| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.139591 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.116885 |
| SET | SET nuclear proto-oncogene | 0.0986913 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0740881 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0735977 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0656891 |
| TMSB10 | thymosin beta 10 | 0.0643374 |
| LDHA | lactate dehydrogenase A | 0.0637525 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0631241 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0626778 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0609383 |
| TMSB4X | thymosin beta 4, X-linked | 0.0585935 |
| MT2A | metallothionein 2A | 0.0583062 |
| PGK1 | phosphoglycerate kinase 1 | 0.0568269 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.056692 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0541766 |
| CALR | calreticulin | 0.0537774 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.053268 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0524741 |
| MKI67 | marker of proliferation Ki-67 | 0.0512905 |
| RPL23 | ribosomal protein L23 | 0.0502685 |
| ENO1 | enolase 1, (alpha) | 0.0491153 |
| SPAG9 | sperm associated antigen 9 | 0.0477349 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0468773 |
| DST | dystonin | 0.0465172 |
| RAI1 | retinoic acid induced 1 | 0.0459369 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0447962 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0433537 |
| SFTPA2 | surfactant protein A2 | 0.043084 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.041498 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.041281 |
| SLK | STE20-like kinase | 0.0409866 |
| RPS12 | ribosomal protein S12 | 0.0405116 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0385737 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0377386 |
| TXNRD1 | thioredoxin reductase 1 | 0.0376323 |
| NUP58 | nucleoporin 58 | 0.0372753 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0371887 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0370771 |
| FTL | ferritin, light polypeptide | 0.0363125 |
| TPM3 | tropomyosin 3 | 0.0362751 |
| RPL3 | ribosomal protein L3 | 0.0361451 |
| CAPRIN2 | caprin family member 2 | 0.0355122 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0340907 |
| MT1X | metallothionein 1X | 0.032697 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0326106 |
| TMEM41B | transmembrane protein 41B | 0.0321063 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0314825 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0311939 |
| EZR | ezrin | 0.0308318 |
| ARRDC3 | arrestin domain containing 3 | 0.0308227 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0308107 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0302464 |
| GOLGA4 | golgin A4 | 0.029721 |
| CCNL1 | cyclin L1 | 0.0291647 |
| CENPF | centromere protein F, 350/400kDa | 0.0291169 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0290127 |
| HDGF | hepatoma-derived growth factor | 0.0286958 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0284903 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0283765 |
| CANX | calnexin | 0.0282321 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0281081 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0276897 |
| PRRC2C | proline-rich coiled-coil 2C | 0.027369 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0266997 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0262234 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0254005 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0251234 |
| YEATS2 | YEATS domain containing 2 | 0.0251126 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0250452 |
| MATR3 | matrin 3 | 0.0246714 |
| XPO1 | exportin 1 | 0.0246655 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0246458 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.024595 |
| PCBP2 | poly(rC) binding protein 2 | 0.0244996 |
| RACK1 | receptor for activated C kinase 1 | 0.0244744 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0244354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0244171 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0243148 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0242052 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0241683 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0239595 |
| RPS3 | ribosomal protein S3 | 0.0238403 |
| KIF5B | kinesin family member 5B | 0.023418 |
| MYOF | myoferlin | 0.0232809 |
| MCL1 | myeloid cell leukemia 1 | 0.0232521 |
| FNIP1 | folliculin interacting protein 1 | 0.0228844 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227499 |
| ANLN | anillin, actin binding protein | 0.0226498 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0224351 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.021873 |
| TPR | translocated promoter region, nuclear basket protein | 0.021805 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0217915 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0212047 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0210329 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0210179 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0210031 |
| RPS2 | ribosomal protein S2 | 0.020979 |
| YBX1 | Y box binding protein 1 | 0.0208277 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0208011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.381989 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132136 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0777933 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0743259 |
| CD44 | CD44 molecule (Indian blood group) | -0.0656528 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0573702 |
| HLA-B | major histocompatibility complex, class I, B | -0.0547394 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0520732 |
| TP63 | tumor protein p63 | -0.0516388 |
| AHNAK | AHNAK nucleoprotein | -0.0429277 |
| RPS24 | ribosomal protein S24 | -0.0427611 |
| CADM2 | cell adhesion molecule 2 | -0.0408224 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0370035 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0369168 |
| RPS6 | ribosomal protein S6 | -0.0352694 |
| SP100 | SP100 nuclear antigen | -0.0340698 |
| ACTG1 | actin gamma 1 | -0.0336474 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0317084 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0306215 |
| RPS23 | ribosomal protein S23 | -0.0294925 |
| FMNL2 | formin-like 2 | -0.0292213 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0291877 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0289242 |
| FUS | FUS RNA binding protein | -0.0278901 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0278335 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0275932 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0274147 |
| CFAP299 | cilia and flagella associated protein 299 | -0.026194 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0261656 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0261352 |
| RPL38 | ribosomal protein L38 | -0.0253678 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0251819 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0251479 |
| RUNX1 | runt-related transcription factor 1 | -0.0244452 |
| EXOC4 | exocyst complex component 4 | -0.0242999 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0237797 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0233867 |
| EMP1 | epithelial membrane protein 1 | -0.0227424 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0226582 |
| CDK6 | cyclin-dependent kinase 6 | -0.0221848 |
| ZNF217 | zinc finger protein 217 | -0.0221763 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0204567 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0204172 |
| CDK12 | cyclin-dependent kinase 12 | -0.0201184 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0199015 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0193493 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0193418 |
| ANXA2 | annexin A2 | -0.0192703 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0190682 |
| PDE10A | phosphodiesterase 10A | -0.0183008 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0182921 |
| RPL19 | ribosomal protein L19 | -0.0182012 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.017779 |
| TUBB | tubulin, beta class I | -0.0171897 |
| RPS29 | ribosomal protein S29 | -0.0170585 |
| GPHN | gephyrin | -0.0170456 |
| RPS15 | ribosomal protein S15 | -0.0164978 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0163476 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0161575 |
| RPLP0 | ribosomal protein, large, P0 | -0.016133 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0160023 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0157288 |
| SRGN | serglycin | -0.0156848 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0154787 |
| HMGB1 | high mobility group box 1 | -0.0153122 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0152446 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0149869 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0149743 |
| JMJD1C | jumonji domain containing 1C | -0.0149417 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0148108 |
| FOXN2 | forkhead box N2 | -0.0147958 |
| UBC | ubiquitin C | -0.0146507 |
| RIGI | RNA sensor RIG-I | -0.0146047 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0144876 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.014277 |
| OSMR | oncostatin M receptor | -0.0142626 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0140971 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0140304 |
| NF1 | neurofibromin 1 | -0.0140215 |
| GTF2B | general transcription factor IIB | -0.0138195 |
| CD2AP | CD2-associated protein | -0.013663 |
| ZNF609 | zinc finger protein 609 | -0.0136399 |
| PLSCR1 | phospholipid scramblase 1 | -0.0136225 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0136214 |
| RPS11 | ribosomal protein S11 | -0.0135544 |
| RGS4 | regulator of G-protein signaling 4 | -0.0135418 |
| LRRC23 | leucine rich repeat containing 23 | -0.0134744 |
| RPL28 | ribosomal protein L28 | -0.0134561 |
| INTS6 | integrator complex subunit 6 | -0.0134169 |
| TFRC | transferrin receptor | -0.0132748 |
| POTEF | POTE ankyrin domain family, member F | -0.0131948 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0131239 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0129605 |
| CUX1 | cut-like homeobox 1 | -0.0129396 |
| NPR2 | natriuretic peptide receptor 2 | -0.012773 |
| RPL36A | ribosomal protein L36a | -0.0127645 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0127164 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.012703 |
| TCF12 | transcription factor 12 | -0.0126992 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0126506 |
