| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ataluren perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ataluren_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.144068 |
| NDRG1 | N-myc downstream regulated 1 | 0.135438 |
| SFTPA2 | surfactant protein A2 | 0.113455 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0962279 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0888857 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0847997 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0840662 |
| CD109 | CD109 molecule | 0.0739644 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0702756 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0666573 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0646296 |
| FAM13A | family with sequence similarity 13, member A | 0.0633986 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0620538 |
| TXNIP | thioredoxin interacting protein | 0.0595606 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0591237 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0590434 |
| CANX | calnexin | 0.0585091 |
| CALR | calreticulin | 0.0564364 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0559279 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0548792 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0547962 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0546849 |
| AHR | aryl hydrocarbon receptor | 0.0530307 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0517433 |
| ZNF292 | zinc finger protein 292 | 0.0498206 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0496451 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0495548 |
| PLIN2 | perilipin 2 | 0.0456875 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0454256 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0453681 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0450455 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0442932 |
| B2M | beta-2-microglobulin | 0.0439676 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0435547 |
| TPR | translocated promoter region, nuclear basket protein | 0.0434527 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0433182 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0414341 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0411815 |
| SPAG9 | sperm associated antigen 9 | 0.0404502 |
| GOLGA4 | golgin A4 | 0.0401952 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0401447 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0400881 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0400544 |
| NUP58 | nucleoporin 58 | 0.0396408 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0394213 |
| RBM39 | RNA binding motif protein 39 | 0.0392089 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0384408 |
| WAC | WW domain containing adaptor with coiled-coil | 0.03815 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0379249 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0378177 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0377442 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0374718 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0373539 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0372109 |
| TPM3 | tropomyosin 3 | 0.036851 |
| CCNL1 | cyclin L1 | 0.0364382 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.036389 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0355549 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0346372 |
| ARRDC3 | arrestin domain containing 3 | 0.0343053 |
| STC2 | stanniocalcin 2 | 0.0337762 |
| NEK7 | NIMA-related kinase 7 | 0.0333385 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0329829 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0329216 |
| XPO1 | exportin 1 | 0.0326674 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0323499 |
| PCBP2 | poly(rC) binding protein 2 | 0.032303 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0322154 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0318281 |
| TFG | TRK-fused gene | 0.0315338 |
| CLINT1 | clathrin interactor 1 | 0.0312227 |
| RNF145 | ring finger protein 145 | 0.0308101 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0305488 |
| GLUL | glutamate-ammonia ligase | 0.0305251 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0304272 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0301396 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0298278 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0297564 |
| ANXA5 | annexin A5 | 0.029708 |
| CEP350 | centrosomal protein 350kDa | 0.0296823 |
| FAT1 | FAT atypical cadherin 1 | 0.0293768 |
| VEGFA | vascular endothelial growth factor A | 0.0291622 |
| CALU | calumenin | 0.0289767 |
| SFXN1 | sideroflexin 1 | 0.0289097 |
| FBXO32 | F-box protein 32 | 0.0287993 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0286021 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0284646 |
| TPD52 | tumor protein D52 | 0.0284164 |
| LDHA | lactate dehydrogenase A | 0.0283102 |
| INSIG2 | insulin induced gene 2 | 0.0280314 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0279612 |
| SUCO | SUN domain containing ossification factor | 0.0278573 |
| TXNRD1 | thioredoxin reductase 1 | 0.0278177 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0271849 |
| MATR3 | matrin 3 | 0.0270285 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0268919 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0267449 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0265337 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0262423 |
| TMF1 | TATA element modulatory factor 1 | 0.0258011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.290561 |
| FN1 | fibronectin 1 | -0.213182 |
| NRG1 | neuregulin 1 | -0.186735 |
| VCL | vinculin | -0.0859928 |
| HMGA2 | high mobility group AT-hook 2 | -0.0850649 |
| SYT1 | synaptotagmin I | -0.0786337 |
| NTN4 | netrin 4 | -0.062237 |
| SQSTM1 | sequestosome 1 | -0.0605035 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0579355 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0566179 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0540718 |
| GLIS3 | GLIS family zinc finger 3 | -0.0527799 |
| NRP1 | neuropilin 1 | -0.050586 |
| PTMA | prothymosin, alpha | -0.0482058 |
| HLA-B | major histocompatibility complex, class I, B | -0.0469888 |
| TMSB10 | thymosin beta 10 | -0.0438823 |
| ASPH | aspartate beta-hydroxylase | -0.0434371 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0422707 |
| ITGA1 | integrin, alpha 1 | -0.0407267 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0405432 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039968 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0397559 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0387786 |
| PALLD | palladin, cytoskeletal associated protein | -0.0387563 |
| MAP1B | microtubule-associated protein 1B | -0.0380269 |
| ACTG1 | actin gamma 1 | -0.0372508 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0360147 |
| RPS6 | ribosomal protein S6 | -0.035436 |
| RIGI | RNA sensor RIG-I | -0.0348567 |
| RNF213 | ring finger protein 213 | -0.0337712 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0329008 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0327124 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0308872 |
| NXN | nucleoredoxin | -0.0306109 |
| TNS3 | tensin 3 | -0.0283302 |
| OSMR | oncostatin M receptor | -0.0281516 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0278247 |
| INTS6 | integrator complex subunit 6 | -0.0271034 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0267688 |
| MX2 | MX dynamin-like GTPase 2 | -0.0266177 |
| AHNAK | AHNAK nucleoprotein | -0.0262693 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0255593 |
| RPS24 | ribosomal protein S24 | -0.0254506 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0251072 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0250845 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0250049 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0249378 |
| FHL2 | four and a half LIM domains 2 | -0.0248331 |
| RPL38 | ribosomal protein L38 | -0.0245342 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0239464 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0233235 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0232942 |
| AEBP2 | AE binding protein 2 | -0.0232491 |
| SEPTIN9 | septin 9 | -0.0230942 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0229707 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0224016 |
| FOXP1 | forkhead box P1 | -0.0222953 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0218467 |
| SP100 | SP100 nuclear antigen | -0.0215066 |
| VCAN | versican | -0.0214242 |
| KLHL5 | kelch-like family member 5 | -0.0212315 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0212303 |
| EGR1 | early growth response 1 | -0.020635 |
| RPL35A | ribosomal protein L35a | -0.0205321 |
| IFI44L | interferon-induced protein 44-like | -0.0204981 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.020333 |
| IER3 | immediate early response 3 | -0.0201425 |
| RAB31 | RAB31, member RAS oncogene family | -0.0201348 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0200961 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0199314 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0198337 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.01977 |
| CUX1 | cut-like homeobox 1 | -0.0197608 |
| RANBP17 | RAN binding protein 17 | -0.0195991 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0193295 |
| RASAL2 | RAS protein activator like 2 | -0.0192378 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0191533 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0190958 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0189743 |
| MYO10 | myosin X | -0.0189607 |
| ETV1 | ets variant 1 | -0.0187839 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0186792 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.018255 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0181122 |
| HMGA1 | high mobility group AT-hook 1 | -0.0180597 |
| RPS5 | ribosomal protein S5 | -0.0180245 |
| KIAA1217 | KIAA1217 | -0.0179604 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0178619 |
| HMGB1 | high mobility group box 1 | -0.0176715 |
| UBXN4 | UBX domain protein 4 | -0.0174634 |
| XAF1 | XIAP associated factor 1 | -0.0174271 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0172198 |
| MX1 | MX dynamin-like GTPase 1 | -0.0171766 |
| BPTF | bromodomain PHD finger transcription factor | -0.0170438 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0169033 |
| KRT81 | keratin 81, type II | -0.0168916 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0167928 |
| RAB10 | RAB10, member RAS oncogene family | -0.0166508 |
| EFNA5 | ephrin-A5 | -0.01649 |
| GLCCI1 | glucocorticoid induced 1 | -0.0164431 |
