Asthma Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety. (Human Disease Ontology, DOID_2841)
External Link
Similar Terms
Downloads & Tools


29 genes associated with the Asthma phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
NOTCH4 notch 4 1.13226
GSDMB gasdermin B 0.896275
IL1RL1 interleukin 1 receptor-like 1 0.849268
PBX2 pre-B-cell leukemia homeobox 2 0.849268
C6ORF10 chromosome 6 open reading frame 10 0.841354
IKZF4 IKAROS family zinc finger 4 (Eos) 0.750033
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.750033
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.729497
HCG23 HLA complex group 23 (non-protein coding) 0.673878
IL18R1 interleukin 18 receptor 1 0.483518
SMAD3 SMAD family member 3 0.472799
PYHIN1 pyrin and HIN domain family, member 1 0.472799
GSDMA gasdermin A 0.463473
LOC101928947 uncharacterized LOC101928947 0.434785
IL2RB interleukin 2 receptor, beta 0.434785
IL6R interleukin 6 receptor 0.405958
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.405958
PDE4D phosphodiesterase 4D, cAMP-specific 0.389385
GAB1 GRB2-associated binding protein 1 0.356403
IL13 interleukin 13 0.342586
RORA RAR-related orphan receptor A 0.342586
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.314454
RAD50 RAD50 homolog (S. cerevisiae) 0.295129
PRKG1 protein kinase, cGMP-dependent, type I 0.266721
LOC101928940 uncharacterized LOC101928940 0.255654
C5ORF56 chromosome 5 open reading frame 56 0.165905
ACO1 aconitase 1, soluble 0.104568
ZNF665 zinc finger protein 665 0.104568
MAVS mitochondrial antiviral signaling protein 0.048624