| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.123996 |
| SPAG9 | sperm associated antigen 9 | 0.114298 |
| PGK1 | phosphoglycerate kinase 1 | 0.105246 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0979162 |
| GOLGA4 | golgin A4 | 0.0931467 |
| RPLP2 | ribosomal protein, large, P2 | 0.0920878 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0868271 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0864466 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0861512 |
| RLF | rearranged L-myc fusion | 0.0859152 |
| NDRG1 | N-myc downstream regulated 1 | 0.0819331 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0818883 |
| PCM1 | pericentriolar material 1 | 0.0814066 |
| NOP58 | NOP58 ribonucleoprotein | 0.0797098 |
| NGLY1 | N-glycanase 1 | 0.0768561 |
| INHBA | inhibin, beta A | 0.0762319 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0760076 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0751473 |
| FTL | ferritin, light polypeptide | 0.0728336 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0717238 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0712232 |
| DSTN | destrin (actin depolymerizing factor) | 0.069004 |
| EGFR | epidermal growth factor receptor | 0.0688105 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0676202 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0642856 |
| SP3 | Sp3 transcription factor | 0.0625863 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.062094 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0614349 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0614093 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0614067 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0608513 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0606397 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0591881 |
| ACTN4 | actinin, alpha 4 | 0.0589781 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0585917 |
| TPD52 | tumor protein D52 | 0.0583236 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0582338 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0580015 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0570914 |
| TRAM1 | translocation associated membrane protein 1 | 0.0564699 |
| LOC112694756 | uncharaterized LOC112694756 | 0.055654 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0552193 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0546898 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0544149 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0543331 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.054175 |
| WDR45B | WD repeat domain 45B | 0.0537644 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0528415 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.052493 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0522487 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0516707 |
| NKTR | natural killer cell triggering receptor | 0.0511648 |
| H3-3B | H3.3 histone B | 0.0503726 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0500716 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0500317 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0498727 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0497157 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0479516 |
| RNF145 | ring finger protein 145 | 0.0473881 |
| COG5 | component of oligomeric golgi complex 5 | 0.047381 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0473568 |
| NUMB | numb homolog (Drosophila) | 0.0471635 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0469013 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0468876 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0468479 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.045392 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0447052 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0440591 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.043999 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0436866 |
| RTN4 | reticulon 4 | 0.0435743 |
| CUL3 | cullin 3 | 0.0434147 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0431986 |
| AHNAK | AHNAK nucleoprotein | 0.0430397 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.042793 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0418388 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0405969 |
| PCBP2 | poly(rC) binding protein 2 | 0.039971 |
| USP34 | ubiquitin specific peptidase 34 | 0.0398683 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.03979 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0394902 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0386501 |
| SEPTIN7 | septin 7 | 0.0379669 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0374772 |
| CCNL1 | cyclin L1 | 0.0372133 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0359392 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0358865 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0358197 |
| SET | SET nuclear proto-oncogene | 0.0355508 |
| PTK2 | protein tyrosine kinase 2 | 0.0349643 |
| DENND1A | DENN/MADD domain containing 1A | 0.0341638 |
| ZNF292 | zinc finger protein 292 | 0.0336107 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0334061 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0332499 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0322118 |
| TPR | translocated promoter region, nuclear basket protein | 0.0321149 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0320648 |
| ANKRD11 | ankyrin repeat domain 11 | 0.031921 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0318085 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0317258 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.223085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.143879 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.12037 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.117649 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.105817 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0885837 |
| TMSB10 | thymosin beta 10 | -0.0870385 |
| ASPH | aspartate beta-hydroxylase | -0.0859214 |
| EFNA5 | ephrin-A5 | -0.0844826 |
| RPS8 | ribosomal protein S8 | -0.0816535 |
| MYOF | myoferlin | -0.0771143 |
| POTEF | POTE ankyrin domain family, member F | -0.0768042 |
| RPL37A | ribosomal protein L37a | -0.0757185 |
| GPC6 | glypican 6 | -0.0740365 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0733888 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0702369 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0695316 |
| RPL35A | ribosomal protein L35a | -0.0686987 |
| PDE10A | phosphodiesterase 10A | -0.0686682 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0661331 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0607517 |
| PTMA | prothymosin, alpha | -0.0601334 |
| RPS6 | ribosomal protein S6 | -0.0600928 |
| ACTG1 | actin gamma 1 | -0.0577058 |
| MYO1E | myosin IE | -0.0564114 |
| SQSTM1 | sequestosome 1 | -0.0559946 |
| RPS27 | ribosomal protein S27 | -0.0545299 |
| OXR1 | oxidation resistance 1 | -0.054135 |
| BBX | bobby sox homolog (Drosophila) | -0.0532429 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0528452 |
| VMP1 | vacuole membrane protein 1 | -0.0524325 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0519506 |
| ENO1 | enolase 1, (alpha) | -0.0517277 |
| ZNF609 | zinc finger protein 609 | -0.0515198 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0504715 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.050264 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0493014 |
| JMJD1C | jumonji domain containing 1C | -0.0488344 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0487702 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0476104 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.045474 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0452942 |
| PRKCA | protein kinase C, alpha | -0.0446654 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0445788 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.043127 |
| KIF16B | kinesin family member 16B | -0.0422714 |
| HMGA1 | high mobility group AT-hook 1 | -0.0414881 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0411575 |
| VCL | vinculin | -0.0397324 |
| VIM | vimentin | -0.0394344 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0393972 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0393792 |
| CANX | calnexin | -0.0392225 |
| RUNX1 | runt-related transcription factor 1 | -0.0378306 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0369624 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0366341 |
| PDS5A | PDS5 cohesin associated factor A | -0.0365366 |
| CDH13 | cadherin 13 | -0.0361313 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0359403 |
| HELZ | helicase with zinc finger | -0.0351246 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0348968 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.034751 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0347506 |
| SIK3 | SIK family kinase 3 | -0.0333594 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0333522 |
| RORA | RAR-related orphan receptor A | -0.0333438 |
| RPS24 | ribosomal protein S24 | -0.0333338 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0331535 |
| PRELID2 | PRELI domain containing 2 | -0.0327074 |
| SCFD1 | sec1 family domain containing 1 | -0.0325196 |
| MEF2A | myocyte enhancer factor 2A | -0.0321989 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0320656 |
| SMYD3 | SET and MYND domain containing 3 | -0.0317985 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0315485 |
| ERBIN | erbb2 interacting protein | -0.0315198 |
| NAV2 | neuron navigator 2 | -0.0314856 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0314342 |
| HM13 | histocompatibility (minor) 13 | -0.0312692 |
| RAD51B | RAD51 paralog B | -0.0310854 |
| DST | dystonin | -0.0307044 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0305919 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0304967 |
| YEATS2 | YEATS domain containing 2 | -0.0302231 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0301499 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0301111 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0298061 |
| MED13L | mediator complex subunit 13-like | -0.0294152 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0292917 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0291874 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0287342 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0287116 |
| RPL7 | ribosomal protein L7 | -0.0283219 |
| GNAS | GNAS complex locus | -0.0276826 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0269427 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0263712 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0263328 |
| RPLP0 | ribosomal protein, large, P0 | -0.0261586 |
| ADNP | activity-dependent neuroprotector homeobox | -0.025995 |
| RPLP1 | ribosomal protein, large, P1 | -0.02596 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0258956 |
