| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.12038 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0900479 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0662427 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0624577 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0577343 |
| SRP54 | signal recognition particle 54kDa | 0.0568548 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0490984 |
| ZNF292 | zinc finger protein 292 | 0.048595 |
| WDR43 | WD repeat domain 43 | 0.0432445 |
| SPAG9 | sperm associated antigen 9 | 0.0428794 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0427737 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0425915 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0413541 |
| FBXO11 | F-box protein 11 | 0.040938 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.040608 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0394027 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0393325 |
| CCNL1 | cyclin L1 | 0.0385502 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0385379 |
| HDAC9 | histone deacetylase 9 | 0.0381258 |
| MYO10 | myosin X | 0.0380107 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0369703 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0369333 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0365051 |
| PRELID2 | PRELI domain containing 2 | 0.0360599 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0349189 |
| NCKAP1 | NCK-associated protein 1 | 0.0346433 |
| CFL2 | cofilin 2 (muscle) | 0.0344755 |
| ANXA1 | annexin A1 | 0.0344452 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.033636 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0330335 |
| ZNF608 | zinc finger protein 608 | 0.0328133 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0325913 |
| CALR | calreticulin | 0.032493 |
| RPL3 | ribosomal protein L3 | 0.0315517 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0309844 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0309031 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0307485 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0306513 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0294126 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0292797 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0288669 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0287365 |
| SLK | STE20-like kinase | 0.0282443 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0278945 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0278529 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0271919 |
| TENM2 | teneurin transmembrane protein 2 | 0.0270532 |
| RREB1 | ras responsive element binding protein 1 | 0.0270174 |
| MLEC | malectin | 0.0270121 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0268224 |
| QKI | QKI, KH domain containing, RNA binding | 0.0267111 |
| CERT1 | ceramide transporter 1 | 0.0267034 |
| COG6 | component of oligomeric golgi complex 6 | 0.0266152 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0264607 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0261256 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0260262 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0258731 |
| ANXA5 | annexin A5 | 0.0253409 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0250378 |
| LPIN2 | lipin 2 | 0.0250139 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0244709 |
| SP3 | Sp3 transcription factor | 0.0242826 |
| LYST | lysosomal trafficking regulator | 0.0240672 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0240319 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0239637 |
| VMP1 | vacuole membrane protein 1 | 0.0239395 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0233816 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0232867 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0230577 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0229639 |
| FNIP1 | folliculin interacting protein 1 | 0.022743 |
| PRR16 | proline rich 16 | 0.0227103 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0226222 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0225983 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0225161 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0224121 |
| COL5A2 | collagen, type V, alpha 2 | 0.0222006 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0221514 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0221259 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0220827 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0220747 |
| MB21D2 | Mab-21 domain containing 2 | 0.0219061 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0217978 |
| NUP58 | nucleoporin 58 | 0.0217804 |
| FOCAD | focadhesin | 0.0217301 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0211611 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0209401 |
| PNN | pinin, desmosome associated protein | 0.0209189 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0209149 |
| KIAA1958 | KIAA1958 | 0.0208746 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0207264 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0206419 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0205453 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0205096 |
| FAM168A | family with sequence similarity 168, member A | 0.0203424 |
| GPC4 | glypican 4 | 0.0202346 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.020227 |
| INSIG2 | insulin induced gene 2 | 0.0201208 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0199826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157163 |
| VIM | vimentin | -0.152216 |
| RPS16 | ribosomal protein S16 | -0.129225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121078 |
| PTMA | prothymosin, alpha | -0.119738 |
| ACTG1 | actin gamma 1 | -0.114547 |
| TMSB10 | thymosin beta 10 | -0.100019 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0979425 |
| POTEF | POTE ankyrin domain family, member F | -0.0838422 |
| RPS8 | ribosomal protein S8 | -0.0830827 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0816021 |
| RPS6 | ribosomal protein S6 | -0.0782399 |
| GNAS | GNAS complex locus | -0.076943 |
| RPLP1 | ribosomal protein, large, P1 | -0.0753536 |
| EMP1 | epithelial membrane protein 1 | -0.0724275 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0711988 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0694144 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0672487 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0644824 |
| PCDH9 | protocadherin 9 | -0.0617298 |
| AHNAK | AHNAK nucleoprotein | -0.0603178 |
| UBC | ubiquitin C | -0.0600045 |
| RPS21 | ribosomal protein S21 | -0.0580037 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0545466 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0512998 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0501022 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0479758 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.04794 |
| RPL19 | ribosomal protein L19 | -0.0476636 |
| GPC3 | glypican 3 | -0.0467358 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.045526 |
| FOXP2 | forkhead box P2 | -0.0449232 |
| TOX | thymocyte selection-associated high mobility group box | -0.0448596 |
| RPL12 | ribosomal protein L12 | -0.0438731 |
| TMSB4X | thymosin beta 4, X-linked | -0.0433656 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0432298 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0431591 |
| RPS24 | ribosomal protein S24 | -0.0427019 |
| S100A10 | S100 calcium binding protein A10 | -0.0425331 |
| TUBA1B | tubulin, alpha 1b | -0.0423882 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0408348 |
| RPS3 | ribosomal protein S3 | -0.0407083 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0406551 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0395346 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.039121 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0390321 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0387251 |
| RLF | rearranged L-myc fusion | -0.0386624 |
| HMGB1 | high mobility group box 1 | -0.0384875 |
| RPL34 | ribosomal protein L34 | -0.0380086 |
| CDK12 | cyclin-dependent kinase 12 | -0.0379831 |
| TJP1 | tight junction protein 1 | -0.0375985 |
| RPL9 | ribosomal protein L9 | -0.0374339 |
| RPS27A | ribosomal protein S27a | -0.0363372 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0361271 |
| TENM3 | teneurin transmembrane protein 3 | -0.0349243 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0341253 |
| PHIP | pleckstrin homology domain interacting protein | -0.033971 |
| RPLP0 | ribosomal protein, large, P0 | -0.0338238 |
| POU3F2 | POU class 3 homeobox 2 | -0.0334292 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0326369 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0325615 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0325019 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0319999 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0317098 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0317004 |
| RBM25 | RNA binding motif protein 25 | -0.0314897 |
| NPAS3 | neuronal PAS domain protein 3 | -0.031348 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0313108 |
| TPX2 | TPX2, microtubule-associated | -0.0313092 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0310996 |
| CDH19 | cadherin 19, type 2 | -0.0310326 |
| KNL1 | kinetochore scaffold 1 | -0.0309164 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0309057 |
| COL3A1 | collagen, type III, alpha 1 | -0.0307576 |
| RPS5 | ribosomal protein S5 | -0.030249 |
| CENPE | centromere protein E, 312kDa | -0.0301369 |
| RBM39 | RNA binding motif protein 39 | -0.0300655 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0296504 |
| RPS15 | ribosomal protein S15 | -0.0295773 |
| TPR | translocated promoter region, nuclear basket protein | -0.0295434 |
| RPL38 | ribosomal protein L38 | -0.029446 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0294382 |
| URI1 | URI1, prefoldin-like chaperone | -0.0293081 |
| CADM2 | cell adhesion molecule 2 | -0.0289579 |
| KIF4A | kinesin family member 4A | -0.0288452 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0285919 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0282702 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0282695 |
| FAM171B | family with sequence similarity 171, member B | -0.0282358 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0281947 |
| RAD51B | RAD51 paralog B | -0.0280447 |
| RPL28 | ribosomal protein L28 | -0.027549 |
| RPL31 | ribosomal protein L31 | -0.0274925 |
| RPL32 | ribosomal protein L32 | -0.0274107 |
| RTN4 | reticulon 4 | -0.0273484 |
| SRP72 | signal recognition particle 72kDa | -0.0266127 |
| TUBB | tubulin, beta class I | -0.0264379 |
| FBL | fibrillarin | -0.0264277 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0263101 |
