| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.137166 |
| FAT1 | FAT atypical cadherin 1 | 0.12702 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.113702 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.113442 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.109845 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.101169 |
| DSCAM | Down syndrome cell adhesion molecule | 0.095263 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0912037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0890609 |
| NDRG1 | N-myc downstream regulated 1 | 0.0865623 |
| EREG | epiregulin | 0.0864566 |
| DSPP | dentin sialophosphoprotein | 0.0863792 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0787954 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.078202 |
| PGK1 | phosphoglycerate kinase 1 | 0.0774935 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0768359 |
| EPCAM | epithelial cell adhesion molecule | 0.0763423 |
| ANXA2 | annexin A2 | 0.0718047 |
| PRELID2 | PRELI domain containing 2 | 0.0717665 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0714048 |
| CALR | calreticulin | 0.0689957 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0687103 |
| KRT8 | keratin 8, type II | 0.0685326 |
| ITGA6 | integrin, alpha 6 | 0.0627669 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0609357 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0601269 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0594994 |
| FAM13A | family with sequence similarity 13, member A | 0.0579703 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0572349 |
| MLEC | malectin | 0.0553206 |
| LMO7 | LIM domain 7 | 0.0550928 |
| EZR | ezrin | 0.0548661 |
| KRT18 | keratin 18, type I | 0.0542468 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0542101 |
| H1-0 | H1.0 linker histone | 0.054001 |
| ACTN4 | actinin, alpha 4 | 0.0527029 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0523858 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0503144 |
| KIF5B | kinesin family member 5B | 0.0502706 |
| PTEN | phosphatase and tensin homolog | 0.0497078 |
| TMSB4X | thymosin beta 4, X-linked | 0.0494671 |
| TXNIP | thioredoxin interacting protein | 0.0492096 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0491904 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0485405 |
| AREG | amphiregulin | 0.0484948 |
| AFDN | afadin, adherens junction formation factor | 0.0454699 |
| EHF | ets homologous factor | 0.04516 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0450726 |
| MUC13 | mucin 13, cell surface associated | 0.0447859 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0447609 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.044059 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0429212 |
| ASPH | aspartate beta-hydroxylase | 0.042669 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0420489 |
| MED13 | mediator complex subunit 13 | 0.0416803 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0409116 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0408229 |
| RPL7A | ribosomal protein L7a | 0.0405637 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0405381 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0403293 |
| FLNB | filamin B, beta | 0.0395968 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0393615 |
| TXNRD1 | thioredoxin reductase 1 | 0.0385413 |
| ENO1 | enolase 1, (alpha) | 0.0384576 |
| B2M | beta-2-microglobulin | 0.0376593 |
| RBM39 | RNA binding motif protein 39 | 0.0376509 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0371738 |
| PLAUR | plasminogen activator, urokinase receptor | 0.036965 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0369061 |
| GOLGA4 | golgin A4 | 0.036904 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0366909 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0366059 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0365217 |
| OGA | O-GlcNAcase | 0.0361431 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0359191 |
| TPM3 | tropomyosin 3 | 0.0349857 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0335632 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0326235 |
| ANXA11 | annexin A11 | 0.0324021 |
| SFTPA2 | surfactant protein A2 | 0.0323812 |
| MCL1 | myeloid cell leukemia 1 | 0.032062 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0320526 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0320047 |
| SET | SET nuclear proto-oncogene | 0.0317647 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0317095 |
| CUL3 | cullin 3 | 0.0315712 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0314849 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0314363 |
| CD46 | CD46 molecule, complement regulatory protein | 0.031382 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0311865 |
| CANX | calnexin | 0.0307986 |
| RPL7 | ribosomal protein L7 | 0.0306722 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0305815 |
| FNBP1L | formin binding protein 1-like | 0.0304467 |
| HELZ | helicase with zinc finger | 0.0303627 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0301786 |
| CTSB | cathepsin B | 0.0301752 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0299224 |
| APP | amyloid beta (A4) precursor protein | 0.0296444 |
| ZNF292 | zinc finger protein 292 | 0.0293594 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.179015 |
| TMSB10 | thymosin beta 10 | -0.142614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0966532 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0748614 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0642671 |
| POTEF | POTE ankyrin domain family, member F | -0.0588564 |
| RPS6 | ribosomal protein S6 | -0.0588154 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0550892 |
| ACTG1 | actin gamma 1 | -0.048493 |
| PTMA | prothymosin, alpha | -0.0454767 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0441809 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.043185 |
| GPHN | gephyrin | -0.0420041 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0399649 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0369745 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0357203 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0348085 |
| HMGA1 | high mobility group AT-hook 1 | -0.0332605 |
| MT2A | metallothionein 2A | -0.0318511 |
| MUC17 | mucin 17, cell surface associated | -0.0313561 |
| RPL35A | ribosomal protein L35a | -0.0311465 |
| MYO1E | myosin IE | -0.0298429 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0290372 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.02834 |
| RPL19 | ribosomal protein L19 | -0.0281838 |
| RPLP1 | ribosomal protein, large, P1 | -0.0276874 |
| RPLP2 | ribosomal protein, large, P2 | -0.027335 |
| CCND1 | cyclin D1 | -0.0268171 |
| HMGB1 | high mobility group box 1 | -0.0265551 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0262594 |
| NEBL | nebulette | -0.0260648 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.026044 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.025747 |
| VCL | vinculin | -0.0256185 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0245928 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0244739 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0244415 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239772 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0237782 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0235145 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0222909 |
| RPS8 | ribosomal protein S8 | -0.0220982 |
| FHIT | fragile histidine triad | -0.0216641 |
| RPL27 | ribosomal protein L27 | -0.0212892 |
| LSAMP | limbic system-associated membrane protein | -0.0212243 |
| AGR2 | anterior gradient 2 | -0.0210213 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0210111 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0206928 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0205207 |
| RPL21 | ribosomal protein L21 | -0.0201028 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0199584 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0193614 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0190738 |
| POU2F1 | POU class 2 homeobox 1 | -0.0189108 |
| RPL9 | ribosomal protein L9 | -0.0188053 |
| CCDC91 | coiled-coil domain containing 91 | -0.0186181 |
| RPL35 | ribosomal protein L35 | -0.0183999 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0181857 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0181839 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0181079 |
| RNF217 | ring finger protein 217 | -0.0179199 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0173761 |
| NRN1 | neuritin 1 | -0.0173673 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0171422 |
| RPL28 | ribosomal protein L28 | -0.0171277 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0170821 |
| GPR39 | G protein-coupled receptor 39 | -0.016669 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0165751 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0164322 |
| EGFR | epidermal growth factor receptor | -0.0162896 |
| ANTXR2 | anthrax toxin receptor 2 | -0.016261 |
| MECOM | MDS1 and EVI1 complex locus | -0.0159538 |
| MT1E | metallothionein 1E | -0.0157019 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0156872 |
| NRXN3 | neurexin 3 | -0.0156864 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0154562 |
| HELLS | helicase, lymphoid-specific | -0.0153763 |
| POF1B | premature ovarian failure, 1B | -0.0152532 |
| RPS5 | ribosomal protein S5 | -0.0152232 |
| TUBA1B | tubulin, alpha 1b | -0.0151523 |
| TFF1 | trefoil factor 1 | -0.0150853 |
| TUBB | tubulin, beta class I | -0.0149702 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.014961 |
| RPL34 | ribosomal protein L34 | -0.0149044 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0148647 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0146035 |
| RPL5 | ribosomal protein L5 | -0.0145498 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0145383 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0145071 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0144839 |
| RTN3 | reticulon 3 | -0.0143286 |
| PFN1 | profilin 1 | -0.0141868 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0140898 |
| RPL37A | ribosomal protein L37a | -0.0140589 |
| RNF145 | ring finger protein 145 | -0.0139496 |
| PKP4 | plakophilin 4 | -0.0138823 |
| SEC24D | SEC24 family member D | -0.0136805 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0136488 |
| RAD51B | RAD51 paralog B | -0.0135847 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0134492 |
