| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.187553 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0728378 |
| VEGFA | vascular endothelial growth factor A | 0.0604836 |
| CCNL1 | cyclin L1 | 0.0547161 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0491027 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.048463 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0449995 |
| MSN | moesin | 0.0398997 |
| MYO5B | myosin VB | 0.0388626 |
| FAM3C | family with sequence similarity 3, member C | 0.0387138 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0369118 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0368426 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0361731 |
| DUSP10 | dual specificity phosphatase 10 | 0.0358854 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0346762 |
| ZNF148 | zinc finger protein 148 | 0.0344074 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0336834 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0333073 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0330437 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324373 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0322612 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0315583 |
| UPP1 | uridine phosphorylase 1 | 0.0313943 |
| DTNA | dystrobrevin, alpha | 0.0312008 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0309995 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0299599 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.028657 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0285865 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0281108 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0280107 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0276851 |
| AFDN | afadin, adherens junction formation factor | 0.0276514 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0273771 |
| YAP1 | Yes-associated protein 1 | 0.0272183 |
| PTK2 | protein tyrosine kinase 2 | 0.0265895 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0259494 |
| RTN4 | reticulon 4 | 0.0259163 |
| VGLL3 | vestigial-like family member 3 | 0.0255663 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0248193 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0246172 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.024361 |
| NCKAP1 | NCK-associated protein 1 | 0.0240755 |
| RCOR1 | REST corepressor 1 | 0.0240664 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0237151 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0235724 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0229537 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0226516 |
| TNPO1 | transportin 1 | 0.0218064 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0216325 |
| MEF2A | myocyte enhancer factor 2A | 0.0216203 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0215725 |
| RBM33 | RNA binding motif protein 33 | 0.0214836 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0214828 |
| SMAD3 | SMAD family member 3 | 0.0214473 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0211508 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0209772 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0208879 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.020544 |
| XPO1 | exportin 1 | 0.0204925 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0203244 |
| ZNF654 | zinc finger protein 654 | 0.0199242 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0198868 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0198529 |
| ATP13A3 | ATPase type 13A3 | 0.0198269 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0197555 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0197139 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0196657 |
| SPAG9 | sperm associated antigen 9 | 0.0196416 |
| SNX9 | sorting nexin 9 | 0.019445 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0193636 |
| GOLGA4 | golgin A4 | 0.0193441 |
| BRD2 | bromodomain containing 2 | 0.0191105 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0190419 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0189675 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.018808 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.018725 |
| RYK | receptor-like tyrosine kinase | 0.0186656 |
| NUP98 | nucleoporin 98kDa | 0.0185092 |
| MYO10 | myosin X | 0.0183207 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0182714 |
| PLEC | plectin | 0.018195 |
| TUFT1 | tuftelin 1 | 0.0181262 |
| CORO1C | coronin, actin binding protein, 1C | 0.0181086 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0180847 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0179679 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0179165 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0178891 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0177749 |
| NUP58 | nucleoporin 58 | 0.0177448 |
| TXNRD1 | thioredoxin reductase 1 | 0.017597 |
| ZNF292 | zinc finger protein 292 | 0.0175632 |
| YY1AP1 | YY1 associated protein 1 | 0.0175608 |
| STK24 | serine/threonine kinase 24 | 0.0173305 |
| YTHDC1 | YTH domain containing 1 | 0.0173192 |
| RASA2 | RAS p21 protein activator 2 | 0.0172555 |
| CUL3 | cullin 3 | 0.0171418 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0169665 |
| TAPBP | TAP binding protein (tapasin) | 0.0168939 |
| JUP | junction plakoglobin | 0.016726 |
| HPCAL1 | hippocalcin-like 1 | 0.0167063 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.168989 |
| FTL | ferritin, light polypeptide | -0.153624 |
| TMSB10 | thymosin beta 10 | -0.152038 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.105762 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0940257 |
| S100A6 | S100 calcium binding protein A6 | -0.0899245 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0843528 |
| TMSB4X | thymosin beta 4, X-linked | -0.0740612 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0730736 |
| CCND1 | cyclin D1 | -0.072766 |
| LMO7 | LIM domain 7 | -0.072321 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0710212 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.06794 |
| ASPH | aspartate beta-hydroxylase | -0.0665174 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0637361 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0613716 |
| RPLP1 | ribosomal protein, large, P1 | -0.0605084 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0585698 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0547656 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0534094 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0527871 |
| CSTB | cystatin B (stefin B) | -0.0520329 |
| PLAU | plasminogen activator, urokinase | -0.0516505 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0510104 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0509298 |
| LMNA | lamin A/C | -0.0496748 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0495964 |
| S100A10 | S100 calcium binding protein A10 | -0.0494493 |
| RPS3 | ribosomal protein S3 | -0.0490594 |
| KRT7 | keratin 7, type II | -0.0488657 |
| CALR | calreticulin | -0.0482559 |
| CANX | calnexin | -0.0482176 |
| TPI1 | triosephosphate isomerase 1 | -0.0475427 |
| RPL34 | ribosomal protein L34 | -0.0471113 |
| RPL12 | ribosomal protein L12 | -0.0465773 |
| EPCAM | epithelial cell adhesion molecule | -0.0462635 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0448553 |
| ENO1 | enolase 1, (alpha) | -0.0434494 |
| CD2AP | CD2-associated protein | -0.0429465 |
| RRBP1 | ribosome binding protein 1 | -0.0428153 |
| RPS19 | ribosomal protein S19 | -0.0427302 |
| SQSTM1 | sequestosome 1 | -0.0425039 |
| TPM4 | tropomyosin 4 | -0.0421238 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.041917 |
| GNAS | GNAS complex locus | -0.0415483 |
| LAMB3 | laminin, beta 3 | -0.0412023 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0408316 |
| RPS8 | ribosomal protein S8 | -0.040543 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0402542 |
| RPS27 | ribosomal protein S27 | -0.0399937 |
| HDLBP | high density lipoprotein binding protein | -0.0394771 |
| TOP1 | topoisomerase (DNA) I | -0.0393047 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.039304 |
| EFNA5 | ephrin-A5 | -0.0391391 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.039117 |
| KRT19 | keratin 19, type I | -0.0391024 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0390105 |
| PGK1 | phosphoglycerate kinase 1 | -0.0389149 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0375524 |
| G0S2 | G0/G1 switch 2 | -0.0369254 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0366445 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0364617 |
| RPLP2 | ribosomal protein, large, P2 | -0.0363613 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0362225 |
| TMEM263 | transmembrane protein 263 | -0.0359256 |
| CD63 | CD63 molecule | -0.035527 |
| CAVIN1 | caveolae associated protein 1 | -0.035522 |
| MT2A | metallothionein 2A | -0.0355008 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0352514 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0348839 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.034744 |
| HLA-A | major histocompatibility complex, class I, A | -0.0341773 |
| ARF1 | ADP-ribosylation factor 1 | -0.0338772 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0338332 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0337333 |
| RPL35A | ribosomal protein L35a | -0.0334409 |
| H1-0 | H1.0 linker histone | -0.0332055 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0328718 |
| B2M | beta-2-microglobulin | -0.0327755 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0320029 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0318566 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0315784 |
| S100A11 | S100 calcium binding protein A11 | -0.031508 |
| RACK1 | receptor for activated C kinase 1 | -0.0314877 |
| RPL32 | ribosomal protein L32 | -0.0314372 |
| RPL19 | ribosomal protein L19 | -0.0313125 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0312223 |
| RPL8 | ribosomal protein L8 | -0.0311806 |
| HMGB1 | high mobility group box 1 | -0.0310409 |
| FAM13A | family with sequence similarity 13, member A | -0.0310169 |
| RPS14 | ribosomal protein S14 | -0.0309479 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0305389 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0299577 |
| RPS29 | ribosomal protein S29 | -0.0297843 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0287976 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0285497 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0284345 |
| MYOF | myoferlin | -0.0284117 |
| KRT18 | keratin 18, type I | -0.028171 |
| RNF213 | ring finger protein 213 | -0.0279464 |
