| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.17841 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.174254 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.117495 |
| MT2A | metallothionein 2A | 0.0954017 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0860366 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0839868 |
| ZNF292 | zinc finger protein 292 | 0.0826025 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0792281 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0741441 |
| NDRG1 | N-myc downstream regulated 1 | 0.0724257 |
| CALR | calreticulin | 0.071066 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0690901 |
| FAM13A | family with sequence similarity 13, member A | 0.0688217 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0670705 |
| ANLN | anillin, actin binding protein | 0.0645242 |
| OGA | O-GlcNAcase | 0.0620739 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0602826 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.057098 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.054389 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0528956 |
| FLNA | filamin A, alpha | 0.0526217 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0482962 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0470656 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0459524 |
| NUP58 | nucleoporin 58 | 0.0455914 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0452767 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0448762 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0432602 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0429713 |
| MATR3 | matrin 3 | 0.0425253 |
| LOC112694756 | uncharaterized LOC112694756 | 0.041711 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0409309 |
| INSIG2 | insulin induced gene 2 | 0.040801 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0407182 |
| TFG | TRK-fused gene | 0.0404921 |
| STC1 | stanniocalcin 1 | 0.0401946 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0401698 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0397292 |
| EFNA5 | ephrin-A5 | 0.0395997 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0392203 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0391593 |
| FMNL2 | formin-like 2 | 0.0389394 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0386655 |
| HMGB2 | high mobility group box 2 | 0.0385279 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0384883 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0381963 |
| THBS1 | thrombospondin 1 | 0.0378119 |
| B2M | beta-2-microglobulin | 0.0374271 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0373336 |
| PGK1 | phosphoglycerate kinase 1 | 0.0371103 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0366506 |
| RNF24 | ring finger protein 24 | 0.0355523 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0352789 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.035025 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0350143 |
| XPO1 | exportin 1 | 0.0349779 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0343347 |
| ARRDC3 | arrestin domain containing 3 | 0.0341522 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.033973 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0338944 |
| MED13L | mediator complex subunit 13-like | 0.0337236 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0332719 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0330114 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0328108 |
| SPAG9 | sperm associated antigen 9 | 0.032759 |
| TPD52 | tumor protein D52 | 0.0326869 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0326315 |
| MT1X | metallothionein 1X | 0.0323843 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0323424 |
| PDE10A | phosphodiesterase 10A | 0.0323318 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0322152 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0319812 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0317537 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0316463 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0311573 |
| LAMB1 | laminin, beta 1 | 0.0306192 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0305371 |
| FOXJ3 | forkhead box J3 | 0.0300476 |
| MTF2 | metal response element binding transcription factor 2 | 0.0299842 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0298604 |
| RPL8 | ribosomal protein L8 | 0.0294547 |
| VMP1 | vacuole membrane protein 1 | 0.0293036 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0292396 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0291309 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0288761 |
| ABI1 | abl-interactor 1 | 0.0285745 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0285356 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0284455 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0283628 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283527 |
| RSF1 | remodeling and spacing factor 1 | 0.0281899 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0280239 |
| CFDP1 | craniofacial development protein 1 | 0.0279183 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0278576 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0278484 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0278469 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0278301 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0273779 |
| SP100 | SP100 nuclear antigen | 0.0272069 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0269978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.226509 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.142497 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134573 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114133 |
| CDH13 | cadherin 13 | -0.0968021 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0949717 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.076069 |
| COL1A2 | collagen, type I, alpha 2 | -0.0737476 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0716746 |
| POTEF | POTE ankyrin domain family, member F | -0.0675893 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0662165 |
| EGFR | epidermal growth factor receptor | -0.0653477 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0625103 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0596944 |
| MAP1B | microtubule-associated protein 1B | -0.0594495 |
| IL6 | interleukin 6 | -0.0573937 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0524567 |
| CDK6 | cyclin-dependent kinase 6 | -0.0518995 |
| FN1 | fibronectin 1 | -0.0496752 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0459979 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0451245 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0447366 |
| UBC | ubiquitin C | -0.044266 |
| TMEM165 | transmembrane protein 165 | -0.0441547 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0429883 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0421714 |
| HLA-A | major histocompatibility complex, class I, A | -0.0415709 |
| CALU | calumenin | -0.0412243 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0405958 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0383455 |
| TNS3 | tensin 3 | -0.0380703 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0379634 |
| COL1A1 | collagen, type I, alpha 1 | -0.0367415 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0365419 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0363785 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0354 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0343366 |
| NAV1 | neuron navigator 1 | -0.034037 |
| KAZN | kazrin, periplakin interacting protein | -0.0339995 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0335547 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.033354 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0316144 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0315873 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0313247 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0311901 |
| GLIS3 | GLIS family zinc finger 3 | -0.031151 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0308637 |
| TPM2 | tropomyosin 2 (beta) | -0.0298823 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0298639 |
| PTMA | prothymosin, alpha | -0.0293652 |
| CLINT1 | clathrin interactor 1 | -0.0292982 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0292399 |
| RPL28 | ribosomal protein L28 | -0.0287567 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.028211 |
| CADM1 | cell adhesion molecule 1 | -0.0281747 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0281448 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0281367 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0278123 |
| BBX | bobby sox homolog (Drosophila) | -0.0270912 |
| FTL | ferritin, light polypeptide | -0.0269412 |
| PGM3 | phosphoglucomutase 3 | -0.0266063 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0264232 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0262745 |
| GPR173 | G protein-coupled receptor 173 | -0.0261714 |
| ATF4 | activating transcription factor 4 | -0.0257697 |
| NKTR | natural killer cell triggering receptor | -0.0257427 |
| HLA-C | major histocompatibility complex, class I, C | -0.0256262 |
| DIAPH3 | diaphanous-related formin 3 | -0.0254192 |
| HDAC9 | histone deacetylase 9 | -0.0253 |
| ECE1 | endothelin converting enzyme 1 | -0.0251456 |
| COL5A2 | collagen, type V, alpha 2 | -0.0250414 |
| ARF4 | ADP-ribosylation factor 4 | -0.0249155 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0245929 |
| IRF1 | interferon regulatory factor 1 | -0.0245903 |
| BRD4 | bromodomain containing 4 | -0.0244405 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0244299 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0242934 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.0241853 |
| GSE1 | Gse1 coiled-coil protein | -0.0240865 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0239522 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0238316 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0236662 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0236109 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0232776 |
| TPM1 | tropomyosin 1 (alpha) | -0.0230006 |
| VEGFC | vascular endothelial growth factor C | -0.0228627 |
| ITGAV | integrin, alpha V | -0.0228118 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0226761 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0225811 |
| PFN1 | profilin 1 | -0.0225278 |
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | -0.0224178 |
| MTDH | metadherin | -0.0223998 |
| MYADM | myeloid-associated differentiation marker | -0.0222574 |
| FRMD4A | FERM domain containing 4A | -0.0221091 |
| GRB10 | growth factor receptor-bound protein 10 | -0.021945 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0218637 |
| NBAS | neuroblastoma amplified sequence | -0.0218589 |
| KIF13A | kinesin family member 13A | -0.0217822 |
| SEPTIN7 | septin 7 | -0.0217042 |
| CDK13 | cyclin-dependent kinase 13 | -0.0214513 |
