| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.184588 |
| VIM | vimentin | 0.14014 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.10008 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0977027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0972042 |
| POTEF | POTE ankyrin domain family, member F | 0.096762 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0920421 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.07913 |
| PYGL | phosphorylase, glycogen, liver | 0.0705719 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0681724 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0664591 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0663911 |
| LDHA | lactate dehydrogenase A | 0.0623007 |
| FLNB | filamin B, beta | 0.0511459 |
| MCL1 | myeloid cell leukemia 1 | 0.0503431 |
| CMIP | c-Maf inducing protein | 0.0492349 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0470813 |
| COPA | coatomer protein complex, subunit alpha | 0.0449404 |
| IGF2 | insulin-like growth factor 2 | 0.0419483 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0418775 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0415144 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0398099 |
| HDAC9 | histone deacetylase 9 | 0.0395991 |
| TPM4 | tropomyosin 4 | 0.0384303 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.037927 |
| UTRN | utrophin | 0.036431 |
| SVIL | supervillin | 0.0359328 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0346448 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0344516 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0337036 |
| RHOA | ras homolog family member A | 0.0331786 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0328674 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0328022 |
| TMSB10 | thymosin beta 10 | 0.0326071 |
| ACTG1 | actin gamma 1 | 0.0322202 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0320619 |
| AHNAK | AHNAK nucleoprotein | 0.0315207 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.030776 |
| RPLP0 | ribosomal protein, large, P0 | 0.0304531 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.030416 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0287577 |
| EGFR | epidermal growth factor receptor | 0.0287497 |
| EXT1 | exostosin glycosyltransferase 1 | 0.028719 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0285867 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0282919 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0280855 |
| EGR1 | early growth response 1 | 0.0278747 |
| S100A6 | S100 calcium binding protein A6 | 0.0276824 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0269813 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0269272 |
| ANGPTL4 | angiopoietin-like 4 | 0.025927 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0259028 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0255893 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0254599 |
| CUX1 | cut-like homeobox 1 | 0.0253924 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0251329 |
| RAD51B | RAD51 paralog B | 0.0248867 |
| PRR16 | proline rich 16 | 0.024504 |
| HMGA2 | high mobility group AT-hook 2 | 0.0242428 |
| ERBIN | erbb2 interacting protein | 0.0241044 |
| ENO1 | enolase 1, (alpha) | 0.0240728 |
| IL6 | interleukin 6 | 0.0238742 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0235528 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0233595 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0233186 |
| VCL | vinculin | 0.0232781 |
| FMNL2 | formin-like 2 | 0.0232693 |
| NF1 | neurofibromin 1 | 0.0228978 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0226598 |
| HLA-B | major histocompatibility complex, class I, B | 0.022346 |
| HLA-A | major histocompatibility complex, class I, A | 0.0218965 |
| FOXP1 | forkhead box P1 | 0.0214381 |
| CALR | calreticulin | 0.0213214 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0213026 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0212385 |
| ARF4 | ADP-ribosylation factor 4 | 0.021067 |
| KYNU | kynureninase | 0.0209583 |
| NEBL | nebulette | 0.0207854 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0207433 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0205777 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0205662 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0204672 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0203872 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0200523 |
| MYO1E | myosin IE | 0.0199954 |
| AK1 | adenylate kinase 1 | 0.0197807 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0197804 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0197404 |
| EHBP1 | EH domain binding protein 1 | 0.0194307 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194198 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0191938 |
| TPI1 | triosephosphate isomerase 1 | 0.0189238 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0189171 |
| THBS1 | thrombospondin 1 | 0.0188922 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0188719 |
| SFTPA2 | surfactant protein A2 | 0.018602 |
| NDRG1 | N-myc downstream regulated 1 | 0.0185955 |
| JUN | jun proto-oncogene | 0.0183355 |
| JUP | junction plakoglobin | 0.0179248 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0178649 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | -0.184898 |
| MT2A | metallothionein 2A | -0.133366 |
| GRAMD1B | GRAM domain containing 1B | -0.132653 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.129621 |
| RPS2 | ribosomal protein S2 | -0.10622 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.10252 |
| TXNRD1 | thioredoxin reductase 1 | -0.0995213 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.088231 |
| RTN4 | reticulon 4 | -0.0869444 |
| RPL19 | ribosomal protein L19 | -0.0828922 |
| RPS12 | ribosomal protein S12 | -0.0758568 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0752954 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0691412 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0678829 |
| YBX3 | Y box binding protein 3 | -0.0649135 |
| RBM39 | RNA binding motif protein 39 | -0.0635727 |
| FTL | ferritin, light polypeptide | -0.0635658 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0594974 |
| KIF5B | kinesin family member 5B | -0.0544818 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0534849 |
| WWOX | WW domain containing oxidoreductase | -0.0515653 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0493146 |
| PFDN2 | prefoldin subunit 2 | -0.0490589 |
| RPLP1 | ribosomal protein, large, P1 | -0.0486799 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0483227 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0473953 |
| WDR43 | WD repeat domain 43 | -0.0465558 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0462487 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0438118 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0437867 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0436144 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0418927 |
| ZNF292 | zinc finger protein 292 | -0.0416006 |
| USP3 | ubiquitin specific peptidase 3 | -0.0413871 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0392145 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0379151 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0375238 |
| QKI | QKI, KH domain containing, RNA binding | -0.0372879 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0368975 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0367309 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0366314 |
| DENND4A | DENN/MADD domain containing 4A | -0.0363209 |
| RPS21 | ribosomal protein S21 | -0.036276 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0362602 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.035913 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0357889 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0355466 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0354751 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0352696 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0349617 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0346649 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0336797 |
| GOLT1B | golgi transport 1B | -0.0333636 |
| RPS8 | ribosomal protein S8 | -0.0331633 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0329184 |
| CLTC | clathrin, heavy chain (Hc) | -0.0326479 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0325742 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.032242 |
| OLA1 | Obg-like ATPase 1 | -0.0316083 |
| RPS25 | ribosomal protein S25 | -0.0315655 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0314969 |
| RPS6 | ribosomal protein S6 | -0.0313411 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0308885 |
| IER3 | immediate early response 3 | -0.0308402 |
| RPL5 | ribosomal protein L5 | -0.0307492 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -0.0302848 |
| SPAG9 | sperm associated antigen 9 | -0.0302131 |
| PTMA | prothymosin, alpha | -0.0300969 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0299129 |
| MEMO1 | mediator of cell motility 1 | -0.0298804 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0293912 |
| RPL7 | ribosomal protein L7 | -0.0288842 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0286966 |
| RHEB | Ras homolog enriched in brain | -0.0286166 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0285366 |
| FAM168B | family with sequence similarity 168, member B | -0.0285276 |
| TPD52 | tumor protein D52 | -0.0284236 |
| WTAP | Wilms tumor 1 associated protein | -0.0281931 |
| NUP153 | nucleoporin 153kDa | -0.028171 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0281611 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0281485 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0281362 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0281136 |
| TNPO1 | transportin 1 | -0.0281094 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.028101 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0280942 |
| RBM33 | RNA binding motif protein 33 | -0.0279277 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.027916 |
| PAPOLA | poly(A) polymerase alpha | -0.0275286 |
| RPL36 | ribosomal protein L36 | -0.0275002 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0273861 |
| RPL26 | ribosomal protein L26 | -0.0272773 |
| RPL12 | ribosomal protein L12 | -0.0270712 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0270077 |
| NOP58 | NOP58 ribonucleoprotein | -0.0268514 |
| PNN | pinin, desmosome associated protein | -0.0267886 |
| POU2F1 | POU class 2 homeobox 1 | -0.0266726 |
| NCKAP1 | NCK-associated protein 1 | -0.026462 |
| SP3 | Sp3 transcription factor | -0.0263854 |
| JAK1 | Janus kinase 1 | -0.0261979 |
