| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.131027 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.113767 |
| COL3A1 | collagen, type III, alpha 1 | 0.107467 |
| CALR | calreticulin | 0.105354 |
| CSTB | cystatin B (stefin B) | 0.0946846 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0938633 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0937623 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0879812 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0839346 |
| APP | amyloid beta (A4) precursor protein | 0.0792777 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0706475 |
| COL5A2 | collagen, type V, alpha 2 | 0.0705469 |
| SFTPA2 | surfactant protein A2 | 0.0700532 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0693413 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.066311 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0635089 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.062911 |
| THBS2 | thrombospondin 2 | 0.0619285 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0617175 |
| CANX | calnexin | 0.0613535 |
| TMSB4X | thymosin beta 4, X-linked | 0.0599943 |
| OGA | O-GlcNAcase | 0.0594212 |
| AUTS2 | autism susceptibility candidate 2 | 0.0591607 |
| DST | dystonin | 0.0589706 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0589056 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0584507 |
| TPM3 | tropomyosin 3 | 0.0576373 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.052443 |
| CTSB | cathepsin B | 0.0517404 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0502395 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0502101 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0496693 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0476937 |
| MYOF | myoferlin | 0.0463503 |
| FLNB | filamin B, beta | 0.0456548 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0455173 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0434369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0432462 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0422073 |
| CD44 | CD44 molecule (Indian blood group) | 0.0414659 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0406096 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0405391 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0402459 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0397586 |
| SCRN1 | secernin 1 | 0.0397403 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0393678 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0389699 |
| CD109 | CD109 molecule | 0.0388254 |
| SBF2 | SET binding factor 2 | 0.0387982 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0385926 |
| LDHA | lactate dehydrogenase A | 0.0382643 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0376319 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0376254 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0374761 |
| GOLGA4 | golgin A4 | 0.0369533 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0362231 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0361369 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0361217 |
| COL4A2 | collagen, type IV, alpha 2 | 0.035263 |
| LOXL2 | lysyl oxidase-like 2 | 0.03462 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0345624 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0343321 |
| MEF2A | myocyte enhancer factor 2A | 0.0339693 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0338131 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0333427 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0331475 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0324284 |
| RAB10 | RAB10, member RAS oncogene family | 0.032169 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321136 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0317839 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0313106 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0313073 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0312259 |
| CLTC | clathrin, heavy chain (Hc) | 0.030794 |
| ATP13A3 | ATPase type 13A3 | 0.0304277 |
| LOX | lysyl oxidase | 0.0301628 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0296494 |
| FSTL1 | follistatin-like 1 | 0.0296123 |
| SET | SET nuclear proto-oncogene | 0.029368 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0291731 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0291322 |
| RND3 | Rho family GTPase 3 | 0.0288685 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0287636 |
| UBQLN1 | ubiquilin 1 | 0.0285237 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0284078 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0283246 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.028226 |
| DENND5A | DENN/MADD domain containing 5A | 0.0281998 |
| PLEC | plectin | 0.0281951 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0276307 |
| FBN1 | fibrillin 1 | 0.0275388 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0274601 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0274367 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0274358 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0273125 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0271879 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0271153 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0270548 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0267255 |
| NPC1 | Niemann-Pick disease, type C1 | 0.026572 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.245251 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.235982 |
| TMSB10 | thymosin beta 10 | -0.122654 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.117285 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0940744 |
| VIM | vimentin | -0.0809677 |
| MX2 | MX dynamin-like GTPase 2 | -0.0741901 |
| MYADM | myeloid-associated differentiation marker | -0.0707842 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0574139 |
| MEIS2 | Meis homeobox 2 | -0.0569453 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0521667 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0513671 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0490637 |
| SUCNR1 | succinate receptor 1 | -0.0438306 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0430032 |
| HLA-B | major histocompatibility complex, class I, B | -0.0429862 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0415745 |
| RIGI | RNA sensor RIG-I | -0.0410185 |
| PLAT | plasminogen activator, tissue | -0.0405606 |
| POTEF | POTE ankyrin domain family, member F | -0.0402115 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0400016 |
| TAPBP | TAP binding protein (tapasin) | -0.0387616 |
| COL1A2 | collagen, type I, alpha 2 | -0.0381105 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0380267 |
| MAP1B | microtubule-associated protein 1B | -0.0373414 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0366488 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0364741 |
| FOSL1 | FOS-like antigen 1 | -0.0359265 |
| CUX1 | cut-like homeobox 1 | -0.0352655 |
| HLA-C | major histocompatibility complex, class I, C | -0.0339091 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0328674 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.032166 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0318841 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.031882 |
| EGR1 | early growth response 1 | -0.0315395 |
| VEGFA | vascular endothelial growth factor A | -0.0310458 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0307256 |
| CCND1 | cyclin D1 | -0.030112 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0300512 |
| ACTG1 | actin gamma 1 | -0.0278274 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0273258 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0270147 |
| HSPB1 | heat shock 27kDa protein 1 | -0.026875 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0266173 |
| COPA | coatomer protein complex, subunit alpha | -0.0263487 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0258312 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0256468 |
| LMNA | lamin A/C | -0.025456 |
| HLA-A | major histocompatibility complex, class I, A | -0.0251453 |
| CDH13 | cadherin 13 | -0.0248891 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.024773 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0246953 |
| CD99 | CD99 molecule | -0.0245315 |
| RPL28 | ribosomal protein L28 | -0.0238882 |
| RTN4 | reticulon 4 | -0.0238291 |
| FN1 | fibronectin 1 | -0.0237557 |
| TAGLN2 | transgelin 2 | -0.0236509 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0235155 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0230507 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0229329 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0229278 |
| PXDN | peroxidasin | -0.0227466 |
| MT2A | metallothionein 2A | -0.0224396 |
| SP100 | SP100 nuclear antigen | -0.0220654 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0218713 |
| UBC | ubiquitin C | -0.0218571 |
| LAMA5 | laminin, alpha 5 | -0.02152 |
| SMIM44 | small integral membrane protein 44 | -0.0213396 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0212313 |
| NAV1 | neuron navigator 1 | -0.0211622 |
| PLSCR1 | phospholipid scramblase 1 | -0.0208396 |
| RNF213 | ring finger protein 213 | -0.0207098 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0205955 |
| FADS2 | fatty acid desaturase 2 | -0.020459 |
| PFN1 | profilin 1 | -0.0202496 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0193736 |
| JUN | jun proto-oncogene | -0.0190487 |
| MTDH | metadherin | -0.0188429 |
| JAZF1 | JAZF zinc finger 1 | -0.0187998 |
| PKM | pyruvate kinase, muscle | -0.0187259 |
| RPS15 | ribosomal protein S15 | -0.0187094 |
| ACLY | ATP citrate lyase | -0.01868 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0186664 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0179845 |
| RPS6 | ribosomal protein S6 | -0.0179509 |
| SYT1 | synaptotagmin I | -0.0178893 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0176304 |
| CTSD | cathepsin D | -0.0175554 |
| TPI1 | triosephosphate isomerase 1 | -0.0175261 |
| PML | promyelocytic leukemia | -0.017456 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0173534 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0172685 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0172301 |
| BPTF | bromodomain PHD finger transcription factor | -0.0170754 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0169944 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0169461 |
| RPL9 | ribosomal protein L9 | -0.0168894 |
| IL7R | interleukin 7 receptor | -0.0167575 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0167356 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0166332 |
