| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0825156 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.072484 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0502279 |
| DST | dystonin | 0.0484166 |
| TMSB4X | thymosin beta 4, X-linked | 0.0423405 |
| CANX | calnexin | 0.0389818 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0349448 |
| MYOF | myoferlin | 0.0294093 |
| CALR | calreticulin | 0.028394 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.028191 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0280536 |
| PTMA | prothymosin, alpha | 0.0272744 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0268923 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0263315 |
| EFNA5 | ephrin-A5 | 0.0263299 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0259282 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0257963 |
| EPHA4 | EPH receptor A4 | 0.0249173 |
| TNS3 | tensin 3 | 0.0244005 |
| APP | amyloid beta (A4) precursor protein | 0.0242149 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0240422 |
| AHNAK | AHNAK nucleoprotein | 0.0238048 |
| CD44 | CD44 molecule (Indian blood group) | 0.0237879 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.022676 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0224867 |
| OGA | O-GlcNAcase | 0.0219418 |
| SET | SET nuclear proto-oncogene | 0.0219084 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.020556 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0201467 |
| HDLBP | high density lipoprotein binding protein | 0.0200273 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0197539 |
| EHBP1 | EH domain binding protein 1 | 0.0186576 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0185102 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0181667 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0177932 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0175766 |
| SPAG9 | sperm associated antigen 9 | 0.0174993 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0171484 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0170955 |
| FNIP1 | folliculin interacting protein 1 | 0.0166407 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0161007 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0159179 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0154373 |
| HDAC9 | histone deacetylase 9 | 0.0149465 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0149169 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0147535 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0145606 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0145291 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0144562 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0142614 |
| LYST | lysosomal trafficking regulator | 0.0140644 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0137917 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0137772 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0137769 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0136675 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0135975 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0134891 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0133644 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.013332 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0132638 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0132325 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0130499 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0128565 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.012849 |
| PUM2 | pumilio RNA-binding family member 2 | 0.012754 |
| CADM2 | cell adhesion molecule 2 | 0.0126196 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0122009 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0120891 |
| SFTPA2 | surfactant protein A2 | 0.0120862 |
| RPL3 | ribosomal protein L3 | 0.0119953 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0118937 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0118015 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0117605 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0117084 |
| VEGFA | vascular endothelial growth factor A | 0.0116737 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0116342 |
| TPM3 | tropomyosin 3 | 0.0116056 |
| DOCK11 | dedicator of cytokinesis 11 | 0.011541 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0114797 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0113791 |
| AEBP2 | AE binding protein 2 | 0.0111385 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0110721 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0110492 |
| RPL4 | ribosomal protein L4 | 0.0110455 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0108469 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0106941 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0106108 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0104189 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0103627 |
| RPS27A | ribosomal protein S27a | 0.0103173 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0103073 |
| WDR43 | WD repeat domain 43 | 0.0102112 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0101908 |
| VCL | vinculin | 0.0101628 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0101006 |
| STAG2 | stromal antigen 2 | 0.0100018 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.00991595 |
| COPA | coatomer protein complex, subunit alpha | 0.00990672 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00989646 |
| LRRC49 | leucine rich repeat containing 49 | 0.0098298 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.348026 |
| MT2A | metallothionein 2A | -0.311749 |
| VIM | vimentin | -0.196623 |
| TMSB10 | thymosin beta 10 | -0.0839942 |
| MT1X | metallothionein 1X | -0.0746113 |
| MT1E | metallothionein 1E | -0.0715406 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0641429 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0641277 |
| TXNRD1 | thioredoxin reductase 1 | -0.0626537 |
| FTL | ferritin, light polypeptide | -0.0615473 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0577684 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0472517 |
| ACTG1 | actin gamma 1 | -0.044935 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0449023 |
| HMGA1 | high mobility group AT-hook 1 | -0.0446873 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0379136 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0376087 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0375724 |
| RPL35A | ribosomal protein L35a | -0.0372587 |
| SRGN | serglycin | -0.0372191 |
| RPS19 | ribosomal protein S19 | -0.0354292 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0333972 |
| ANGPTL4 | angiopoietin-like 4 | -0.0330151 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0323351 |
| AREG | amphiregulin | -0.0317807 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0309394 |
| FOSL1 | FOS-like antigen 1 | -0.0306768 |
| EMP1 | epithelial membrane protein 1 | -0.0299568 |
| RTN4 | reticulon 4 | -0.029546 |
| RPS8 | ribosomal protein S8 | -0.0290904 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0284418 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0271195 |
| S100A6 | S100 calcium binding protein A6 | -0.0267697 |
| PRDX1 | peroxiredoxin 1 | -0.0266785 |
| RPLP1 | ribosomal protein, large, P1 | -0.0262213 |
| S100A10 | S100 calcium binding protein A10 | -0.0261258 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0257895 |
| EGR1 | early growth response 1 | -0.0254937 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0248398 |
| RPS6 | ribosomal protein S6 | -0.0243166 |
| RPL5 | ribosomal protein L5 | -0.0240736 |
| RPLP2 | ribosomal protein, large, P2 | -0.0240617 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0232766 |
| YBX3 | Y box binding protein 3 | -0.0232462 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0228109 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0227951 |
| RPS23 | ribosomal protein S23 | -0.0225838 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0224013 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0222413 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0220947 |
| RPL23 | ribosomal protein L23 | -0.0219399 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0216118 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0214685 |
| S100A11 | S100 calcium binding protein A11 | -0.0211573 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0206973 |
| RBM25 | RNA binding motif protein 25 | -0.0206502 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0203862 |
| TMEM41B | transmembrane protein 41B | -0.0202696 |
| RAI1 | retinoic acid induced 1 | -0.0201258 |
| RPL32 | ribosomal protein L32 | -0.0200289 |
| CDCP1 | CUB domain containing protein 1 | -0.0199997 |
| RPL19 | ribosomal protein L19 | -0.0197258 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0192073 |
| BMERB1 | bMERB domain containing 1 | -0.0190886 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0186953 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0183543 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0182718 |
| VMP1 | vacuole membrane protein 1 | -0.0181649 |
| RPL36 | ribosomal protein L36 | -0.0179216 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0178652 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0176717 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0176703 |
| RPS15 | ribosomal protein S15 | -0.017389 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0169193 |
| RPL8 | ribosomal protein L8 | -0.0168326 |
| RPL35 | ribosomal protein L35 | -0.0168043 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0167412 |
| ERBIN | erbb2 interacting protein | -0.0166869 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0166082 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0165799 |
| PKM | pyruvate kinase, muscle | -0.0165711 |
| BPTF | bromodomain PHD finger transcription factor | -0.0164777 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0161059 |
| FERMT1 | fermitin family member 1 | -0.0160536 |
| EREG | epiregulin | -0.0160256 |
| PFN1 | profilin 1 | -0.0160067 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0158727 |
| TAPBP | TAP binding protein (tapasin) | -0.0152615 |
| RPS4X | ribosomal protein S4, X-linked | -0.0151063 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0149694 |
| MYADM | myeloid-associated differentiation marker | -0.0147266 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0145935 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0145372 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0143806 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0143341 |
| RPL28 | ribosomal protein L28 | -0.0143171 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0141215 |
| SVIL | supervillin | -0.0140789 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0140741 |
| RPS10 | ribosomal protein S10 | -0.0140147 |
