| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Aspirin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0589883 |
| SMAD3 | SMAD family member 3 | 0.0537004 |
| NAV2 | neuron navigator 2 | 0.0492312 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.048877 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0363554 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0348678 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.034669 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0342751 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0318645 |
| OGA | O-GlcNAcase | 0.031417 |
| OSMR | oncostatin M receptor | 0.0292933 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0284628 |
| ATP13A3 | ATPase type 13A3 | 0.0279067 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0272623 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.026995 |
| CD44 | CD44 molecule (Indian blood group) | 0.0261469 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0260632 |
| ADD3 | adducin 3 (gamma) | 0.0258366 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0249418 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0239719 |
| SIK3 | SIK family kinase 3 | 0.0238459 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.023703 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0233658 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0232402 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0230765 |
| EFNA5 | ephrin-A5 | 0.0229465 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0228736 |
| AHR | aryl hydrocarbon receptor | 0.0227057 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0225176 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0220159 |
| RBM39 | RNA binding motif protein 39 | 0.0216997 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0215421 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0208034 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0207707 |
| RUNX1 | runt-related transcription factor 1 | 0.0207575 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0199671 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.019747 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0197346 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0195043 |
| RUNX2 | runt-related transcription factor 2 | 0.019447 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0191326 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.019047 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0189585 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0189105 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0186097 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0185239 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0177596 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0177411 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0174404 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0171387 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.016724 |
| STK38L | serine/threonine kinase 38 like | 0.0165422 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0163661 |
| CAB39 | calcium binding protein 39 | 0.0159922 |
| PRELID2 | PRELI domain containing 2 | 0.0159071 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0156922 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0150833 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0145752 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0145714 |
| MED13L | mediator complex subunit 13-like | 0.0143044 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0142874 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0139783 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0137629 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0137223 |
| NBAS | neuroblastoma amplified sequence | 0.0134438 |
| RASA2 | RAS p21 protein activator 2 | 0.0132948 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0132725 |
| VWDE | von Willebrand factor D and EGF domains | 0.0132427 |
| DNMBP | dynamin binding protein | 0.0131559 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0131521 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0129356 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0129274 |
| IL1R1 | interleukin 1 receptor, type I | 0.0129057 |
| NEK7 | NIMA-related kinase 7 | 0.0128244 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0127462 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0126597 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0124357 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0124 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0123358 |
| SPAG9 | sperm associated antigen 9 | 0.0120672 |
| PHIP | pleckstrin homology domain interacting protein | 0.0120442 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0120144 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0119668 |
| SLTM | SAFB-like, transcription modulator | 0.0118392 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0117043 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0116998 |
| KLF6 | Kruppel-like factor 6 | 0.0116441 |
| PCNX1 | pecanex 1 | 0.011609 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0115723 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.0115691 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.011564 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0114794 |
| MYOF | myoferlin | 0.011466 |
| USP47 | ubiquitin specific peptidase 47 | 0.0114077 |
| CDK17 | cyclin-dependent kinase 17 | 0.0113199 |
| ABI1 | abl-interactor 1 | 0.0112417 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0111847 |
| FAM3C | family with sequence similarity 3, member C | 0.0111608 |
| OTUD7B | OTU deubiquitinase 7B | 0.0111191 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0110872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.180525 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.162491 |
| TMSB10 | thymosin beta 10 | -0.147729 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0965194 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0869574 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0805646 |
| FTL | ferritin, light polypeptide | -0.0742013 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0711104 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0698365 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.062467 |
| STC1 | stanniocalcin 1 | -0.0615181 |
| PTMA | prothymosin, alpha | -0.0597946 |
| FN1 | fibronectin 1 | -0.0562532 |
| B2M | beta-2-microglobulin | -0.049433 |
| NRG1 | neuregulin 1 | -0.0483648 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0481141 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0480934 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0479499 |
| S100A6 | S100 calcium binding protein A6 | -0.044687 |
| RPLP1 | ribosomal protein, large, P1 | -0.0444899 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0413969 |
| RPS19 | ribosomal protein S19 | -0.040782 |
| CDH13 | cadherin 13 | -0.0400468 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0398954 |
| RPS6 | ribosomal protein S6 | -0.0385361 |
| RPL35A | ribosomal protein L35a | -0.0383793 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0382558 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0376642 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0372574 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0359379 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0353809 |
| EGR1 | early growth response 1 | -0.0353159 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0352533 |
| RPS8 | ribosomal protein S8 | -0.0344633 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0344396 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0343525 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0337079 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0333313 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0329946 |
| CANX | calnexin | -0.0327552 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.032736 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.032119 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0321128 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0318588 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0314531 |
| ENO1 | enolase 1, (alpha) | -0.0308997 |
| RPL31 | ribosomal protein L31 | -0.0308057 |
| RPLP2 | ribosomal protein, large, P2 | -0.030799 |
| RPL36 | ribosomal protein L36 | -0.030702 |
| NDRG1 | N-myc downstream regulated 1 | -0.030545 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303393 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0301566 |
| RPS21 | ribosomal protein S21 | -0.029736 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0296789 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0293363 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0290935 |
| MT2A | metallothionein 2A | -0.0289512 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0288946 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0287126 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0285297 |
| PKM | pyruvate kinase, muscle | -0.0281681 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0277726 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0277572 |
| CUX1 | cut-like homeobox 1 | -0.0267162 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0262344 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0261604 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0260907 |
| CALU | calumenin | -0.0260892 |
| MEF2A | myocyte enhancer factor 2A | -0.0259609 |
| S100A10 | S100 calcium binding protein A10 | -0.0258079 |
| RPS13 | ribosomal protein S13 | -0.0258003 |
| RPS12 | ribosomal protein S12 | -0.0257337 |
| RPL32 | ribosomal protein L32 | -0.0257337 |
| IER3 | immediate early response 3 | -0.025355 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0253237 |
| RPL37A | ribosomal protein L37a | -0.025142 |
| HM13 | histocompatibility (minor) 13 | -0.0247273 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0244566 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0242149 |
| RPL34 | ribosomal protein L34 | -0.0241748 |
| LOX | lysyl oxidase | -0.024155 |
| RPS29 | ribosomal protein S29 | -0.0240711 |
| CLMP | CXADR-like membrane protein | -0.0239467 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0238568 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0237809 |
| RPL11 | ribosomal protein L11 | -0.023597 |
| TMEM165 | transmembrane protein 165 | -0.0235707 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0234064 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0233924 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0230852 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.023001 |
| ZNF609 | zinc finger protein 609 | -0.0228917 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0227832 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0227404 |
| RPS27 | ribosomal protein S27 | -0.0226096 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0226051 |
| DIAPH2 | diaphanous-related formin 2 | -0.0223408 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0218371 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0218319 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0218298 |