| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aspirin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aspirin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0612557 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0572188 |
| YAP1 | Yes-associated protein 1 | 0.054488 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0526506 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0520982 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0482758 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0466084 |
| GOLGA4 | golgin A4 | 0.0444568 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0439792 |
| SMYD3 | SET and MYND domain containing 3 | 0.0425729 |
| OSMR | oncostatin M receptor | 0.0425219 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0419552 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0411587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0357894 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0342093 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0336005 |
| TPX2 | TPX2, microtubule-associated | 0.0326082 |
| YTHDC1 | YTH domain containing 1 | 0.0318164 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031479 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0310362 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0309763 |
| COG5 | component of oligomeric golgi complex 5 | 0.0306704 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0300045 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0288336 |
| KIF5B | kinesin family member 5B | 0.0286753 |
| COG6 | component of oligomeric golgi complex 6 | 0.028216 |
| CDC42SE2 | CDC42 small effector 2 | 0.0280533 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0279363 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0275152 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0273957 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0270857 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0267021 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0266473 |
| SET | SET nuclear proto-oncogene | 0.026589 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0261864 |
| ATP13A3 | ATPase type 13A3 | 0.0260839 |
| PCNX4 | pecanex 4 | 0.0254001 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0253476 |
| HJURP | Holliday junction recognition protein | 0.0249521 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0248238 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0247256 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0244694 |
| COPA | coatomer protein complex, subunit alpha | 0.0243298 |
| CLTC | clathrin, heavy chain (Hc) | 0.0242645 |
| SEPTIN2 | septin 2 | 0.0242506 |
| GOLM2 | golgi membrane protein 2 | 0.0240579 |
| RPS16 | ribosomal protein S16 | 0.0240045 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0238603 |
| NUP58 | nucleoporin 58 | 0.0237928 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0237375 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0237332 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0235539 |
| GOLGA2 | golgin A2 | 0.0233064 |
| SGO2 | shugoshin 2 | 0.0231836 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0230957 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0227358 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0226777 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0226106 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0225406 |
| RANBP2 | RAN binding protein 2 | 0.0223825 |
| KLHL24 | kelch-like family member 24 | 0.0223393 |
| CUL3 | cullin 3 | 0.0223163 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0223084 |
| CEP250 | centrosomal protein 250kDa | 0.0222887 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0222527 |
| TXNIP | thioredoxin interacting protein | 0.0221544 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0221182 |
| RNF216 | ring finger protein 216 | 0.0220901 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0220063 |
| SEC24A | SEC24 family member A | 0.0219247 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0218662 |
| ZNF292 | zinc finger protein 292 | 0.021677 |
| CEP295 | centrosomal protein 295kDa | 0.021566 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0215122 |
| CENPF | centromere protein F, 350/400kDa | 0.0214148 |
| IPO5 | importin 5 | 0.0213517 |
| GOLT1B | golgi transport 1B | 0.0209923 |
| TXNRD1 | thioredoxin reductase 1 | 0.0208792 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.0208004 |
| CUL5 | cullin 5 | 0.0207015 |
| TMEM245 | transmembrane protein 245 | 0.0207 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0206883 |
| WDR43 | WD repeat domain 43 | 0.0206792 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0206196 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0206007 |
| DIAPH3 | diaphanous-related formin 3 | 0.020559 |
| FAM117B | family with sequence similarity 117, member B | 0.0205108 |
| KIAA1958 | KIAA1958 | 0.0204918 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0202799 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.020232 |
| RBM6 | RNA binding motif protein 6 | 0.0202006 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0201154 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0200917 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0200326 |
| PER1 | period circadian clock 1 | 0.0198974 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0196592 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.019658 |
| TPM3 | tropomyosin 3 | 0.0195465 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.0194899 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0194236 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153614 |
| VIM | vimentin | -0.136939 |
| TMSB10 | thymosin beta 10 | -0.110291 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0970662 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0937943 |
| PTMA | prothymosin, alpha | -0.0889184 |
| LDHA | lactate dehydrogenase A | -0.088511 |
| ANGPTL4 | angiopoietin-like 4 | -0.0865989 |
| HMGA2 | high mobility group AT-hook 2 | -0.0796182 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0786096 |
| CD44 | CD44 molecule (Indian blood group) | -0.0740561 |
| PRSS23 | protease, serine, 23 | -0.0680759 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0671385 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.06689 |
| DST | dystonin | -0.0661071 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0640049 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0593732 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0583347 |
| FMNL2 | formin-like 2 | -0.0581439 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0568602 |
| POTEF | POTE ankyrin domain family, member F | -0.0565424 |
| MAP1B | microtubule-associated protein 1B | -0.0551253 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0550596 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0547516 |
| ANXA2 | annexin A2 | -0.0547323 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0543376 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.053354 |
| PRKCA | protein kinase C, alpha | -0.0530987 |
| IGF2 | insulin-like growth factor 2 | -0.0527018 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0526401 |
| RIGI | RNA sensor RIG-I | -0.0523329 |
| SVIL | supervillin | -0.0512196 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0504606 |
| FLNB | filamin B, beta | -0.0496076 |
| PTK2 | protein tyrosine kinase 2 | -0.0495631 |
| RAD51B | RAD51 paralog B | -0.0493805 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0485212 |
| AHNAK | AHNAK nucleoprotein | -0.04784 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0473398 |
| S100A10 | S100 calcium binding protein A10 | -0.0473318 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0465083 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0461496 |
| RAI14 | retinoic acid induced 14 | -0.0461491 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0460621 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0459248 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0455939 |
| RPLP1 | ribosomal protein, large, P1 | -0.0448109 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0447499 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0437738 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0436158 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0433603 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0428938 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0428191 |
| SPAG9 | sperm associated antigen 9 | -0.0423364 |
| CCND1 | cyclin D1 | -0.0421942 |
| B2M | beta-2-microglobulin | -0.04207 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0418031 |
| NAV2 | neuron navigator 2 | -0.0414819 |
| SQSTM1 | sequestosome 1 | -0.0402973 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0396169 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0394214 |
| GNAS | GNAS complex locus | -0.0393623 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0387351 |
| MT2A | metallothionein 2A | -0.0387243 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0385898 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0380772 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0378292 |
| RPL26 | ribosomal protein L26 | -0.0374867 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0371385 |
| SDC4 | syndecan 4 | -0.0368314 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0366638 |
| EXOC4 | exocyst complex component 4 | -0.0362877 |
| PRR16 | proline rich 16 | -0.0357742 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0354724 |
| INTS6 | integrator complex subunit 6 | -0.0350788 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0350725 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0350593 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0348359 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0347737 |
| DPYD | dihydropyrimidine dehydrogenase | -0.034577 |
| PODXL | podocalyxin-like | -0.0341298 |
| ACTN1 | actinin, alpha 1 | -0.0338689 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.033846 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0338442 |
| IER3 | immediate early response 3 | -0.0338117 |
| HLA-B | major histocompatibility complex, class I, B | -0.033607 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0332581 |
| PCED1B | PC-esterase domain containing 1B | -0.0326137 |
| RPL35A | ribosomal protein L35a | -0.0322435 |
| PKM | pyruvate kinase, muscle | -0.0322378 |
| FUS | FUS RNA binding protein | -0.0321123 |
| S100A9 | S100 calcium binding protein A9 | -0.0318496 |
| RPS3 | ribosomal protein S3 | -0.0315362 |
| RPS8 | ribosomal protein S8 | -0.0315092 |
| PFN1 | profilin 1 | -0.0314533 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0314217 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0308405 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0306853 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0303826 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0301645 |
