| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.172013 |
| FLNB | filamin B, beta | 0.0945691 |
| ENO1 | enolase 1, (alpha) | 0.0908538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0786379 |
| MSN | moesin | 0.0769081 |
| TPM3 | tropomyosin 3 | 0.0761744 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.066493 |
| MTSS1 | metastasis suppressor 1 | 0.0623007 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0616433 |
| EFHD2 | EF-hand domain family, member D2 | 0.0600673 |
| SET | SET nuclear proto-oncogene | 0.0537632 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0517459 |
| MCL1 | myeloid cell leukemia 1 | 0.0511551 |
| SULF1 | sulfatase 1 | 0.0509823 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0504008 |
| SLK | STE20-like kinase | 0.0503069 |
| SFTPA2 | surfactant protein A2 | 0.0500791 |
| PGK1 | phosphoglycerate kinase 1 | 0.0497112 |
| CALR | calreticulin | 0.0496354 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0479476 |
| PLEC | plectin | 0.0467902 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0453476 |
| ITGA6 | integrin, alpha 6 | 0.0448706 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0446441 |
| ASPH | aspartate beta-hydroxylase | 0.0436333 |
| LDHA | lactate dehydrogenase A | 0.0429551 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0421283 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0412635 |
| RPL3 | ribosomal protein L3 | 0.0393772 |
| CLU | clusterin | 0.0393175 |
| ANLN | anillin, actin binding protein | 0.0381827 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0381051 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0380544 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.037888 |
| RAI14 | retinoic acid induced 14 | 0.0377628 |
| GOLGA4 | golgin A4 | 0.0374343 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0371177 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.036758 |
| MYO10 | myosin X | 0.0362548 |
| NDRG1 | N-myc downstream regulated 1 | 0.0357116 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0356078 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0352523 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0343684 |
| RPS12 | ribosomal protein S12 | 0.0336555 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0335885 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0332856 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0332012 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0327001 |
| MEF2A | myocyte enhancer factor 2A | 0.032668 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0319003 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0313335 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0312228 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0307564 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0307332 |
| CEP250 | centrosomal protein 250kDa | 0.0302431 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0298649 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0296732 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0295331 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0291669 |
| ANXA11 | annexin A11 | 0.0291057 |
| LUZP1 | leucine zipper protein 1 | 0.0285138 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0284119 |
| NUP58 | nucleoporin 58 | 0.028336 |
| KRT6A | keratin 6A, type II | 0.0279327 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0278371 |
| PCDH1 | protocadherin 1 | 0.0276451 |
| LAMC2 | laminin, gamma 2 | 0.0276229 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.027413 |
| SMAD3 | SMAD family member 3 | 0.0272617 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0272229 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0270849 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0269511 |
| XPO1 | exportin 1 | 0.0269202 |
| DHFR | dihydrofolate reductase | 0.026717 |
| PODXL | podocalyxin-like | 0.0264991 |
| RBM26 | RNA binding motif protein 26 | 0.0264394 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0261967 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0259138 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0258843 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0258646 |
| DOK5 | docking protein 5 | 0.0257506 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0256707 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0255813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.025208 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.024745 |
| SEPTIN9 | septin 9 | 0.0245202 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0244639 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0244318 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0241838 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240861 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0240658 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0236956 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0236813 |
| OGA | O-GlcNAcase | 0.0234587 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.02325 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0230354 |
| CAPRIN2 | caprin family member 2 | 0.0230002 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0227723 |
| BLCAP | bladder cancer associated protein | 0.0225601 |
| IGF2 | insulin-like growth factor 2 | 0.0223781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.331183 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.134887 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.107095 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106483 |
| AHNAK | AHNAK nucleoprotein | -0.0978082 |
| EMP1 | epithelial membrane protein 1 | -0.0952646 |
| S100A10 | S100 calcium binding protein A10 | -0.0947644 |
| ANXA2 | annexin A2 | -0.0734101 |
| RPS21 | ribosomal protein S21 | -0.0708589 |
| LMO7 | LIM domain 7 | -0.0697141 |
| RPS6 | ribosomal protein S6 | -0.0696385 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.068193 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.064962 |
| POTEF | POTE ankyrin domain family, member F | -0.0610773 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0578024 |
| RPS24 | ribosomal protein S24 | -0.0568492 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.052672 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.046894 |
| ANXA1 | annexin A1 | -0.0466702 |
| LMNA | lamin A/C | -0.0459408 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0445036 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.044394 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436099 |
| GNAS | GNAS complex locus | -0.0425293 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0421733 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0419208 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0403441 |
| HLA-B | major histocompatibility complex, class I, B | -0.0400799 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.039143 |
| RPLP2 | ribosomal protein, large, P2 | -0.0390109 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0384608 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0382418 |
| OSMR | oncostatin M receptor | -0.0367335 |
| RPS25 | ribosomal protein S25 | -0.0362327 |
| H1-0 | H1.0 linker histone | -0.0360091 |
| RPS8 | ribosomal protein S8 | -0.0357625 |
| HLA-E | major histocompatibility complex, class I, E | -0.0356456 |
| IER3 | immediate early response 3 | -0.0355 |
| CD44 | CD44 molecule (Indian blood group) | -0.0354149 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0353084 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0348196 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0347622 |
| PALLD | palladin, cytoskeletal associated protein | -0.0343594 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0342689 |
| RPL8 | ribosomal protein L8 | -0.0340562 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.032819 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0311173 |
| SQLE | squalene epoxidase | -0.0308275 |
| TUBB | tubulin, beta class I | -0.0306854 |
| ARF1 | ADP-ribosylation factor 1 | -0.0306393 |
| CAVIN1 | caveolae associated protein 1 | -0.030361 |
| RPL28 | ribosomal protein L28 | -0.0300457 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0299328 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.029932 |
| RPLP0 | ribosomal protein, large, P0 | -0.0298246 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0297047 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0296371 |
| RPL27A | ribosomal protein L27a | -0.0295589 |
| RPS16 | ribosomal protein S16 | -0.028847 |
| RPS13 | ribosomal protein S13 | -0.0283568 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.028181 |
| RPS23 | ribosomal protein S23 | -0.0281227 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0278781 |
| RBM39 | RNA binding motif protein 39 | -0.0276632 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0274531 |
| PTMA | prothymosin, alpha | -0.0273833 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0271882 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0270667 |
| RPL39 | ribosomal protein L39 | -0.0270559 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0270365 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0269631 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0269161 |
| ACTG1 | actin gamma 1 | -0.0267607 |
| MTDH | metadherin | -0.0266916 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0264102 |
| EZR | ezrin | -0.0262069 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0258796 |
| CALU | calumenin | -0.0253586 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0251782 |
| NRG1 | neuregulin 1 | -0.0251068 |
| RPS5 | ribosomal protein S5 | -0.0251055 |
| FOXP1 | forkhead box P1 | -0.0250894 |
| RPS11 | ribosomal protein S11 | -0.0249336 |
| UBC | ubiquitin C | -0.0246153 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0245805 |
| ADIRF | adipogenesis regulatory factor | -0.0245362 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0245026 |
| JMJD1C | jumonji domain containing 1C | -0.0244205 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0244074 |
| TMSB10 | thymosin beta 10 | -0.0243609 |
| MECOM | MDS1 and EVI1 complex locus | -0.0243529 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0243405 |
| CCNI | cyclin I | -0.0242884 |
| EFNB2 | ephrin-B2 | -0.0242648 |
| ASTN2 | astrotactin 2 | -0.0241345 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0238497 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.023648 |
| RPL37 | ribosomal protein L37 | -0.0235344 |
| CD99 | CD99 molecule | -0.0235307 |
| RPL34 | ribosomal protein L34 | -0.0234957 |
