| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.123461 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.112823 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0958843 |
| PGK1 | phosphoglycerate kinase 1 | 0.0790927 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0703513 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0678714 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0660346 |
| LDHA | lactate dehydrogenase A | 0.0619712 |
| ENO1 | enolase 1, (alpha) | 0.060833 |
| TXNRD1 | thioredoxin reductase 1 | 0.0606713 |
| GOLGA4 | golgin A4 | 0.0601099 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0587582 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0587534 |
| MKI67 | marker of proliferation Ki-67 | 0.0548158 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0539125 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0533458 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0498742 |
| SET | SET nuclear proto-oncogene | 0.0495767 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0493765 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0491781 |
| FLNB | filamin B, beta | 0.0486585 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0483524 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0483302 |
| PRELID2 | PRELI domain containing 2 | 0.0465926 |
| RBM39 | RNA binding motif protein 39 | 0.0457167 |
| RPL3 | ribosomal protein L3 | 0.0447538 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0444743 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0435166 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0435137 |
| TXNIP | thioredoxin interacting protein | 0.043503 |
| SFTPA2 | surfactant protein A2 | 0.0434705 |
| CENPF | centromere protein F, 350/400kDa | 0.0428645 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0426587 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0416651 |
| ANK2 | ankyrin 2, neuronal | 0.0412217 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.040906 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0406407 |
| PYGB | phosphorylase, glycogen; brain | 0.0403723 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0395484 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0392964 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0392128 |
| CALR | calreticulin | 0.0390809 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.038496 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0372684 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0369758 |
| B2M | beta-2-microglobulin | 0.0363805 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.036097 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0356241 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0351223 |
| NUP58 | nucleoporin 58 | 0.0347264 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.034095 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0340723 |
| NCKAP1 | NCK-associated protein 1 | 0.0338042 |
| TMEM65 | transmembrane protein 65 | 0.0330683 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0328355 |
| HMGB2 | high mobility group box 2 | 0.0325582 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0324866 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.032464 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320079 |
| TMF1 | TATA element modulatory factor 1 | 0.0319813 |
| KIF5B | kinesin family member 5B | 0.0314539 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0309776 |
| ANXA1 | annexin A1 | 0.0309456 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0299269 |
| HJURP | Holliday junction recognition protein | 0.0298698 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0298643 |
| EZR | ezrin | 0.0296876 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0294151 |
| XPO1 | exportin 1 | 0.0293315 |
| FAM13A | family with sequence similarity 13, member A | 0.0291305 |
| PLK2 | polo-like kinase 2 | 0.0288344 |
| SPAG9 | sperm associated antigen 9 | 0.0281255 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0279591 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0275875 |
| TPM4 | tropomyosin 4 | 0.0275329 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0275147 |
| YEATS2 | YEATS domain containing 2 | 0.0273387 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0273366 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0271215 |
| ANKRD11 | ankyrin repeat domain 11 | 0.027115 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0271074 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0270661 |
| ZNF292 | zinc finger protein 292 | 0.0266308 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0264338 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0264093 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.026231 |
| TMEM41B | transmembrane protein 41B | 0.026083 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0252522 |
| RPL23 | ribosomal protein L23 | 0.0250954 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0249886 |
| MCL1 | myeloid cell leukemia 1 | 0.0249834 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.024951 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0247843 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0244769 |
| WDR43 | WD repeat domain 43 | 0.0244135 |
| CKAP2 | cytoskeleton associated protein 2 | 0.024335 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0241956 |
| HDLBP | high density lipoprotein binding protein | 0.0241372 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0239393 |
| MORF4L2 | mortality factor 4 like 2 | 0.0237998 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180937 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.107774 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0844747 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0841658 |
| FOXP1 | forkhead box P1 | -0.0824668 |
| RPS6 | ribosomal protein S6 | -0.0657152 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0626948 |
| ACTG1 | actin gamma 1 | -0.0537724 |
| PKM | pyruvate kinase, muscle | -0.0518469 |
| NBEA | neurobeachin | -0.045788 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0455678 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0381906 |
| EGFR | epidermal growth factor receptor | -0.0356585 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0356232 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0346186 |
| GLI3 | GLI family zinc finger 3 | -0.0339382 |
| POTEF | POTE ankyrin domain family, member F | -0.033425 |
| RPL9 | ribosomal protein L9 | -0.0314375 |
| RPS8 | ribosomal protein S8 | -0.0305529 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0252368 |
| RPS16 | ribosomal protein S16 | -0.0249968 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0248937 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0232334 |
| PDE7B | phosphodiesterase 7B | -0.0229517 |
| RPS29 | ribosomal protein S29 | -0.022273 |
| GPHN | gephyrin | -0.0212279 |
| RPLP1 | ribosomal protein, large, P1 | -0.0207465 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0206563 |
| RPL34 | ribosomal protein L34 | -0.0198357 |
| NFIA | nuclear factor I/A | -0.0198251 |
| RPS23 | ribosomal protein S23 | -0.0197768 |
| RPLP2 | ribosomal protein, large, P2 | -0.0192753 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0191461 |
| RPS10 | ribosomal protein S10 | -0.0186315 |
| RPL35A | ribosomal protein L35a | -0.0185187 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0182137 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0180819 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0177556 |
| RPS20 | ribosomal protein S20 | -0.0174699 |
| MYO5C | myosin VC | -0.0173696 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.017035 |
| RPL35 | ribosomal protein L35 | -0.0170096 |
| RPS14 | ribosomal protein S14 | -0.0168667 |
| RPL28 | ribosomal protein L28 | -0.0167821 |
| NMD3 | NMD3 ribosome export adaptor | -0.016761 |
| EXOC4 | exocyst complex component 4 | -0.0163975 |
| RPL19 | ribosomal protein L19 | -0.0162727 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0162083 |
| MACROD2 | MACRO domain containing 2 | -0.0160062 |
| RPS5 | ribosomal protein S5 | -0.0159513 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0158948 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0158396 |
| RIGI | RNA sensor RIG-I | -0.015432 |
| RPS25 | ribosomal protein S25 | -0.0153072 |
| CCND1 | cyclin D1 | -0.0151947 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0151216 |
| TASOR2 | transcription activation suppressor family member 2 | -0.014957 |
| TUBB | tubulin, beta class I | -0.0149435 |
| FUS | FUS RNA binding protein | -0.0149341 |
| RPS21 | ribosomal protein S21 | -0.014926 |
| WWOX | WW domain containing oxidoreductase | -0.0145908 |
| MTAP | methylthioadenosine phosphorylase | -0.0144722 |
| CEP112 | centrosomal protein 112kDa | -0.0143302 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0143237 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0142635 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0141842 |
| BPTF | bromodomain PHD finger transcription factor | -0.0137744 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0137428 |
| RPS15 | ribosomal protein S15 | -0.0136398 |
| RPS11 | ribosomal protein S11 | -0.0132797 |
| ZNF438 | zinc finger protein 438 | -0.013218 |
| RPS24 | ribosomal protein S24 | -0.0131879 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.013169 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0131184 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0130403 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0130394 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.01285 |
| RPL13A | ribosomal protein L13a | -0.0128414 |
| APLF | aprataxin and PNKP like factor | -0.0127381 |
| EXOC2 | exocyst complex component 2 | -0.0127237 |
| UBB | ubiquitin B | -0.0127051 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.012653 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0122929 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0122522 |
| ONECUT2 | one cut homeobox 2 | -0.0122156 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0121655 |
| BMP10 | bone morphogenetic protein 10 | -0.0121646 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0120744 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.012007 |
| RPS13 | ribosomal protein S13 | -0.0118271 |
| RPL38 | ribosomal protein L38 | -0.0117039 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0116912 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0116305 |
| XXYLT1 | xyloside xylosyltransferase 1 | -0.0114859 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0114461 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0114449 |
| TDRD3 | tudor domain containing 3 | -0.0114417 |
| MCPH1 | microcephalin 1 | -0.0114379 |
| S100A10 | S100 calcium binding protein A10 | -0.0113917 |
| TMSB10 | thymosin beta 10 | -0.011389 |
