| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Aspirin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.12432 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.083664 |
| FAT1 | FAT atypical cadherin 1 | 0.0805726 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0802159 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0789499 |
| ABHD2 | abhydrolase domain containing 2 | 0.0667237 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0665671 |
| IFNGR1 | interferon gamma receptor 1 | 0.0619132 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0592256 |
| TXNIP | thioredoxin interacting protein | 0.0580804 |
| STK24 | serine/threonine kinase 24 | 0.0577729 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0568449 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0503589 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0495186 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0484746 |
| LIMA1 | LIM domain and actin binding 1 | 0.0476197 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0466053 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0465935 |
| RNF149 | ring finger protein 149 | 0.0459177 |
| RNF43 | ring finger protein 43 | 0.0457765 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0450739 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0433159 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0429766 |
| PDZD8 | PDZ domain containing 8 | 0.0404993 |
| YAP1 | Yes-associated protein 1 | 0.0397531 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.03811 |
| IL20RA | interleukin 20 receptor, alpha | 0.0375247 |
| B2M | beta-2-microglobulin | 0.0357174 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0354387 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0348045 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0343246 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.032269 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0309314 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0304608 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0299908 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0289644 |
| POTEF | POTE ankyrin domain family, member F | 0.0288957 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0287541 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0285977 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0285462 |
| ANXA4 | annexin A4 | 0.028448 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0282586 |
| MICU2 | mitochondrial calcium uptake 2 | 0.0274466 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0273168 |
| UBC | ubiquitin C | 0.0272306 |
| CDCP1 | CUB domain containing protein 1 | 0.0266223 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0262081 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0259276 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0258099 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0251489 |
| LCN2 | lipocalin 2 | 0.0250089 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0246417 |
| RBM33 | RNA binding motif protein 33 | 0.0243779 |
| VEGFA | vascular endothelial growth factor A | 0.0243736 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0241861 |
| ZNF148 | zinc finger protein 148 | 0.0240867 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0239669 |
| FNIP1 | folliculin interacting protein 1 | 0.0237978 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0237495 |
| SMAD3 | SMAD family member 3 | 0.0233267 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0230084 |
| ASPH | aspartate beta-hydroxylase | 0.0229332 |
| TPM3 | tropomyosin 3 | 0.0225266 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0219409 |
| DIAPH1 | diaphanous-related formin 1 | 0.0219285 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0215068 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0212895 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0211603 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0211412 |
| PLS1 | plastin 1 | 0.0209622 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0209139 |
| BCL2L1 | BCL2-like 1 | 0.0208718 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0207874 |
| UBL3 | ubiquitin-like 3 | 0.0206849 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0206542 |
| TJP2 | tight junction protein 2 | 0.0206107 |
| SP3 | Sp3 transcription factor | 0.0204039 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0202723 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0202373 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0200909 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.0198729 |
| MAP7 | microtubule-associated protein 7 | 0.0193024 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0192487 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0191858 |
| PGK1 | phosphoglycerate kinase 1 | 0.0191758 |
| MKRN1 | makorin ring finger protein 1 | 0.0190291 |
| SERINC5 | serine incorporator 5 | 0.0190118 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0190036 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0189024 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0187423 |
| LDHA | lactate dehydrogenase A | 0.0184939 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.018453 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0184214 |
| RBM26 | RNA binding motif protein 26 | 0.0184009 |
| RPS8 | ribosomal protein S8 | 0.0181126 |
| NCKAP5 | NCK-associated protein 5 | 0.0180409 |
| CCDC6 | coiled-coil domain containing 6 | 0.0180013 |
| RPS6 | ribosomal protein S6 | 0.017921 |
| EPHB2 | EPH receptor B2 | 0.0177989 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0175903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SQSTM1 | sequestosome 1 | -0.151655 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.146321 |
| INTS6 | integrator complex subunit 6 | -0.139658 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.139205 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132626 |
| RIGI | RNA sensor RIG-I | -0.128914 |
| RNF213 | ring finger protein 213 | -0.128118 |
| LMO7 | LIM domain 7 | -0.125039 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.114798 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.110075 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.109448 |
| EZR | ezrin | -0.101525 |
| SP100 | SP100 nuclear antigen | -0.0996114 |
| ANXA2 | annexin A2 | -0.0951826 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0895677 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0876951 |
| RRBP1 | ribosome binding protein 1 | -0.0860232 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.077937 |
| NPSR1 | neuropeptide S receptor 1 | -0.0748827 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0735122 |
| XAF1 | XIAP associated factor 1 | -0.0707365 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0629274 |
| MX2 | MX dynamin-like GTPase 2 | -0.0624959 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0609567 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0608829 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0594654 |
| VCL | vinculin | -0.0591541 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0580599 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0567231 |
| PLSCR1 | phospholipid scramblase 1 | -0.0555305 |
| IRF1 | interferon regulatory factor 1 | -0.055124 |
| MUC20 | mucin 20, cell surface associated | -0.0545125 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0533302 |
| TJP1 | tight junction protein 1 | -0.0516147 |
| JUN | jun proto-oncogene | -0.0513357 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0496605 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0479711 |
| PTMA | prothymosin, alpha | -0.0466214 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0454439 |
| PLSCR2 | phospholipid scramblase 2 | -0.0453908 |
| RAB7A | RAB7A, member RAS oncogene family | -0.045202 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0448837 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0446994 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0446662 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0443172 |
| SPAG9 | sperm associated antigen 9 | -0.0436769 |
| ADIPOR2 | adiponectin receptor 2 | -0.0436521 |
| MX1 | MX dynamin-like GTPase 1 | -0.0430176 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0430067 |
| H1-0 | H1.0 linker histone | -0.0415425 |
| CANX | calnexin | -0.0413366 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0409395 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0408952 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0398722 |
| AHNAK | AHNAK nucleoprotein | -0.039736 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0387884 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0385252 |
| NDRG1 | N-myc downstream regulated 1 | -0.0382829 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0370092 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0368829 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0366937 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0360404 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0355563 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0353998 |
| POF1B | premature ovarian failure, 1B | -0.0352899 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0348931 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0341596 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0340578 |
| HDLBP | high density lipoprotein binding protein | -0.0338663 |
| FBXO39 | F-box protein 39 | -0.0335831 |
| EGR1 | early growth response 1 | -0.0334 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0331917 |
| CALR | calreticulin | -0.0331077 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0331015 |
| PRKCA | protein kinase C, alpha | -0.0325454 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.032323 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0322843 |
| TUFT1 | tuftelin 1 | -0.0322073 |
| ARF4 | ADP-ribosylation factor 4 | -0.0320543 |
| NABP1 | nucleic acid binding protein 1 | -0.031498 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0312395 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0312206 |
| LAMB3 | laminin, beta 3 | -0.0308474 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0302537 |
| TFRC | transferrin receptor | -0.030119 |
| HM13 | histocompatibility (minor) 13 | -0.0295447 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0294703 |
| MORF4L2 | mortality factor 4 like 2 | -0.0293453 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.029132 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0290511 |
| ANXA1 | annexin A1 | -0.0289674 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0287477 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0286447 |
| RBM39 | RNA binding motif protein 39 | -0.0285035 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0284286 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.028316 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0283089 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0282457 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0281674 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0281548 |