| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.104602 |
| TXNRD1 | thioredoxin reductase 1 | 0.071969 |
| RBM39 | RNA binding motif protein 39 | 0.068426 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0658799 |
| ANKRD28 | ankyrin repeat domain 28 | 0.064818 |
| SMC4 | structural maintenance of chromosomes 4 | 0.062678 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0606829 |
| SET | SET nuclear proto-oncogene | 0.0604482 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0598517 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.059432 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0590605 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0577746 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0548495 |
| CENPF | centromere protein F, 350/400kDa | 0.0536521 |
| CLTC | clathrin, heavy chain (Hc) | 0.0528045 |
| ZNF292 | zinc finger protein 292 | 0.0520358 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0519201 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0501958 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0501167 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0498037 |
| ANLN | anillin, actin binding protein | 0.0491608 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0490835 |
| NUP58 | nucleoporin 58 | 0.0488615 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0487152 |
| DIAPH3 | diaphanous-related formin 3 | 0.0486365 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0477847 |
| TPX2 | TPX2, microtubule-associated | 0.0475718 |
| MKI67 | marker of proliferation Ki-67 | 0.0471308 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0462901 |
| GOLGA4 | golgin A4 | 0.0462381 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0459984 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0457122 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0443293 |
| KIAA1958 | KIAA1958 | 0.0417855 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0413368 |
| IPO7 | importin 7 | 0.0412272 |
| MATR3 | matrin 3 | 0.0402011 |
| ECT2 | epithelial cell transforming 2 | 0.0385982 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0384012 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0361676 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0358911 |
| YBX3 | Y box binding protein 3 | 0.035449 |
| CANX | calnexin | 0.0353689 |
| KIF5B | kinesin family member 5B | 0.0349238 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0344019 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0342835 |
| SPAG9 | sperm associated antigen 9 | 0.0332945 |
| RDX | radixin | 0.0332912 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0326305 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0326274 |
| PHIP | pleckstrin homology domain interacting protein | 0.0326033 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0323827 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0322384 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0320009 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0319053 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0318015 |
| ATXN2 | ataxin 2 | 0.0317548 |
| TTK | TTK protein kinase | 0.0305023 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0303731 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0303699 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0301278 |
| CALR | calreticulin | 0.0301166 |
| HSPA8 | heat shock 70kDa protein 8 | 0.029899 |
| SETD5 | SET domain containing 5 | 0.0298674 |
| CALU | calumenin | 0.0298401 |
| MORF4L2 | mortality factor 4 like 2 | 0.0297637 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0292773 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0289599 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0288677 |
| PHF3 | PHD finger protein 3 | 0.0282117 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0281493 |
| ARRDC3 | arrestin domain containing 3 | 0.0281372 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0278451 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0278329 |
| PRR11 | proline rich 11 | 0.0275554 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0274913 |
| CENPE | centromere protein E, 312kDa | 0.0274205 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.027296 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0270463 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0268864 |
| TBK1 | TANK-binding kinase 1 | 0.0268187 |
| GOLT1B | golgi transport 1B | 0.0267464 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0265188 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0264608 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0263958 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0261282 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0259259 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0258168 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0258163 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0257728 |
| TNPO1 | transportin 1 | 0.0254394 |
| CEP250 | centrosomal protein 250kDa | 0.0253869 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0253606 |
| CEP295 | centrosomal protein 295kDa | 0.0251659 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0250885 |
| TFG | TRK-fused gene | 0.0249213 |
| SFXN1 | sideroflexin 1 | 0.0248759 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0246613 |
| WBP11 | WW domain binding protein 11 | 0.0246512 |
| TPM3 | tropomyosin 3 | 0.0245794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.206561 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.117775 |
| FNDC3B | fibronectin type III domain containing 3B | -0.11109 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.111057 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0983032 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0968185 |
| HMGA2 | high mobility group AT-hook 2 | -0.082222 |
| TMSB10 | thymosin beta 10 | -0.0818154 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0778077 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0673587 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0659253 |
| RIGI | RNA sensor RIG-I | -0.065663 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0638489 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0629429 |
| ANGPTL4 | angiopoietin-like 4 | -0.0623205 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0602718 |
| RAI14 | retinoic acid induced 14 | -0.058962 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0572217 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0567139 |
| PTMA | prothymosin, alpha | -0.0552262 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0539525 |
| DST | dystonin | -0.053762 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0535852 |
| RAD51B | RAD51 paralog B | -0.0534823 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0534467 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0521436 |
| INTS6 | integrator complex subunit 6 | -0.0506591 |
| CD44 | CD44 molecule (Indian blood group) | -0.0503038 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0495926 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0489053 |
| POTEF | POTE ankyrin domain family, member F | -0.0476032 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0472559 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0469585 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0464153 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0456702 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0442571 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0440372 |
| ATXN1 | ataxin 1 | -0.0436226 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0433547 |
| EGR1 | early growth response 1 | -0.043064 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0426506 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0412459 |
| PRKCA | protein kinase C, alpha | -0.0409673 |
| ANKRD11 | ankyrin repeat domain 11 | -0.040929 |
| FMN1 | formin 1 | -0.0406154 |
| PCED1B | PC-esterase domain containing 1B | -0.0405495 |
| SVIL | supervillin | -0.0392985 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0385996 |
| IER3 | immediate early response 3 | -0.0385321 |
| FN1 | fibronectin 1 | -0.038431 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0380862 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0375274 |
| EXT1 | exostosin glycosyltransferase 1 | -0.03736 |
| MYOF | myoferlin | -0.0360828 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0358715 |
| AHNAK | AHNAK nucleoprotein | -0.0357437 |
| IGF2 | insulin-like growth factor 2 | -0.0354448 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0353999 |
| USP34 | ubiquitin specific peptidase 34 | -0.0351413 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0350372 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0348557 |
| PCNX4 | pecanex 4 | -0.0347901 |
| PKM | pyruvate kinase, muscle | -0.0347131 |
| GPC5 | glypican 5 | -0.0345913 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0344031 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0343833 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0343123 |
| MYO9B | myosin IXB | -0.0337642 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0337553 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0336601 |
| ATM | ATM serine/threonine kinase | -0.0335709 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0335259 |
| PTK2 | protein tyrosine kinase 2 | -0.0335015 |
| LRRC49 | leucine rich repeat containing 49 | -0.0328588 |
| ATG7 | autophagy related 7 | -0.0326038 |
| RPLP1 | ribosomal protein, large, P1 | -0.0325823 |
| AOPEP | aminopeptidase O (putative) | -0.0325159 |
| HLA-A | major histocompatibility complex, class I, A | -0.0320811 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0312447 |
| ABR | active BCR-related | -0.0312085 |
| ZNF638 | zinc finger protein 638 | -0.0307289 |
| MYO10 | myosin X | -0.0306942 |
| ZNF609 | zinc finger protein 609 | -0.0306772 |
| AEBP2 | AE binding protein 2 | -0.0304424 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0304194 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0303502 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.030287 |
| WWOX | WW domain containing oxidoreductase | -0.0300117 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0299063 |
| PARD3 | par-3 family cell polarity regulator | -0.0294098 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.029273 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | -0.0281116 |
| EGFR | epidermal growth factor receptor | -0.02801 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0279728 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0276342 |
| SDC4 | syndecan 4 | -0.0276017 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0275802 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.027495 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0274765 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.027449 |
