| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.298765 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.219221 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.160476 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.146433 |
| SFTPA2 | surfactant protein A2 | 0.131717 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101547 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0841575 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0810898 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0806351 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0772545 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0725788 |
| MKI67 | marker of proliferation Ki-67 | 0.071057 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0661763 |
| PGK1 | phosphoglycerate kinase 1 | 0.065395 |
| DST | dystonin | 0.0641528 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0618393 |
| OGA | O-GlcNAcase | 0.0607824 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0602418 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0601046 |
| SPAG9 | sperm associated antigen 9 | 0.0583789 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0582055 |
| ANLN | anillin, actin binding protein | 0.0579558 |
| FN1 | fibronectin 1 | 0.054616 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0539163 |
| ARRDC3 | arrestin domain containing 3 | 0.0524782 |
| NAV2 | neuron navigator 2 | 0.0524283 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.050615 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0501987 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0500193 |
| LDHA | lactate dehydrogenase A | 0.0499117 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0480766 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0474275 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0454701 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0450471 |
| GOLGA4 | golgin A4 | 0.0424125 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0413711 |
| CALR | calreticulin | 0.041335 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0408961 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0403289 |
| CENPF | centromere protein F, 350/400kDa | 0.0397921 |
| APP | amyloid beta (A4) precursor protein | 0.0393412 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0370204 |
| CKAP5 | cytoskeleton associated protein 5 | 0.036756 |
| CEP250 | centrosomal protein 250kDa | 0.036454 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0349644 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0348618 |
| SET | SET nuclear proto-oncogene | 0.0333013 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0330983 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0326961 |
| TPM3 | tropomyosin 3 | 0.032647 |
| MATR3 | matrin 3 | 0.0324131 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0320054 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0319204 |
| JMJD1C | jumonji domain containing 1C | 0.0315325 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0313001 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0309729 |
| CDK19 | cyclin-dependent kinase 19 | 0.0306223 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0305552 |
| DIAPH3 | diaphanous-related formin 3 | 0.0303613 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0302948 |
| ATP13A3 | ATPase type 13A3 | 0.0302676 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0301543 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0289786 |
| RPS12 | ribosomal protein S12 | 0.0288858 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0287484 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0286434 |
| SERINC1 | serine incorporator 1 | 0.0280229 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0279349 |
| MORF4L2 | mortality factor 4 like 2 | 0.0272852 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0269939 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0268698 |
| MCL1 | myeloid cell leukemia 1 | 0.0265782 |
| GGNBP2 | gametogenetin binding protein 2 | 0.02651 |
| KIF4A | kinesin family member 4A | 0.026347 |
| PTMA | prothymosin, alpha | 0.0262027 |
| WTAP | Wilms tumor 1 associated protein | 0.0260919 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0260482 |
| DENND5A | DENN/MADD domain containing 5A | 0.0255946 |
| OPTN | optineurin | 0.0254822 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0254395 |
| AFDN | afadin, adherens junction formation factor | 0.0254109 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0253656 |
| KPNB1 | karyopherin (importin) beta 1 | 0.025214 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0250725 |
| IPO7 | importin 7 | 0.0250146 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0248039 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.024518 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0242559 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0242427 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0240798 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0238114 |
| KIF5B | kinesin family member 5B | 0.0232085 |
| SNX9 | sorting nexin 9 | 0.0232065 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0231937 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0229054 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0228943 |
| USP37 | ubiquitin specific peptidase 37 | 0.0228777 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0228614 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0227202 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0225469 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295332 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.118931 |
| FRMD4A | FERM domain containing 4A | -0.0961705 |
| FTL | ferritin, light polypeptide | -0.0839891 |
| IER3 | immediate early response 3 | -0.0824903 |
| GLIS3 | GLIS family zinc finger 3 | -0.0799488 |
| RPS6 | ribosomal protein S6 | -0.0712174 |
| HLA-B | major histocompatibility complex, class I, B | -0.0710991 |
| HMGA2 | high mobility group AT-hook 2 | -0.0678363 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0642849 |
| VIM | vimentin | -0.0638756 |
| TMSB10 | thymosin beta 10 | -0.0638221 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0575641 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0526809 |
| CTSD | cathepsin D | -0.046694 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0460052 |
| RPS23 | ribosomal protein S23 | -0.0446978 |
| BICC1 | BicC family RNA binding protein 1 | -0.044355 |
| ACTG1 | actin gamma 1 | -0.0431222 |
| NAV1 | neuron navigator 1 | -0.0426631 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0425257 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0404221 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.038601 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0341578 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0340146 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0336468 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0333896 |
| CDH13 | cadherin 13 | -0.0332461 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0329375 |
| MT2A | metallothionein 2A | -0.0328293 |
| RPLP2 | ribosomal protein, large, P2 | -0.0325339 |
| QKI | QKI, KH domain containing, RNA binding | -0.032217 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319475 |
| EGR1 | early growth response 1 | -0.0317742 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0307925 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0306775 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0306601 |
| TAPBP | TAP binding protein (tapasin) | -0.0305857 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0298902 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0297448 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0295235 |
| RPS24 | ribosomal protein S24 | -0.0291949 |
| INTS6 | integrator complex subunit 6 | -0.0290551 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286612 |
| RPL28 | ribosomal protein L28 | -0.0286503 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0285173 |
| TUBB | tubulin, beta class I | -0.0284344 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0284205 |
| RPL19 | ribosomal protein L19 | -0.0282782 |
| RPS10 | ribosomal protein S10 | -0.027759 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0276736 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274011 |
| HLA-A | major histocompatibility complex, class I, A | -0.0273287 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0272463 |
| RNF213 | ring finger protein 213 | -0.026321 |
| RPLP0 | ribosomal protein, large, P0 | -0.0262961 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0261736 |
| TNS3 | tensin 3 | -0.0258687 |
| AHNAK | AHNAK nucleoprotein | -0.0256671 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0256393 |
| PKM | pyruvate kinase, muscle | -0.0255432 |
| RPS8 | ribosomal protein S8 | -0.0255352 |
| TENM2 | teneurin transmembrane protein 2 | -0.0254083 |
| RPS19 | ribosomal protein S19 | -0.0250291 |
| ASTN2 | astrotactin 2 | -0.0249167 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0246277 |
| TPM1 | tropomyosin 1 (alpha) | -0.0243109 |
| RIGI | RNA sensor RIG-I | -0.024062 |
| GPC6 | glypican 6 | -0.0239057 |
| POTEF | POTE ankyrin domain family, member F | -0.0235505 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0234339 |
| RPL5 | ribosomal protein L5 | -0.022769 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0226713 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0226682 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0221733 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0221162 |
| RPL9 | ribosomal protein L9 | -0.0213578 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.02126 |
| RPS20 | ribosomal protein S20 | -0.0212437 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0211033 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0210595 |
| RPS14 | ribosomal protein S14 | -0.0210251 |
| DIAPH2 | diaphanous-related formin 2 | -0.0208263 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0208207 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0206606 |
| XAF1 | XIAP associated factor 1 | -0.0204981 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0204462 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0203152 |
| MAP1B | microtubule-associated protein 1B | -0.0200685 |
| RPS29 | ribosomal protein S29 | -0.0198898 |
| BNC2 | basonuclin 2 | -0.0198498 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0197211 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0196805 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0194914 |
| HMGA1 | high mobility group AT-hook 1 | -0.019059 |
| TMEM132D | transmembrane protein 132D | -0.0190452 |
| RPL38 | ribosomal protein L38 | -0.0187462 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0186593 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0186546 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0184847 |
