Astigmatism Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed). (Experimental Factor Ontology, EFO_0004222)
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Genes

5 genes associated with the trait Astigmatism in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.774665
PRRX2 paired related homeobox 2 0.527821
RPL22P13 ribosomal protein L22 pseudogene 13 0.443956
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 0.356676
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.356676