| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.214168 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.16019 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.150929 |
| ASPH | aspartate beta-hydroxylase | 0.147631 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.140243 |
| NDRG1 | N-myc downstream regulated 1 | 0.13832 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.122621 |
| CALR | calreticulin | 0.111699 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.10437 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.101137 |
| LDHA | lactate dehydrogenase A | 0.0998467 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0989778 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0975471 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0971361 |
| HMGB2 | high mobility group box 2 | 0.0958991 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0936881 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0868135 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0791778 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.078995 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0789523 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0734242 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0733512 |
| LAMC2 | laminin, gamma 2 | 0.0726497 |
| CCNL1 | cyclin L1 | 0.0718949 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0690038 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0685922 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0674729 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0673549 |
| LAMB3 | laminin, beta 3 | 0.0654003 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.064705 |
| TMSB4X | thymosin beta 4, X-linked | 0.0637457 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0636438 |
| TPM3 | tropomyosin 3 | 0.0635645 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0604388 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0601492 |
| SFTPA2 | surfactant protein A2 | 0.0585509 |
| TFG | TRK-fused gene | 0.0585402 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0573854 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0565348 |
| ARRDC3 | arrestin domain containing 3 | 0.0564298 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0563423 |
| PGK1 | phosphoglycerate kinase 1 | 0.0559301 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0539957 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.051014 |
| CTSB | cathepsin B | 0.0491173 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0489993 |
| EPCAM | epithelial cell adhesion molecule | 0.0485416 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0469875 |
| SPAG9 | sperm associated antigen 9 | 0.0469165 |
| RAD21 | RAD21 homolog (S. pombe) | 0.046716 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0455856 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0452819 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0448953 |
| CLINT1 | clathrin interactor 1 | 0.0443647 |
| MCL1 | myeloid cell leukemia 1 | 0.0441708 |
| NUP58 | nucleoporin 58 | 0.04384 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0427396 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0426288 |
| SET | SET nuclear proto-oncogene | 0.042226 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0419959 |
| CANX | calnexin | 0.0417072 |
| ANXA1 | annexin A1 | 0.0416357 |
| PRRC2C | proline-rich coiled-coil 2C | 0.041481 |
| CDC73 | cell division cycle 73 | 0.0412323 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0408443 |
| FAM3C | family with sequence similarity 3, member C | 0.0406828 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0404896 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0403772 |
| APP | amyloid beta (A4) precursor protein | 0.0397427 |
| MATR3 | matrin 3 | 0.0394502 |
| PAPOLA | poly(A) polymerase alpha | 0.0392281 |
| ANXA5 | annexin A5 | 0.0390666 |
| RPL23 | ribosomal protein L23 | 0.0385909 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0382318 |
| MYO6 | myosin VI | 0.0379909 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0379113 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0378414 |
| TNPO1 | transportin 1 | 0.0376736 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0372047 |
| PCBP2 | poly(rC) binding protein 2 | 0.0371923 |
| PLEC | plectin | 0.0369589 |
| NCKAP1 | NCK-associated protein 1 | 0.036848 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0363812 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0363568 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0356567 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0352763 |
| MKI67 | marker of proliferation Ki-67 | 0.0348327 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0346203 |
| CNN3 | calponin 3, acidic | 0.0344563 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0344002 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0340831 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0339476 |
| ANLN | anillin, actin binding protein | 0.0333832 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0332534 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0332221 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0329506 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0328986 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0328959 |
| TXNRD1 | thioredoxin reductase 1 | 0.0326913 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0324444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193837 |
| POTEF | POTE ankyrin domain family, member F | -0.0714152 |
| ACTG1 | actin gamma 1 | -0.0642306 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0471921 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.047156 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0464609 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0421227 |
| FTL | ferritin, light polypeptide | -0.0415934 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0408405 |
| TMSB10 | thymosin beta 10 | -0.0364205 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345591 |
| RPS6 | ribosomal protein S6 | -0.0338375 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0338316 |
| GOLGB1 | golgin B1 | -0.0321943 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0321729 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0311081 |
| RPS8 | ribosomal protein S8 | -0.0309687 |
| AHNAK | AHNAK nucleoprotein | -0.030383 |
| MX2 | MX dynamin-like GTPase 2 | -0.0295139 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0278829 |
| RAD51B | RAD51 paralog B | -0.0275688 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0273337 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271319 |
| CCND1 | cyclin D1 | -0.0266132 |
| HLA-B | major histocompatibility complex, class I, B | -0.0259131 |
| RPL28 | ribosomal protein L28 | -0.0258725 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0253895 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0251504 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0240906 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0231709 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0231425 |
| RPS29 | ribosomal protein S29 | -0.0228783 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0223731 |
| S100A9 | S100 calcium binding protein A9 | -0.0220419 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0215545 |
| RPS14 | ribosomal protein S14 | -0.0206717 |
| MX1 | MX dynamin-like GTPase 1 | -0.0204831 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0203434 |
| CTSD | cathepsin D | -0.0203403 |
| NAV2 | neuron navigator 2 | -0.0202283 |
| RPS15 | ribosomal protein S15 | -0.0201809 |
| RAI14 | retinoic acid induced 14 | -0.0200619 |
| RPLP2 | ribosomal protein, large, P2 | -0.0200129 |
| HMGA1 | high mobility group AT-hook 1 | -0.0198762 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0198482 |
| FHIT | fragile histidine triad | -0.0198109 |
| RPL35A | ribosomal protein L35a | -0.0194954 |
| RPS10 | ribosomal protein S10 | -0.0189819 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0186262 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.01858 |
| EFNA5 | ephrin-A5 | -0.0185723 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0185528 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0185369 |
| RPL19 | ribosomal protein L19 | -0.0184377 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0182269 |
| CD2AP | CD2-associated protein | -0.0181216 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0180947 |
| ETV6 | ets variant 6 | -0.0179332 |
| KRT19 | keratin 19, type I | -0.0178301 |
| RPS23 | ribosomal protein S23 | -0.0166331 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0165169 |
| FBXO32 | F-box protein 32 | -0.0163702 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0163423 |
| DTNA | dystrobrevin, alpha | -0.0162599 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0160122 |
| RNF213 | ring finger protein 213 | -0.0158791 |
| VIM | vimentin | -0.0156365 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0156246 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0154749 |
| RIGI | RNA sensor RIG-I | -0.0153784 |
| BPTF | bromodomain PHD finger transcription factor | -0.0153667 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0152572 |
| SCFD1 | sec1 family domain containing 1 | -0.0151882 |
| RBM47 | RNA binding motif protein 47 | -0.0150795 |
| ATXN1 | ataxin 1 | -0.0149539 |
| RPL38 | ribosomal protein L38 | -0.0148576 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.014842 |
| EMP1 | epithelial membrane protein 1 | -0.0148188 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0146951 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0146766 |
| EXOC4 | exocyst complex component 4 | -0.0146507 |
| RSF1 | remodeling and spacing factor 1 | -0.0146493 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0146216 |
| RPS27A | ribosomal protein S27a | -0.0145684 |
| SEC24D | SEC24 family member D | -0.0144444 |
| SEC24A | SEC24 family member A | -0.0144185 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0143998 |
| BBX | bobby sox homolog (Drosophila) | -0.0143832 |
| HMGB1 | high mobility group box 1 | -0.0142435 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0140163 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0140052 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0139998 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0135217 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0134339 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0134051 |
| CUX1 | cut-like homeobox 1 | -0.0133754 |
| SHISA5 | shisa family member 5 | -0.0132703 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0131901 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0130922 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0130133 |
