| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.11499 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0936395 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0686308 |
| H1-0 | H1.0 linker histone | 0.0663845 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0570767 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.05687 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0567374 |
| SFTPA2 | surfactant protein A2 | 0.0564809 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0559008 |
| PHF3 | PHD finger protein 3 | 0.05589 |
| CCNL1 | cyclin L1 | 0.0550053 |
| SPATA13 | spermatogenesis associated 13 | 0.0536642 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0513204 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0509952 |
| NCKAP5 | NCK-associated protein 5 | 0.0470248 |
| RBM39 | RNA binding motif protein 39 | 0.0450814 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0448696 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0441122 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0435506 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0434648 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.043419 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.043042 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0409389 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0407742 |
| RAB6A | RAB6A, member RAS oncogene family | 0.040018 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.038922 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0383394 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0380638 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0373132 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0373022 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0370177 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0368618 |
| PRELID2 | PRELI domain containing 2 | 0.0368421 |
| USP54 | ubiquitin specific peptidase 54 | 0.0357424 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0354367 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0350717 |
| RAD51B | RAD51 paralog B | 0.0347482 |
| PGK1 | phosphoglycerate kinase 1 | 0.0342705 |
| TXNIP | thioredoxin interacting protein | 0.0340148 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0324763 |
| GOLGA2 | golgin A2 | 0.0316511 |
| MORF4L1 | mortality factor 4 like 1 | 0.0301003 |
| SQSTM1 | sequestosome 1 | 0.0294091 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0291149 |
| GOLGB1 | golgin B1 | 0.0277884 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0277521 |
| CTSB | cathepsin B | 0.0275008 |
| PTEN | phosphatase and tensin homolog | 0.0274922 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0274145 |
| RNF149 | ring finger protein 149 | 0.0272088 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0265771 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0263288 |
| APOL2 | apolipoprotein L, 2 | 0.0263177 |
| DST | dystonin | 0.0262911 |
| MLEC | malectin | 0.0260819 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0256534 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0255495 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0253894 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0253241 |
| OCLN | occludin | 0.0252123 |
| MYO10 | myosin X | 0.0251445 |
| FOXO3 | forkhead box O3 | 0.0250475 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0247791 |
| RBM26 | RNA binding motif protein 26 | 0.0247649 |
| ZNF395 | zinc finger protein 395 | 0.0245953 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.024357 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0243409 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0243376 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0243329 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.024264 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0236758 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0236607 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0235786 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0234425 |
| FNIP1 | folliculin interacting protein 1 | 0.02308 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0230715 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0230625 |
| ATP11B | ATPase, class VI, type 11B | 0.0228039 |
| SYT1 | synaptotagmin I | 0.0227974 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0227597 |
| DHFR | dihydrofolate reductase | 0.0227116 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0224893 |
| ARRDC3 | arrestin domain containing 3 | 0.0224385 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0221276 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0219914 |
| CSTB | cystatin B (stefin B) | 0.0216083 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0213949 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.021243 |
| EFHD2 | EF-hand domain family, member D2 | 0.0212002 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0210859 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0210339 |
| SP3 | Sp3 transcription factor | 0.020798 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.020779 |
| TAOK3 | TAO kinase 3 | 0.0207624 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0206879 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0205887 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0205819 |
| DENND4C | DENN/MADD domain containing 4C | 0.0205445 |
| CUL3 | cullin 3 | 0.0205207 |
| SLK | STE20-like kinase | 0.0204603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.203039 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.196042 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.151414 |
| LCN2 | lipocalin 2 | -0.142986 |
| PKM | pyruvate kinase, muscle | -0.0966062 |
| B2M | beta-2-microglobulin | -0.087788 |
| PTMA | prothymosin, alpha | -0.0821143 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.077192 |
| AHNAK | AHNAK nucleoprotein | -0.0754955 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0751043 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0698189 |
| MX1 | MX dynamin-like GTPase 1 | -0.068943 |
| LYZ | lysozyme | -0.0650056 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0645662 |
| RUNX1 | runt-related transcription factor 1 | -0.0644278 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0640882 |
| ACTG1 | actin gamma 1 | -0.0628517 |
| MX2 | MX dynamin-like GTPase 2 | -0.0604948 |
| RNF213 | ring finger protein 213 | -0.0597101 |
| POTEF | POTE ankyrin domain family, member F | -0.0591876 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0570575 |
| RPS6 | ribosomal protein S6 | -0.0563105 |
| HLA-B | major histocompatibility complex, class I, B | -0.0545806 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0511816 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0511224 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0506014 |
| PRKCA | protein kinase C, alpha | -0.0491173 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.048786 |
| JUN | jun proto-oncogene | -0.0479749 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0479208 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0476767 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.046548 |
| HLA-C | major histocompatibility complex, class I, C | -0.0459033 |
| RIGI | RNA sensor RIG-I | -0.0455418 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0455332 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0454644 |
| RPS27A | ribosomal protein S27a | -0.044813 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0433418 |
| TMSB10 | thymosin beta 10 | -0.0429206 |
| PERP | PERP, TP53 apoptosis effector | -0.0426825 |
| EXT1 | exostosin glycosyltransferase 1 | -0.04253 |
| SP100 | SP100 nuclear antigen | -0.0415339 |
| VMP1 | vacuole membrane protein 1 | -0.0410669 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0409557 |
| ENO1 | enolase 1, (alpha) | -0.0402201 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0394373 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0390131 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0379225 |
| FTL | ferritin, light polypeptide | -0.0370419 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0368517 |
| WWOX | WW domain containing oxidoreductase | -0.0365833 |
| LMO7 | LIM domain 7 | -0.0361771 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0359409 |
| DIAPH1 | diaphanous-related formin 1 | -0.0352615 |
| SETX | senataxin | -0.0347508 |
| SSH2 | slingshot protein phosphatase 2 | -0.034148 |
| CDHR2 | cadherin-related family member 2 | -0.0340955 |
| RPS8 | ribosomal protein S8 | -0.0339849 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0336857 |
| EZR | ezrin | -0.0336354 |
| LAMA4 | laminin, alpha 4 | -0.0330549 |
| RBM25 | RNA binding motif protein 25 | -0.0325337 |
| PLSCR1 | phospholipid scramblase 1 | -0.0321091 |
| MSI2 | musashi RNA-binding protein 2 | -0.0316805 |
| RRBP1 | ribosome binding protein 1 | -0.0311611 |
| S100A6 | S100 calcium binding protein A6 | -0.0310555 |
| RPL23 | ribosomal protein L23 | -0.0307571 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0290493 |
| ETV6 | ets variant 6 | -0.0289699 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.02894 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0284688 |
| HM13 | histocompatibility (minor) 13 | -0.0282914 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277558 |
| EPHB2 | EPH receptor B2 | -0.027601 |
| RPL19 | ribosomal protein L19 | -0.0275475 |
| RPL37A | ribosomal protein L37a | -0.027333 |
| TRERF1 | transcriptional regulating factor 1 | -0.0268133 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0267406 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0264977 |
| XAF1 | XIAP associated factor 1 | -0.0261129 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0257277 |
| RPS24 | ribosomal protein S24 | -0.0256572 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0254672 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0254079 |
| NPSR1 | neuropeptide S receptor 1 | -0.0253678 |
| TRIM2 | tripartite motif containing 2 | -0.0251809 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0251673 |
| KRT8 | keratin 8, type II | -0.0251306 |
| S100A10 | S100 calcium binding protein A10 | -0.0249385 |
| ANXA2 | annexin A2 | -0.0246822 |
| HMGB1 | high mobility group box 1 | -0.0246578 |
| LMNA | lamin A/C | -0.0245429 |
| FAT1 | FAT atypical cadherin 1 | -0.0245255 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0244955 |
| CALR | calreticulin | -0.0243373 |
| ZNRF3 | zinc and ring finger 3 | -0.0242006 |
| DEK | DEK proto-oncogene | -0.0241742 |
| PCBP2 | poly(rC) binding protein 2 | -0.0240716 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0239757 |
| RPS3 | ribosomal protein S3 | -0.0238691 |
