| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.193007 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.112677 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109057 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0801057 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0721628 |
| LPIN1 | lipin 1 | 0.0661207 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0589047 |
| CANX | calnexin | 0.0531004 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0498627 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0494234 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0482314 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.047664 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0474088 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0470954 |
| MCL1 | myeloid cell leukemia 1 | 0.0433825 |
| HMGB2 | high mobility group box 2 | 0.0412247 |
| VCL | vinculin | 0.0408577 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0372296 |
| TOB1 | transducer of ERBB2, 1 | 0.0366539 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0366085 |
| ENAH | enabled homolog (Drosophila) | 0.0360225 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0355547 |
| GPC5 | glypican 5 | 0.0352887 |
| SFTPA2 | surfactant protein A2 | 0.0352487 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0343358 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0338286 |
| ENO1 | enolase 1, (alpha) | 0.0336645 |
| TPM3 | tropomyosin 3 | 0.0331436 |
| IGF2 | insulin-like growth factor 2 | 0.0330733 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0328745 |
| RBM33 | RNA binding motif protein 33 | 0.0320717 |
| CCNY | cyclin Y | 0.0318944 |
| LDHA | lactate dehydrogenase A | 0.0318551 |
| PCM1 | pericentriolar material 1 | 0.031717 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0317033 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.031586 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314732 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0314212 |
| SNX14 | sorting nexin 14 | 0.0314065 |
| THBS1 | thrombospondin 1 | 0.0303425 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0301367 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0299732 |
| PHF3 | PHD finger protein 3 | 0.0295003 |
| AFDN | afadin, adherens junction formation factor | 0.0291584 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0291194 |
| DST | dystonin | 0.0290289 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0288099 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0288037 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0286375 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0283286 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.028109 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0274171 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0272147 |
| SET | SET nuclear proto-oncogene | 0.0272142 |
| GOLGA4 | golgin A4 | 0.0269551 |
| MMP2 | matrix metallopeptidase 2 | 0.0266996 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0265853 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0263446 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0260995 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0257773 |
| MORF4L2 | mortality factor 4 like 2 | 0.0257703 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0256804 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0252768 |
| AHR | aryl hydrocarbon receptor | 0.0250084 |
| RPL3 | ribosomal protein L3 | 0.0249604 |
| TMF1 | TATA element modulatory factor 1 | 0.0248099 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0247834 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 0.0246803 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0244523 |
| FMNL2 | formin-like 2 | 0.0238983 |
| ERBIN | erbb2 interacting protein | 0.0238012 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0236512 |
| KIF5B | kinesin family member 5B | 0.0234583 |
| GDF15 | growth differentiation factor 15 | 0.0232747 |
| VEGFA | vascular endothelial growth factor A | 0.023156 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0231441 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.023127 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.022826 |
| ANXA2 | annexin A2 | 0.0227877 |
| ARRDC3 | arrestin domain containing 3 | 0.0227147 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0225597 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0223049 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0222061 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0221597 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.022139 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0221123 |
| TOP1 | topoisomerase (DNA) I | 0.0220604 |
| CDC27 | cell division cycle 27 | 0.0220293 |
| WAC | WW domain containing adaptor with coiled-coil | 0.021989 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0217216 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0216 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0215833 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0214382 |
| CUL3 | cullin 3 | 0.0214078 |
| MBTD1 | mbt domain containing 1 | 0.0212289 |
| PDE8A | phosphodiesterase 8A | 0.0212206 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.0211412 |
| MKI67 | marker of proliferation Ki-67 | 0.0211378 |
| SEPTIN9 | septin 9 | 0.0209684 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0209628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.220598 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.14247 |
| NRG1 | neuregulin 1 | -0.118639 |
| COL1A1 | collagen, type I, alpha 1 | -0.117523 |
| LSAMP | limbic system-associated membrane protein | -0.0925047 |
| RPS6 | ribosomal protein S6 | -0.0879104 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0876299 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.079735 |
| SYT1 | synaptotagmin I | -0.0775902 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0731348 |
| ZNF804A | zinc finger protein 804A | -0.070821 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0691826 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0680273 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0663852 |
| CADM2 | cell adhesion molecule 2 | -0.0661419 |
| PCDH9 | protocadherin 9 | -0.0609684 |
| NREP | neuronal regeneration related protein | -0.0595239 |
| RPS24 | ribosomal protein S24 | -0.0593487 |
| FMN1 | formin 1 | -0.0592617 |
| RPL34 | ribosomal protein L34 | -0.0587212 |
| RPL19 | ribosomal protein L19 | -0.0585848 |
| KLHL13 | kelch-like family member 13 | -0.0578069 |
| RPL35A | ribosomal protein L35a | -0.0565797 |
| VIM | vimentin | -0.0542656 |
| RPL38 | ribosomal protein L38 | -0.0513872 |
| DTNA | dystrobrevin, alpha | -0.0511138 |
| ACTG1 | actin gamma 1 | -0.0510733 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0501672 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0493719 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0490417 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0487637 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0460475 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0452395 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0445151 |
| MEIS2 | Meis homeobox 2 | -0.0443593 |
| RPS19 | ribosomal protein S19 | -0.0443589 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0431866 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0420397 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.042019 |
| RPL27 | ribosomal protein L27 | -0.0411411 |
| RPLP1 | ribosomal protein, large, P1 | -0.0408111 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0404131 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0400969 |
| RPS11 | ribosomal protein S11 | -0.0396365 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0395408 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0394824 |
| HIP1 | huntingtin interacting protein 1 | -0.0385814 |
| RPS5 | ribosomal protein S5 | -0.0385019 |
| RPL31 | ribosomal protein L31 | -0.0382126 |
| MSI2 | musashi RNA-binding protein 2 | -0.0375797 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0375578 |
| IER3 | immediate early response 3 | -0.0369753 |
| AHNAK | AHNAK nucleoprotein | -0.0365658 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0363842 |
| MAP1B | microtubule-associated protein 1B | -0.0363558 |
| BPTF | bromodomain PHD finger transcription factor | -0.0361729 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0354612 |
| RPLP0 | ribosomal protein, large, P0 | -0.0352688 |
| RPS3 | ribosomal protein S3 | -0.0347788 |
| PTMA | prothymosin, alpha | -0.0344567 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0344204 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0341258 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0336943 |
| RPL36A | ribosomal protein L36a | -0.0327215 |
| DNM3 | dynamin 3 | -0.0326551 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0324562 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0321365 |
| RPL32 | ribosomal protein L32 | -0.0320444 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0320154 |
| SMYD3 | SET and MYND domain containing 3 | -0.0318633 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0318117 |
| NRP1 | neuropilin 1 | -0.0315941 |
| KLF6 | Kruppel-like factor 6 | -0.0313516 |
| FOXP1 | forkhead box P1 | -0.0310998 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0310457 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0309298 |
| ZNF609 | zinc finger protein 609 | -0.0302808 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0302366 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0296999 |
| NF1 | neurofibromin 1 | -0.0296641 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0296335 |
| RPS14 | ribosomal protein S14 | -0.0294288 |
| RBM39 | RNA binding motif protein 39 | -0.0293342 |
| SP100 | SP100 nuclear antigen | -0.0292251 |
| COL3A1 | collagen, type III, alpha 1 | -0.0289722 |
| TMSB10 | thymosin beta 10 | -0.0289383 |
| RPS8 | ribosomal protein S8 | -0.0287264 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284471 |
| CNTN4 | contactin 4 | -0.0281095 |
| CBX3 | chromobox homolog 3 | -0.027986 |
| DACH2 | dachshund family transcription factor 2 | -0.0278323 |
| CALD1 | caldesmon 1 | -0.0277049 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0276909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0276099 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0275727 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0273573 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0273119 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0273003 |
| CCND1 | cyclin D1 | -0.0267917 |
| CRH | corticotropin releasing hormone | -0.0267844 |
