| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Atazanavir (sulfate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Atazanavir (sulfate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.169194 |
| FBN1 | fibrillin 1 | 0.151427 |
| LOXL2 | lysyl oxidase-like 2 | 0.125503 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.122472 |
| LOX | lysyl oxidase | 0.118961 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.115921 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.114677 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.110143 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.102928 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.09992 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0965748 |
| COL1A2 | collagen, type I, alpha 2 | 0.092677 |
| UBC | ubiquitin C | 0.0885497 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0772266 |
| COL5A2 | collagen, type V, alpha 2 | 0.0723171 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0706071 |
| COL3A1 | collagen, type III, alpha 1 | 0.070506 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.070396 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0686373 |
| AUTS2 | autism susceptibility candidate 2 | 0.0683627 |
| OGA | O-GlcNAcase | 0.067065 |
| ATP13A3 | ATPase type 13A3 | 0.061975 |
| SBF2 | SET binding factor 2 | 0.061903 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0560502 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0560271 |
| STC1 | stanniocalcin 1 | 0.0555169 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0542439 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.053989 |
| FLNB | filamin B, beta | 0.0536797 |
| APP | amyloid beta (A4) precursor protein | 0.05296 |
| THBS2 | thrombospondin 2 | 0.0527605 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0520575 |
| OPTN | optineurin | 0.0518349 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0510622 |
| GPC6 | glypican 6 | 0.0498356 |
| PLAT | plasminogen activator, tissue | 0.0479064 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0478829 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0478111 |
| GOLGA4 | golgin A4 | 0.0453485 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0449845 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0439097 |
| SETD5 | SET domain containing 5 | 0.0438126 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0436521 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0434388 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.043154 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0430828 |
| FNIP1 | folliculin interacting protein 1 | 0.0419071 |
| GOLGA2 | golgin A2 | 0.041874 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0411352 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0406318 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0403061 |
| DENND5A | DENN/MADD domain containing 5A | 0.0396999 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0396478 |
| SEPTIN9 | septin 9 | 0.0387261 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0383504 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0376327 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0363897 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0363179 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0361302 |
| YEATS2 | YEATS domain containing 2 | 0.0354783 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0354372 |
| WTAP | Wilms tumor 1 associated protein | 0.0354364 |
| DST | dystonin | 0.0353859 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0353079 |
| SLC22A23 | solute carrier family 22, member 23 | 0.035113 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0348808 |
| AFDN | afadin, adherens junction formation factor | 0.0347335 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0342768 |
| FNBP4 | formin binding protein 4 | 0.0340991 |
| CD109 | CD109 molecule | 0.0339309 |
| ARRDC3 | arrestin domain containing 3 | 0.0338194 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0337874 |
| NAV2 | neuron navigator 2 | 0.0337506 |
| B2M | beta-2-microglobulin | 0.0335914 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0335837 |
| HIP1 | huntingtin interacting protein 1 | 0.0335274 |
| ITSN2 | intersectin 2 | 0.0333267 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0331654 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0326164 |
| MMP12 | matrix metallopeptidase 12 | 0.0322782 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0321871 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0318553 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0318399 |
| CLU | clusterin | 0.0316004 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0313964 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0311345 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0307233 |
| USP34 | ubiquitin specific peptidase 34 | 0.0306859 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0306387 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0302405 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0299907 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0298416 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0298118 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0297423 |
| NDRG1 | N-myc downstream regulated 1 | 0.0295184 |
| TMOD1 | tropomodulin 1 | 0.0294231 |
| STK10 | serine/threonine kinase 10 | 0.0293431 |
| PCGF5 | polycomb group ring finger 5 | 0.0291016 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0289812 |
| SFTPA2 | surfactant protein A2 | 0.0289641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.200054 |
| CDH13 | cadherin 13 | -0.113659 |
| POTEF | POTE ankyrin domain family, member F | -0.113159 |
| TMSB10 | thymosin beta 10 | -0.111065 |
| S100A10 | S100 calcium binding protein A10 | -0.0998676 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0865698 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0812202 |
| PODXL | podocalyxin-like | -0.0780568 |
| MAP1B | microtubule-associated protein 1B | -0.0766487 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0714772 |
| TPM4 | tropomyosin 4 | -0.067707 |
| FN1 | fibronectin 1 | -0.0626866 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0591468 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0527532 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0494628 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0469626 |
| SUCNR1 | succinate receptor 1 | -0.0447484 |
| ASPH | aspartate beta-hydroxylase | -0.0440622 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0436015 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0410712 |
| CENPF | centromere protein F, 350/400kDa | -0.0404499 |
| EGFR | epidermal growth factor receptor | -0.0404284 |
| CCND1 | cyclin D1 | -0.0395215 |
| ENO1 | enolase 1, (alpha) | -0.0391774 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0389271 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0386552 |
| AHNAK | AHNAK nucleoprotein | -0.0380673 |
| RIGI | RNA sensor RIG-I | -0.0365254 |
| LRRC17 | leucine rich repeat containing 17 | -0.0365138 |
| RPS8 | ribosomal protein S8 | -0.0364187 |
| MX2 | MX dynamin-like GTPase 2 | -0.0356881 |
| RPL35A | ribosomal protein L35a | -0.0352017 |
| NAV1 | neuron navigator 1 | -0.0348692 |
| PLXNA2 | plexin A2 | -0.0343303 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0341634 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0336524 |
| RPLP1 | ribosomal protein, large, P1 | -0.0333527 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0332552 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0331222 |
| RPL28 | ribosomal protein L28 | -0.0330862 |
| ACTG1 | actin gamma 1 | -0.0329122 |
| RPS6 | ribosomal protein S6 | -0.0324475 |
| EFNA5 | ephrin-A5 | -0.0317829 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0317382 |
| PKM | pyruvate kinase, muscle | -0.0313986 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0310279 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0305342 |
| IL7R | interleukin 7 receptor | -0.0305018 |
| RPL37A | ribosomal protein L37a | -0.0303176 |
| SP100 | SP100 nuclear antigen | -0.0301914 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0299919 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0299406 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0298004 |
| RPS24 | ribosomal protein S24 | -0.0295885 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0294311 |
| CUX1 | cut-like homeobox 1 | -0.0288021 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0286041 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0284263 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0283238 |
| KRT81 | keratin 81, type II | -0.0280239 |
| PFN1 | profilin 1 | -0.0277209 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0272834 |
| RPL23 | ribosomal protein L23 | -0.0268068 |
| KIAA1549L | KIAA1549-like | -0.0261155 |
| S100A6 | S100 calcium binding protein A6 | -0.0259248 |
| RPLP2 | ribosomal protein, large, P2 | -0.0255719 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0255573 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0250382 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0245472 |
| PCDH7 | protocadherin 7 | -0.0243991 |
| SEC61G | Sec61 gamma subunit | -0.0243024 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0241343 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0240301 |
| PMP22 | peripheral myelin protein 22 | -0.0239653 |
| RPL35 | ribosomal protein L35 | -0.0231571 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0230817 |
| TPM1 | tropomyosin 1 (alpha) | -0.0228073 |
| RPL31 | ribosomal protein L31 | -0.0227957 |
| RPS23 | ribosomal protein S23 | -0.0226264 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0224656 |
| RPS15 | ribosomal protein S15 | -0.021953 |
| FMN2 | formin 2 | -0.0219423 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0209131 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0208747 |
| RPS19 | ribosomal protein S19 | -0.0208697 |
| HMGB1 | high mobility group box 1 | -0.0208194 |
| RPS14 | ribosomal protein S14 | -0.0207299 |
| NAV3 | neuron navigator 3 | -0.0200756 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0198512 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0197058 |
| HLA-C | major histocompatibility complex, class I, C | -0.0196541 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0194702 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0194483 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0194312 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.019239 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0189548 |
| KRT18 | keratin 18, type I | -0.0188153 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0188149 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0188057 |
| TNS3 | tensin 3 | -0.0186881 |
