| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0760978 |
| LAMA4 | laminin, alpha 4 | 0.0647265 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0621832 |
| KRT17 | keratin 17, type I | 0.0621546 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0583464 |
| FN1 | fibronectin 1 | 0.0561952 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0524132 |
| NDRG1 | N-myc downstream regulated 1 | 0.0505194 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0501701 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0478298 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0475827 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0463742 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0457155 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0456392 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0453624 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0447318 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0431973 |
| HELZ | helicase with zinc finger | 0.042732 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0420336 |
| FLNB | filamin B, beta | 0.0413147 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0410463 |
| GOLGA4 | golgin A4 | 0.0408421 |
| CADM1 | cell adhesion molecule 1 | 0.039642 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0395173 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0391721 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0386707 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0386484 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0385706 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0381346 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0380387 |
| RBM33 | RNA binding motif protein 33 | 0.0379423 |
| SMAD3 | SMAD family member 3 | 0.0373668 |
| GK | glycerol kinase | 0.0373654 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0373538 |
| EXOC4 | exocyst complex component 4 | 0.0373314 |
| RHOA | ras homolog family member A | 0.0372916 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0368289 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0367341 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0366456 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0363382 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0362499 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0362475 |
| DCP2 | decapping mRNA 2 | 0.0361252 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0353534 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0352918 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0347886 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0346833 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0346768 |
| BRD2 | bromodomain containing 2 | 0.0344914 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0344134 |
| ADM | adrenomedullin | 0.0343964 |
| COPA | coatomer protein complex, subunit alpha | 0.0343807 |
| TRIM2 | tripartite motif containing 2 | 0.0342693 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0338196 |
| CALR | calreticulin | 0.0335664 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0334727 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0333925 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0332363 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0330357 |
| FRMD6 | FERM domain containing 6 | 0.0328127 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.032636 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.032435 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0318514 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0318097 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.031629 |
| THBS1 | thrombospondin 1 | 0.0316046 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0315154 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.0314884 |
| COG5 | component of oligomeric golgi complex 5 | 0.0314323 |
| CLIC4 | chloride intracellular channel 4 | 0.0313593 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0309641 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0309327 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0308631 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0307418 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0307278 |
| RBM39 | RNA binding motif protein 39 | 0.0306984 |
| CA12 | carbonic anhydrase XII | 0.0304366 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0304018 |
| NGLY1 | N-glycanase 1 | 0.0300131 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0299488 |
| MPZL1 | myelin protein zero-like 1 | 0.0298787 |
| DLG5 | discs, large homolog 5 (Drosophila) | 0.0298555 |
| PDE10A | phosphodiesterase 10A | 0.0297316 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0295557 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.029431 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0292086 |
| PTEN | phosphatase and tensin homolog | 0.0289983 |
| KRT18 | keratin 18, type I | 0.0289972 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0287905 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0287809 |
| PRKD1 | protein kinase D1 | 0.0287516 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.02868 |
| VEGFA | vascular endothelial growth factor A | 0.028568 |
| TPR | translocated promoter region, nuclear basket protein | 0.028501 |
| RPS19 | ribosomal protein S19 | 0.028235 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.028174 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0280975 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0280929 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0275893 |
| RTN4 | reticulon 4 | 0.0273941 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.293198 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.159567 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.14641 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.140701 |
| ATOSA | atos homolog A | -0.137151 |
| TXNRD1 | thioredoxin reductase 1 | -0.119519 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.103139 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0932529 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0929178 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0895781 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0758456 |
| EGFR | epidermal growth factor receptor | -0.0714149 |
| SVIL | supervillin | -0.0706589 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0706231 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0674332 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0648468 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0646119 |
| ABHD17C | abhydrolase domain containing 17C | -0.0644595 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0643323 |
| PARD3 | par-3 family cell polarity regulator | -0.061884 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0615094 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0587058 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0577619 |
| RBM47 | RNA binding motif protein 47 | -0.0559802 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.052699 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.051885 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0514711 |
| AHNAK | AHNAK nucleoprotein | -0.0507008 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0484247 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0477312 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0474479 |
| TXNIP | thioredoxin interacting protein | -0.0473599 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0464272 |
| KYNU | kynureninase | -0.0457549 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0448084 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0447519 |
| ASPH | aspartate beta-hydroxylase | -0.0431622 |
| ACTG1 | actin gamma 1 | -0.042935 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0426448 |
| NEBL | nebulette | -0.042569 |
| SMYD3 | SET and MYND domain containing 3 | -0.0423116 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0420473 |
| LAMB3 | laminin, beta 3 | -0.0412833 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0412424 |
| MYO1E | myosin IE | -0.0409084 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0397659 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0390842 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0388852 |
| PKM | pyruvate kinase, muscle | -0.0387987 |
| TJP1 | tight junction protein 1 | -0.0387837 |
| FOXP1 | forkhead box P1 | -0.0382482 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0381595 |
| CCNI | cyclin I | -0.0369707 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0369536 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.03641 |
| HLA-B | major histocompatibility complex, class I, B | -0.0361583 |
| SQSTM1 | sequestosome 1 | -0.0360494 |
| MYO6 | myosin VI | -0.0353864 |
| SLMAP | sarcolemma associated protein | -0.0353741 |
| FOXO1 | forkhead box O1 | -0.0347843 |
| CUX1 | cut-like homeobox 1 | -0.034752 |
| NHSL1 | NHS-like 1 | -0.0342767 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0337252 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0331341 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0331025 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0330243 |
| RPL19 | ribosomal protein L19 | -0.0327301 |
| INHBA | inhibin, beta A | -0.032467 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0324431 |
| FOXO3 | forkhead box O3 | -0.0322945 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0321741 |
| TNPO1 | transportin 1 | -0.032094 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0320617 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319592 |
| TMSB10 | thymosin beta 10 | -0.0318491 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0317081 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0314641 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0314178 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0311651 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0311595 |
| MYO5C | myosin VC | -0.0311403 |
| HMGA2 | high mobility group AT-hook 2 | -0.030543 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0303775 |
| MUC16 | mucin 16, cell surface associated | -0.030255 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0302511 |
| BCL2L1 | BCL2-like 1 | -0.0302003 |
| MED13L | mediator complex subunit 13-like | -0.0298761 |
| RUNX1 | runt-related transcription factor 1 | -0.0298628 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0297637 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0297343 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0297215 |
| ANXA2 | annexin A2 | -0.0296448 |
| TUSC3 | tumor suppressor candidate 3 | -0.0291716 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0291156 |
| OGA | O-GlcNAcase | -0.0286882 |
| CMIP | c-Maf inducing protein | -0.0286015 |
| CLMP | CXADR-like membrane protein | -0.028466 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0284029 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0283612 |
| AK1 | adenylate kinase 1 | -0.0281669 |
