| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.131084 |
| EFNA5 | ephrin-A5 | 0.104498 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0927342 |
| MCL1 | myeloid cell leukemia 1 | 0.0923949 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0898018 |
| DST | dystonin | 0.0766883 |
| ASPH | aspartate beta-hydroxylase | 0.0712191 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0681 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0675843 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0618957 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0605564 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0565726 |
| PGK1 | phosphoglycerate kinase 1 | 0.0558591 |
| FLNB | filamin B, beta | 0.0539173 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.048342 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0455701 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.045387 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0453484 |
| SFTPA2 | surfactant protein A2 | 0.0432136 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0415352 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0410069 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0409472 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0405888 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0402536 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0395742 |
| MYOF | myoferlin | 0.0388617 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0375436 |
| TXNRD1 | thioredoxin reductase 1 | 0.0370385 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0366884 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0361073 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0356227 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0347443 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0338651 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0330323 |
| GRAMD1B | GRAM domain containing 1B | 0.0328844 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0320118 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0319919 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317632 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.030911 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0302201 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301585 |
| TNPO1 | transportin 1 | 0.0297737 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0296377 |
| MKI67 | marker of proliferation Ki-67 | 0.0281011 |
| STC2 | stanniocalcin 2 | 0.0280994 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0280443 |
| PYGL | phosphorylase, glycogen, liver | 0.0271369 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0269724 |
| APP | amyloid beta (A4) precursor protein | 0.0268408 |
| BMERB1 | bMERB domain containing 1 | 0.0261257 |
| CANX | calnexin | 0.026027 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0259772 |
| PCBP3 | poly(rC) binding protein 3 | 0.0257907 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.025769 |
| CD109 | CD109 molecule | 0.0257266 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0253489 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0252029 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0251736 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0251136 |
| NDRG1 | N-myc downstream regulated 1 | 0.0248946 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0246851 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0241722 |
| OGA | O-GlcNAcase | 0.0241195 |
| TPM3 | tropomyosin 3 | 0.0239542 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0238693 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0225749 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0223199 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0220573 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0215603 |
| ENAH | enabled homolog (Drosophila) | 0.0213932 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.021183 |
| ERBIN | erbb2 interacting protein | 0.0211797 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0211711 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0210031 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0208656 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0208353 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0207884 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0204448 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0204251 |
| STC1 | stanniocalcin 1 | 0.0204038 |
| KIF5B | kinesin family member 5B | 0.0203771 |
| CUL3 | cullin 3 | 0.0203441 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0202795 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0201818 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.019828 |
| RPL3 | ribosomal protein L3 | 0.0197789 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0197507 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0197054 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.019544 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0191621 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0191078 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.018983 |
| LDHA | lactate dehydrogenase A | 0.0187542 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0186998 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0186929 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0185969 |
| PLCB4 | phospholipase C, beta 4 | 0.0183512 |
| CTSC | cathepsin C | 0.0182789 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.018256 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0182526 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266829 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.174749 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.116684 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0857298 |
| RPS6 | ribosomal protein S6 | -0.0800823 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0747593 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0650377 |
| FTL | ferritin, light polypeptide | -0.0641729 |
| RPLP1 | ribosomal protein, large, P1 | -0.056616 |
| TMSB10 | thymosin beta 10 | -0.0563016 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0523875 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0510437 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0506809 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0497859 |
| FN1 | fibronectin 1 | -0.0496812 |
| VIM | vimentin | -0.0466719 |
| PTMA | prothymosin, alpha | -0.0461663 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0444125 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0438714 |
| LSAMP | limbic system-associated membrane protein | -0.0432027 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0396014 |
| COL5A2 | collagen, type V, alpha 2 | -0.0396006 |
| RPS23 | ribosomal protein S23 | -0.0393431 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0393289 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0390036 |
| RPLP0 | ribosomal protein, large, P0 | -0.0372274 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.036527 |
| RPL19 | ribosomal protein L19 | -0.0357666 |
| RPS24 | ribosomal protein S24 | -0.0349901 |
| POTEF | POTE ankyrin domain family, member F | -0.0333948 |
| RPS8 | ribosomal protein S8 | -0.0327729 |
| RPL35A | ribosomal protein L35a | -0.0323825 |
| RPL9 | ribosomal protein L9 | -0.0314235 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0313683 |
| VDAC1 | voltage-dependent anion channel 1 | -0.031078 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0305257 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0304946 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303669 |
| RPL37A | ribosomal protein L37a | -0.0289261 |
| GNAS | GNAS complex locus | -0.0286925 |
| RPS19 | ribosomal protein S19 | -0.0286025 |
| RPL12 | ribosomal protein L12 | -0.028318 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0279973 |
| RPS14 | ribosomal protein S14 | -0.0278584 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0265766 |
| RPS25 | ribosomal protein S25 | -0.0263518 |
| S100A10 | S100 calcium binding protein A10 | -0.0248901 |
| RPS16 | ribosomal protein S16 | -0.0245238 |
| IL6 | interleukin 6 | -0.0243323 |
| FNDC3B | fibronectin type III domain containing 3B | -0.024247 |
| SRGN | serglycin | -0.0235416 |
| PKM | pyruvate kinase, muscle | -0.0234475 |
| RPLP2 | ribosomal protein, large, P2 | -0.0232531 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0229761 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0225512 |
| RPL28 | ribosomal protein L28 | -0.0225162 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0224999 |
| EGR1 | early growth response 1 | -0.0223077 |
| SMYD3 | SET and MYND domain containing 3 | -0.0221431 |
| TUBA1B | tubulin, alpha 1b | -0.0219438 |
| CADM2 | cell adhesion molecule 2 | -0.0218322 |
| RPS29 | ribosomal protein S29 | -0.0214851 |
| B2M | beta-2-microglobulin | -0.0209221 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0207128 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0206094 |
| RGS2 | regulator of G-protein signaling 2 | -0.0205461 |
| PCDH15 | protocadherin-related 15 | -0.0205411 |
| PALLD | palladin, cytoskeletal associated protein | -0.0204867 |
| MAP7 | microtubule-associated protein 7 | -0.0204333 |
| RPL31 | ribosomal protein L31 | -0.0203769 |
| RPL13A | ribosomal protein L13a | -0.0201525 |
| RPL27 | ribosomal protein L27 | -0.0200695 |
| PRKD3 | protein kinase D3 | -0.0200602 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0199847 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0195921 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0193792 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0191268 |
| RPL39 | ribosomal protein L39 | -0.0190823 |
| ACTG1 | actin gamma 1 | -0.0190081 |
| RPL34 | ribosomal protein L34 | -0.0189791 |
| NBEAL1 | neurobeachin-like 1 | -0.0188961 |
| LMNA | lamin A/C | -0.0188079 |
| KIAA0825 | KIAA0825 | -0.0186956 |
| IER3 | immediate early response 3 | -0.0186147 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0185422 |
| HLA-B | major histocompatibility complex, class I, B | -0.0184491 |
| RPL38 | ribosomal protein L38 | -0.0183772 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0181312 |
| PFN1 | profilin 1 | -0.0180091 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0179842 |
| RPS15 | ribosomal protein S15 | -0.0179647 |
| UBC | ubiquitin C | -0.0178255 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0178114 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | -0.0175959 |
| WDR45B | WD repeat domain 45B | -0.0173257 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0169155 |
| RPL36A | ribosomal protein L36a | -0.0168991 |
| MAGT1 | magnesium transporter 1 | -0.0168364 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0166462 |
| S100A6 | S100 calcium binding protein A6 | -0.0166078 |
