 | -0.0340329 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0339316 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0338726 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0334271 |
| CCDC88A | coiled-coil domain containing 88A | -0.0334116 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0329745 |
| YBX1 | Y box binding protein 1 | -0.0328731 |
| RPL34 | ribosomal protein L34 | -0.032101 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0318492 |
| CCND1 | cyclin D1 | -0.031561 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0314793 |
| OGA | O-GlcNAcase | -0.0313715 |
| USP34 | ubiquitin specific peptidase 34 | -0.0311212 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0311021 |
| CANX | calnexin | -0.0309341 |
| TMEM123 | transmembrane protein 123 | -0.030934 |
| WWOX | WW domain containing oxidoreductase | -0.0307206 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0304193 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0301892 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0301549 |
| MATR3 | matrin 3 | -0.0300821 |
| CKAP5 | cytoskeleton associated protein 5 | -0.030068 |
| RPS19 | ribosomal protein S19 | -0.0299068 |
| GPHN | gephyrin | -0.0298795 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0298603 |
| PHIP | pleckstrin homology domain interacting protein | -0.0297221 |
| TPR | translocated promoter region, nuclear basket protein | -0.0295501 |
