| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C3 | complement component 3 | 0.148399 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.074547 |
| IGF2 | insulin-like growth factor 2 | 0.0705187 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0656875 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0630354 |
| VCL | vinculin | 0.06188 |
| VEGFA | vascular endothelial growth factor A | 0.0616958 |
| FN1 | fibronectin 1 | 0.0550511 |
| TF | transferrin | 0.0529023 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0508558 |
| DSPP | dentin sialophosphoprotein | 0.0443043 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0438696 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0396349 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0393744 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0391218 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0387956 |
| SMAD3 | SMAD family member 3 | 0.037552 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0373277 |
| MRTFA | myocardin related transcription factor A | 0.0360282 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0352437 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.034919 |
| FAM107B | family with sequence similarity 107, member B | 0.0348884 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0342425 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0335476 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0334835 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.033202 |
| RPL3 | ribosomal protein L3 | 0.0330687 |
| AFDN | afadin, adherens junction formation factor | 0.0318157 |
| FOXO1 | forkhead box O1 | 0.0317508 |
| TNS1 | tensin 1 | 0.0304667 |
| GPC6 | glypican 6 | 0.0303499 |
| FILIP1L | filamin A interacting protein 1-like | 0.0302797 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0302561 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0302524 |
| BCL2L1 | BCL2-like 1 | 0.0301839 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0301136 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0299314 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0297142 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0294738 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0289113 |
| CPE | carboxypeptidase E | 0.0289024 |
| JAG1 | jagged 1 | 0.0287806 |
| FAT1 | FAT atypical cadherin 1 | 0.028654 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0278399 |
| ITGAV | integrin, alpha V | 0.0274077 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0268968 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267626 |
| CFB | complement factor B | 0.0264921 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0263942 |
| EHBP1 | EH domain binding protein 1 | 0.0255092 |
| KIF1B | kinesin family member 1B | 0.0253008 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0244963 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0243176 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0241174 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.023628 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0232321 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0228606 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0225697 |
| MYO1E | myosin IE | 0.0222694 |
| TUFT1 | tuftelin 1 | 0.0222275 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0215838 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0210384 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0208654 |
| SDC2 | syndecan 2 | 0.0208113 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0206736 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0204801 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0204321 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.020371 |
| TRIM26 | tripartite motif containing 26 | 0.0202262 |
| ADIPOR2 | adiponectin receptor 2 | 0.0198658 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0197834 |
| CCN2 | cellular communication network factor 2 | 0.0195587 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0195186 |
| FNDC3B | fibronectin type III domain containing 3B | 0.019317 |
| CCNY | cyclin Y | 0.0191408 |
| WDR43 | WD repeat domain 43 | 0.0190967 |
| SFTPA2 | surfactant protein A2 | 0.0190366 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0189757 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0185961 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0184979 |
| PCBP2 | poly(rC) binding protein 2 | 0.0184632 |
| PEG10 | paternally expressed 10 | 0.0179545 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0179377 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0179376 |
| TMEM181 | transmembrane protein 181 | 0.0179297 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0174864 |
| DIAPH1 | diaphanous-related formin 1 | 0.0174143 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0172491 |
| TCIM | transcriptional and immune response regulator | 0.0169742 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0165056 |
| FLNB | filamin B, beta | 0.0164906 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0163732 |
| TRIM24 | tripartite motif containing 24 | 0.0162944 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0162026 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0161533 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0160846 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0159606 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0154165 |
| PHF10 | PHD finger protein 10 | 0.0153804 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0148425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.241984 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.164968 |
| MT2A | metallothionein 2A | -0.160271 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146319 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.139696 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.117846 |
| FTL | ferritin, light polypeptide | -0.0977727 |
| RPS8 | ribosomal protein S8 | -0.0903178 |
| RPS6 | ribosomal protein S6 | -0.0860635 |
| RPLP1 | ribosomal protein, large, P1 | -0.0809133 |
| RPS24 | ribosomal protein S24 | -0.0791366 |
| APOA2 | apolipoprotein A-II | -0.0782334 |
| RPL35A | ribosomal protein L35a | -0.0743595 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0741777 |
| RPS19 | ribosomal protein S19 | -0.0685774 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0681008 |
| ENO1 | enolase 1, (alpha) | -0.0642447 |
| RPL12 | ribosomal protein L12 | -0.0637041 |
| TMSB10 | thymosin beta 10 | -0.0616514 |
| RPL34 | ribosomal protein L34 | -0.059825 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0559281 |
| APOB | apolipoprotein B | -0.0554748 |
| RPL37A | ribosomal protein L37a | -0.0538786 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0536798 |
| RPL11 | ribosomal protein L11 | -0.0514375 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.050007 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.049753 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0478419 |
| RPS29 | ribosomal protein S29 | -0.0465496 |
| RPLP2 | ribosomal protein, large, P2 | -0.0464231 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.045458 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0442635 |
| RPLP0 | ribosomal protein, large, P0 | -0.0427704 |
| RPS23 | ribosomal protein S23 | -0.0398022 |
| H1-0 | H1.0 linker histone | -0.0396826 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0391773 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0390386 |
| RPL23 | ribosomal protein L23 | -0.0387139 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0376128 |
| DTNA | dystrobrevin, alpha | -0.0375953 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0375766 |
| RPS21 | ribosomal protein S21 | -0.0373888 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0369997 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0368694 |
| RPL32 | ribosomal protein L32 | -0.0352127 |
| SBF2 | SET binding factor 2 | -0.0350796 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0345025 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0341907 |
| HMGA1 | high mobility group AT-hook 1 | -0.0341344 |
| GPC3 | glypican 3 | -0.034102 |
| RPS27A | ribosomal protein S27a | -0.0340726 |
| RPS25 | ribosomal protein S25 | -0.0339953 |
| RPL31 | ribosomal protein L31 | -0.0336047 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0334896 |
| ZNF292 | zinc finger protein 292 | -0.0331226 |
| RPS16 | ribosomal protein S16 | -0.032693 |
| FMNL2 | formin-like 2 | -0.0325889 |
| PTMA | prothymosin, alpha | -0.0317953 |
| RRBP1 | ribosome binding protein 1 | -0.0316948 |
| TMEM123 | transmembrane protein 123 | -0.0316123 |
| RPL19 | ribosomal protein L19 | -0.0312546 |
| RPS14 | ribosomal protein S14 | -0.0304358 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0303322 |
| WDR45B | WD repeat domain 45B | -0.0299352 |
| RPL27 | ribosomal protein L27 | -0.0298487 |
| RPL9 | ribosomal protein L9 | -0.0297718 |
| RPL36 | ribosomal protein L36 | -0.0293478 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0291668 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0291006 |
| S100A9 | S100 calcium binding protein A9 | -0.0288505 |
| RPL37 | ribosomal protein L37 | -0.0287464 |
| RPS11 | ribosomal protein S11 | -0.0286531 |
| BPTF | bromodomain PHD finger transcription factor | -0.0283677 |
| RPL26 | ribosomal protein L26 | -0.0283166 |
| TOP1 | topoisomerase (DNA) I | -0.0281612 |
| SQSTM1 | sequestosome 1 | -0.028159 |
| PTK2 | protein tyrosine kinase 2 | -0.0281319 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0280184 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0274966 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0271029 |
| S100A10 | S100 calcium binding protein A10 | -0.0264397 |
| RPS10 | ribosomal protein S10 | -0.0258221 |
| PERP | PERP, TP53 apoptosis effector | -0.0254957 |
| RPL8 | ribosomal protein L8 | -0.0253431 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0245635 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.024398 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0242079 |
| EXT1 | exostosin glycosyltransferase 1 | -0.024207 |
| RPS3 | ribosomal protein S3 | -0.024175 |
| RPS5 | ribosomal protein S5 | -0.0241645 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0237252 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0237107 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0236779 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0234542 |
| GNAS | GNAS complex locus | -0.0233599 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0233114 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0229289 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0229008 |
| PGK1 | phosphoglycerate kinase 1 | -0.0226784 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0226197 |
