| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.0892086 |
| VEGFA | vascular endothelial growth factor A | 0.0827144 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0731108 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0608557 |
| RPL3 | ribosomal protein L3 | 0.057055 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0531091 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0527152 |
| AREG | amphiregulin | 0.0515622 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0467057 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0453909 |
| KRT18 | keratin 18, type I | 0.0430658 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0410896 |
| RPLP0 | ribosomal protein, large, P0 | 0.040167 |
| CALR | calreticulin | 0.0392862 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0380837 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0369869 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0348385 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0347392 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0343206 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0317102 |
| MYO1E | myosin IE | 0.0316525 |
| LAMA4 | laminin, alpha 4 | 0.0316216 |
| ANXA1 | annexin A1 | 0.0296936 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0290639 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0284557 |
| RPL7 | ribosomal protein L7 | 0.0279203 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0278001 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0276805 |
| UBC | ubiquitin C | 0.0273372 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0271865 |
| BRD2 | bromodomain containing 2 | 0.0262498 |
| TMSB4X | thymosin beta 4, X-linked | 0.0256169 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0254722 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0246378 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0245185 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.022354 |
| TRIB1 | tribbles pseudokinase 1 | 0.0220479 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0220357 |
| EGR1 | early growth response 1 | 0.0219366 |
| PCBP2 | poly(rC) binding protein 2 | 0.021112 |
| S100P | S100 calcium binding protein P | 0.0209751 |
| RPS3 | ribosomal protein S3 | 0.020448 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0204319 |
| GDF15 | growth differentiation factor 15 | 0.0203168 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.02031 |
| RHOA | ras homolog family member A | 0.0202955 |
| KRT8 | keratin 8, type II | 0.0201702 |
| TPM3 | tropomyosin 3 | 0.019997 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0199353 |
| RND3 | Rho family GTPase 3 | 0.0196218 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0195764 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0195552 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0194179 |
| ARF4 | ADP-ribosylation factor 4 | 0.0190242 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0189041 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0187815 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0187194 |
| TUFT1 | tuftelin 1 | 0.0185702 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0185656 |
| CLDN4 | claudin 4 | 0.0180409 |
| ATF4 | activating transcription factor 4 | 0.0178975 |
| OCLN | occludin | 0.0176502 |
| ATF3 | activating transcription factor 3 | 0.0172609 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0171456 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0167132 |
| TJP1 | tight junction protein 1 | 0.0165936 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0165066 |
| EMP1 | epithelial membrane protein 1 | 0.0164155 |
| LIPH | lipase, member H | 0.0162782 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0162049 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.015726 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0155561 |
| JUN | jun proto-oncogene | 0.0155434 |
| RPL4 | ribosomal protein L4 | 0.0154706 |
| EFNB2 | ephrin-B2 | 0.015405 |
| RPS12 | ribosomal protein S12 | 0.0153275 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0152271 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0151151 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0149761 |
| RACK1 | receptor for activated C kinase 1 | 0.0145577 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0144645 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0143592 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0143543 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0142978 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.014252 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0141615 |
| EZR | ezrin | 0.0140222 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0139531 |
| DSPP | dentin sialophosphoprotein | 0.0138638 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.013749 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0137388 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0137111 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0136994 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.013699 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0135473 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0133678 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0132485 |
| RORA | RAR-related orphan receptor A | 0.0132005 |
| SFTPA2 | surfactant protein A2 | 0.0131807 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.013045 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229142 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.140105 |
| NPSR1 | neuropeptide S receptor 1 | -0.136012 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.113632 |
| PTMA | prothymosin, alpha | -0.10999 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.10728 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.10255 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.101167 |
| TMSB10 | thymosin beta 10 | -0.0969956 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0956727 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0837968 |
| RPL35A | ribosomal protein L35a | -0.0819179 |
| ACTG1 | actin gamma 1 | -0.0755434 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0730123 |
| NDRG1 | N-myc downstream regulated 1 | -0.0727309 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0710806 |
| RPS6 | ribosomal protein S6 | -0.0664578 |
| RNF43 | ring finger protein 43 | -0.0631343 |
| SMYD3 | SET and MYND domain containing 3 | -0.0623139 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0613324 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0605021 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0603649 |
| PRSS3 | protease, serine, 3 | -0.0601301 |
| ITGA6 | integrin, alpha 6 | -0.0598312 |
| FHIT | fragile histidine triad | -0.0580646 |
| TNS4 | tensin 4 | -0.0550529 |
| GPHN | gephyrin | -0.0532358 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0527618 |
| RPL34 | ribosomal protein L34 | -0.0527279 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0512232 |
| RPLP1 | ribosomal protein, large, P1 | -0.0497298 |
| ONECUT3 | one cut homeobox 3 | -0.0495367 |
| JMJD1C | jumonji domain containing 1C | -0.047285 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0468978 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0454853 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0454189 |
| S100A6 | S100 calcium binding protein A6 | -0.0453373 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0450413 |
| FERMT1 | fermitin family member 1 | -0.0444067 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0437622 |
| FAT1 | FAT atypical cadherin 1 | -0.0436528 |
| EHBP1 | EH domain binding protein 1 | -0.0432114 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0431272 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0429525 |
| CCND1 | cyclin D1 | -0.0429282 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0423885 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0417117 |
| NFIA | nuclear factor I/A | -0.0416753 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0411142 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0406073 |
| ANXA2 | annexin A2 | -0.0404317 |
| FLNB | filamin B, beta | -0.0404204 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0395912 |
| DEK | DEK proto-oncogene | -0.0395629 |
| SH3D19 | SH3 domain containing 19 | -0.0392297 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0389203 |
| RREB1 | ras responsive element binding protein 1 | -0.0388933 |
| ACTN4 | actinin, alpha 4 | -0.0388855 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.03843 |
| TMEM123 | transmembrane protein 123 | -0.0381962 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0373479 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0371795 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0369629 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0369467 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0369379 |
| AHNAK | AHNAK nucleoprotein | -0.0369277 |
| HMGA1 | high mobility group AT-hook 1 | -0.0366922 |
| FOXP1 | forkhead box P1 | -0.036395 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0361521 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0357096 |
| TPM4 | tropomyosin 4 | -0.0356675 |
| RPS24 | ribosomal protein S24 | -0.0356628 |
| RPS8 | ribosomal protein S8 | -0.0354357 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0352996 |
| S100A10 | S100 calcium binding protein A10 | -0.0351587 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0348619 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0345823 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0344029 |
| ZNF292 | zinc finger protein 292 | -0.0342092 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0341065 |
| PERP | PERP, TP53 apoptosis effector | -0.0332182 |
| CD2AP | CD2-associated protein | -0.0324923 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.032492 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0323385 |
| CD44 | CD44 molecule (Indian blood group) | -0.0321698 |
| PTEN | phosphatase and tensin homolog | -0.0319735 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0316816 |
| RPS21 | ribosomal protein S21 | -0.0316814 |
| IER3 | immediate early response 3 | -0.0315971 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0315356 |
| PGK1 | phosphoglycerate kinase 1 | -0.0311137 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0307682 |
| FTL | ferritin, light polypeptide | -0.0307095 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0306776 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0306501 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0306216 |
| AGR2 | anterior gradient 2 | -0.0304965 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0304166 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0304058 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0303461 |
