| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Aspirin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.0865552 |
| OSMR | oncostatin M receptor | 0.0607913 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0449892 |
| LAMC2 | laminin, gamma 2 | 0.037575 |
| SLTM | SAFB-like, transcription modulator | 0.034288 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0319306 |
| MKI67 | marker of proliferation Ki-67 | 0.0302892 |
| CES1 | carboxylesterase 1 | 0.0270459 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0270313 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0264679 |
| LAMA4 | laminin, alpha 4 | 0.0252589 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0240227 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0230175 |
| VCL | vinculin | 0.0197468 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0191985 |
| NABP1 | nucleic acid binding protein 1 | 0.0188316 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0186113 |
| PRELID2 | PRELI domain containing 2 | 0.0185571 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0182495 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0178809 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0176125 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0175488 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0171078 |
| KIAA1328 | KIAA1328 | 0.0168748 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0167584 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0165561 |
| GPATCH2L | G patch domain containing 2-like | 0.0162728 |
| RASA2 | RAS p21 protein activator 2 | 0.0160637 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0157743 |
| NGLY1 | N-glycanase 1 | 0.0156513 |
| KIAA1217 | KIAA1217 | 0.0156406 |
| BMP6 | bone morphogenetic protein 6 | 0.0154909 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0152328 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0152278 |
| KLC1 | kinesin light chain 1 | 0.0152119 |
| WDR26 | WD repeat domain 26 | 0.0151293 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0150429 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0148556 |
| RNF169 | ring finger protein 169 | 0.0148088 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0146704 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0146358 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0144788 |
| RUNX1 | runt-related transcription factor 1 | 0.0144661 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0144537 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0141109 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0138021 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0137733 |
| RTN4 | reticulon 4 | 0.0136452 |
| FAT1 | FAT atypical cadherin 1 | 0.013518 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0134297 |
| RLIM | ring finger protein, LIM domain interacting | 0.0132389 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0130899 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0129794 |
| PRKCE | protein kinase C, epsilon | 0.0129793 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0128102 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0127264 |
| ATP13A3 | ATPase type 13A3 | 0.0125139 |
| SETX | senataxin | 0.012471 |
| EXOC6B | exocyst complex component 6B | 0.0119313 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0117775 |
| KIAA0232 | KIAA0232 | 0.0116751 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0115903 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0115444 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0113449 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0113033 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0113032 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.011274 |
| RAB28 | RAB28, member RAS oncogene family | 0.0112097 |
| DTNA | dystrobrevin, alpha | 0.0111754 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0111042 |
| NF1 | neurofibromin 1 | 0.0110138 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0110092 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0109555 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0109078 |
| SLC35F5 | solute carrier family 35, member F5 | 0.010857 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0108002 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0107647 |
| ATP11A | ATPase, class VI, type 11A | 0.0106813 |
| CCNL1 | cyclin L1 | 0.0105952 |
| SEPTIN10 | septin 10 | 0.0104374 |
| MYO1B | myosin IB | 0.0104123 |
| CEP95 | centrosomal protein 95kDa | 0.0103761 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0102993 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0102942 |
| MYO5B | myosin VB | 0.0102416 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0102153 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0101764 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0101697 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0101512 |
| TMEM39A | transmembrane protein 39A | 0.0101509 |
| FRY | furry homolog (Drosophila) | 0.0100954 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.0100939 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0100846 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0100273 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0100131 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00998272 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00995619 |
| GOLGB1 | golgin B1 | 0.00992911 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.00984615 |
| PATJ | PATJ crumbs cell polarity complex component | 0.00978334 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.384658 |
| TMSB10 | thymosin beta 10 | -0.149288 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.116405 |
| NDRG1 | N-myc downstream regulated 1 | -0.0981515 |
| PTMA | prothymosin, alpha | -0.0975697 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0909555 |
| FTL | ferritin, light polypeptide | -0.0844607 |
| MT2A | metallothionein 2A | -0.0762666 |
| PKM | pyruvate kinase, muscle | -0.0757905 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0750426 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0737482 |
| FAM13A | family with sequence similarity 13, member A | -0.0694083 |
| S100A10 | S100 calcium binding protein A10 | -0.0664653 |
| RPS3 | ribosomal protein S3 | -0.0607014 |
| LDHA | lactate dehydrogenase A | -0.0564589 |
| SEC61G | Sec61 gamma subunit | -0.0557857 |
| ASPH | aspartate beta-hydroxylase | -0.0536288 |
| ENO1 | enolase 1, (alpha) | -0.0528735 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.051115 |
| RPLP1 | ribosomal protein, large, P1 | -0.0509737 |
| ANXA2 | annexin A2 | -0.0497291 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0487102 |
| RPL35A | ribosomal protein L35a | -0.0451768 |
| ACTG1 | actin gamma 1 | -0.0440025 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.042219 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0406713 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0398483 |
| B2M | beta-2-microglobulin | -0.0396338 |
| RPS25 | ribosomal protein S25 | -0.0395746 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0394653 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0393342 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0388054 |
| CST3 | cystatin C | -0.0386334 |
| RPS8 | ribosomal protein S8 | -0.0386188 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0384353 |
| EGR1 | early growth response 1 | -0.0377301 |
| RPLP0 | ribosomal protein, large, P0 | -0.0365229 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0364091 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0362324 |
| RPS6 | ribosomal protein S6 | -0.0357979 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0356746 |
| RPS12 | ribosomal protein S12 | -0.0349936 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0348176 |
| RPL37A | ribosomal protein L37a | -0.0347338 |
| CPE | carboxypeptidase E | -0.034678 |
| RPL31 | ribosomal protein L31 | -0.0334001 |
| RPS27A | ribosomal protein S27a | -0.0323428 |
| MYOF | myoferlin | -0.030944 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0304702 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.029804 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0295832 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0290015 |
| RPS24 | ribosomal protein S24 | -0.0289274 |
| KRT18 | keratin 18, type I | -0.028797 |
| S100P | S100 calcium binding protein P | -0.0284276 |
| RPL11 | ribosomal protein L11 | -0.0281227 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0279768 |
| TPD52 | tumor protein D52 | -0.0279343 |
| CAV2 | caveolin 2 | -0.027885 |
| KRT7 | keratin 7, type II | -0.0277782 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0274067 |
| RPL34 | ribosomal protein L34 | -0.0274065 |
| S100A6 | S100 calcium binding protein A6 | -0.0273681 |
| RPL12 | ribosomal protein L12 | -0.027186 |
| RPL8 | ribosomal protein L8 | -0.0271583 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0268059 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.026536 |
| STC1 | stanniocalcin 1 | -0.0259222 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0253417 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0252325 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0247514 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0244872 |
| IER3 | immediate early response 3 | -0.024451 |
| HMGA1 | high mobility group AT-hook 1 | -0.0244049 |
| GNAS | GNAS complex locus | -0.0241846 |
| RPS19 | ribosomal protein S19 | -0.0241185 |
| RPL19 | ribosomal protein L19 | -0.0240346 |
| PDE8A | phosphodiesterase 8A | -0.0238464 |
| WASF2 | WAS protein family, member 2 | -0.0237969 |
| RPL37 | ribosomal protein L37 | -0.0237202 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.023641 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0236245 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.023527 |
| CANX | calnexin | -0.0233904 |
| UBC | ubiquitin C | -0.0233577 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0229773 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0224669 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0224188 |
| S100A9 | S100 calcium binding protein A9 | -0.0221036 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0220415 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0220158 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0219397 |
| RACK1 | receptor for activated C kinase 1 | -0.021811 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0217553 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0216999 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0214777 |
| RPL7 | ribosomal protein L7 | -0.0214509 |
| RPL30 | ribosomal protein L30 | -0.0212339 |
| RPS29 | ribosomal protein S29 | -0.0211352 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0210555 |
