Asthma Gene Set
Dataset
GWAS Catalog SNP-Phenotype Associations
Category
disease or phenotype associations
Type
phenotype
Description
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety. (Human Disease Ontology , DOID_2841 )
External Link
https://www.ebi.ac.uk/gwas/search?query=Asthma
Similar Terms
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Genes
29 genes associated with the Asthma phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.
Symbol
Name
Standardized Value
NOTCH4
notch 4
1.13226
GSDMB
gasdermin B
0.896275
IL1RL1
interleukin 1 receptor-like 1
0.849268
PBX2
pre-B-cell leukemia homeobox 2
0.849268
C6ORF10
chromosome 6 open reading frame 10
0.841354
IKZF4
IKAROS family zinc finger 4 (Eos)
0.750033
CRB1
crumbs family member 1, photoreceptor morphogenesis associated
0.750033
SLC30A8
solute carrier family 30 (zinc transporter), member 8
0.729497
HCG23
HLA complex group 23 (non-protein coding)
0.673878
IL18R1
interleukin 18 receptor 1
0.483518
SMAD3
SMAD family member 3
0.472799
PYHIN1
pyrin and HIN domain family, member 1
0.472799
GSDMA
gasdermin A
0.463473
LOC101928947
uncharacterized LOC101928947
0.434785
IL2RB
interleukin 2 receptor, beta
0.434785
IL6R
interleukin 6 receptor
0.405958
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
0.405958
PDE4D
phosphodiesterase 4D, cAMP-specific
0.389385
GAB1
GRB2-associated binding protein 1
0.356403
IL13
interleukin 13
0.342586
RORA
RAR-related orphan receptor A
0.342586
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
0.314454
RAD50
RAD50 homolog (S. cerevisiae)
0.295129
PRKG1
protein kinase, cGMP-dependent, type I
0.266721
LOC101928940
uncharacterized LOC101928940
0.255654
C5ORF56
chromosome 5 open reading frame 56
0.165905
ACO1
aconitase 1, soluble
0.104568
ZNF665
zinc finger protein 665
0.104568
MAVS
mitochondrial antiviral signaling protein
0.048624
